Entera Bio (ENTX) Operating Income (2019 - 2026)

Entera Bio (ENTX) posted quarterly Operating Income of -$3.5 million for Q1 2026, down 38.08% year-on-year from -$5.7 million in Q1 2025, and down 16.84% on a QoQ basis from -$3.0 million in Q4 2025.

Entera Bio (ENTX) Operating Income (2019 - 2026) Analysis & Trends

Entera Bio (ENTX) has reported Operating Income for 8 consecutive years, with -$3.5 million the latest figure, recorded in Q1 2026.

  • Quarterly Operating Income fell 38.08% year-over-year to -$3.5 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$12.6 million (down 24.18% YoY) and the FY2025 annual result came in at -$11.5 million, down 20.28% from the prior year.
  • Operating Income slipped to -$3.5 million in Q1 2026 per ENTX's latest filing, from -$3.0 million in the prior quarter.
  • Over the last five years, Operating Income for ENTX reached as high as -$2.0 million in Q4 2023 and fell as low as -$3.8 million in Q1 2022.
  • A 5-year average of -$2.7 million and a median of -$2.7 million in 2025 frame the typical range for Operating Income.
  • Annual changes were most pronounced in 2022 — Operating Income slumped 63.96% — and 2023, when it soared 42.32%.
  • Year by year, Operating Income stood at -$3.1 million in 2022, then surged by 36.02% to -$2.0 million in 2023, then dropped by 19.05% to -$2.3 million in 2024, then fell by 29.61% to -$3.0 million in 2025, then slipped by 16.84% to -$3.5 million in 2026.
  • According to Business Quant data, Operating Income over the past three periods registered -$3.5 million, -$3.0 million, and -$3.3 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Oculis Holding AG 66,621.14 Bn 66,620.85 Bn - -27.75 Mn
2 Nanobiotix 1,915.18 Bn 1,915.11 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.76 Mn
4 BeOne Medicines 471.27 Bn 466.48 Bn 1.35 Bn 249.90 Mn
5 Vertex Pharmaceuticals 121.81 Bn 114.57 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 69.58 Bn 60.82 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 62.72 Bn 62.72 Bn - -32.68 Mn
8 Argenx Se 55.51 Bn 50.33 Bn 1.41 Bn 493.00 Mn
9 Revolution Medicines 37.35 Bn 37.35 Bn - -445.22 Mn
10 Entera Bio 186.78 Mn 182.64 Mn - -3.54 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -3.54 Mn
Dec 31, 2025 -3.03 Mn
Sep 30, 2025 -3.30 Mn
Jun 30, 2025 -2.70 Mn
Mar 31, 2025 -2.56 Mn
Dec 31, 2024 -2.34 Mn
Sep 30, 2024 -3.02 Mn
Jun 30, 2024 -2.20 Mn
Mar 31, 2024 -2.06 Mn
Dec 31, 2023 -1.96 Mn
Sep 30, 2023 -2.39 Mn
Jun 30, 2023 -2.33 Mn
Mar 31, 2023 -2.21 Mn
Dec 31, 2022 -3.07 Mn
Sep 30, 2022 -2.87 Mn
Jun 30, 2022 -3.25 Mn
Mar 31, 2022 -3.84 Mn
Dec 31, 2021 -4.09 Mn
Sep 30, 2021 -3.22 Mn
Jun 30, 2021 -2.57 Mn