Growth Metrics

Amicus Therapeutics (FOLD) Gross Margin (2016 - 2025)

Amicus Therapeutics filings provide 10 years of Gross Margin readings, the most recent being 85.67% for Q4 2025.

  • On a quarterly basis, Gross Margin fell 442.0% to 85.67% in Q4 2025 year-over-year; TTM through Dec 2025 was 88.5%, a 148.0% decrease, with the full-year FY2025 number at 88.5%, down 148.0% from a year prior.
  • Gross Margin hit 85.67% in Q4 2025 for Amicus Therapeutics, down from 88.49% in the prior quarter.
  • In the past five years, Gross Margin ranged from a high of 91.95% in Q1 2023 to a low of 83.55% in Q3 2022.
  • Median Gross Margin over the past 5 years was 90.16% (2023), compared with a mean of 89.28%.
  • Biggest five-year swings in Gross Margin: soared 684bps in 2023 and later crashed -442bps in 2025.
  • Amicus Therapeutics' Gross Margin stood at 90.44% in 2021, then decreased by -1bps to 89.35% in 2022, then grew by 1bps to 90.16% in 2023, then fell by 0bps to 90.09% in 2024, then decreased by -5bps to 85.67% in 2025.
  • The last three reported values for Gross Margin were 85.67% (Q4 2025), 88.49% (Q3 2025), and 90.16% (Q2 2025) per Business Quant data.