Growth Metrics

Amicus Therapeutics (FOLD) Gross Margin (2016 - 2025)

Amicus Therapeutics' Gross Margin history spans 10 years, with the latest figure at 85.67% for Q4 2025.

  • For the quarter ending Q4 2025, Gross Margin fell 442.0% year-over-year to 85.67%, compared with a TTM value of 88.5% through Dec 2025, down 148.0%, and an annual FY2025 reading of 88.5%, down 148.0% over the prior year.
  • Gross Margin for Q4 2025 was 85.67% at Amicus Therapeutics, down from 88.49% in the prior quarter.
  • The five-year high for Gross Margin was 91.95% in Q1 2023, with the low at 83.55% in Q3 2022.
  • Average Gross Margin over 5 years is 89.28%, with a median of 90.16% recorded in 2023.
  • Year-over-year, Gross Margin soared 684bps in 2023 and then crashed -442bps in 2025.
  • Tracing FOLD's Gross Margin over 5 years: stood at 90.44% in 2021, then decreased by -1bps to 89.35% in 2022, then grew by 1bps to 90.16% in 2023, then fell by 0bps to 90.09% in 2024, then decreased by -5bps to 85.67% in 2025.
  • Per Business Quant, the three most recent readings for FOLD's Gross Margin are 85.67% (Q4 2025), 88.49% (Q3 2025), and 90.16% (Q2 2025).