Growth Metrics

Amicus Therapeutics (FOLD) Net Margin (2016 - 2025)

Amicus Therapeutics filings provide 14 years of Net Margin readings, the most recent being 0.91% for Q4 2025.

  • On a quarterly basis, Net Margin fell 893.0% to 0.91% in Q4 2025 year-over-year; TTM through Dec 2025 was 4.27%, a 635.0% increase, with the full-year FY2025 number at 4.27%, up 635.0% from a year prior.
  • Net Margin hit 0.91% in Q4 2025 for Amicus Therapeutics, down from 10.24% in the prior quarter.
  • In the past five years, Net Margin ranged from a high of 10.24% in Q3 2025 to a low of 108.31% in Q1 2022.
  • Median Net Margin over the past 5 years was 42.3% (2022), compared with a mean of 42.48%.
  • Biggest five-year swings in Net Margin: surged 4807bps in 2021 and later plummeted -1082bps in 2022.
  • Amicus Therapeutics' Net Margin stood at 101.37% in 2021, then surged by 37bps to 63.41% in 2022, then soared by 54bps to 29.41% in 2023, then surged by 133bps to 9.85% in 2024, then crashed by -91bps to 0.91% in 2025.
  • The last three reported values for Net Margin were 0.91% (Q4 2025), 10.24% (Q3 2025), and 15.79% (Q2 2025) per Business Quant data.