Growth Metrics

Amicus Therapeutics (FOLD) Gross Margin (2016 - 2025)

Amicus Therapeutics (FOLD) has disclosed Gross Margin for 10 consecutive years, with 85.67% as the latest value for Q4 2025.

  • For the quarter ending Q4 2025, Gross Margin fell 442.0% year-over-year to 85.67%, compared with a TTM value of 88.5% through Dec 2025, down 148.0%, and an annual FY2025 reading of 88.5%, down 148.0% over the prior year.
  • Gross Margin was 85.67% for Q4 2025 at Amicus Therapeutics, down from 88.49% in the prior quarter.
  • Across five years, Gross Margin topped out at 91.95% in Q1 2023 and bottomed at 83.55% in Q3 2022.
  • Average Gross Margin over 5 years is 89.28%, with a median of 90.16% recorded in 2023.
  • The sharpest move saw Gross Margin surged 684bps in 2023, then tumbled -442bps in 2025.
  • Year by year, Gross Margin stood at 90.44% in 2021, then decreased by -1bps to 89.35% in 2022, then grew by 1bps to 90.16% in 2023, then fell by 0bps to 90.09% in 2024, then decreased by -5bps to 85.67% in 2025.
  • Business Quant data shows Gross Margin for FOLD at 85.67% in Q4 2025, 88.49% in Q3 2025, and 90.16% in Q2 2025.