Entera Bio (ENTX) Operating Income (2021 - 2026)

Entera Bio (ENTX) recorded quarterly Operating Income of -$3.5 million in Q1 2026, down 16.84% on a QoQ basis from -$3.0 million in Q4 2025, and down 38.08% year-over-year from -$5.7 million in Q1 2025.

Entera Bio (ENTX) Operating Income (2021 - 2026) Analysis & Trends

Entera Bio has disclosed Operating Income across 6 years of filings, most recently posting -$3.5 million for Q1 2026.

  • Quarterly Operating Income fell 38.08% year-over-year to -$3.5 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$12.6 million (down 23.85% YoY) and the FY2025 annual result came in at -$11.5 million, down 20.28% from the prior year.
  • Operating Income slipped to -$3.5 million in Q1 2026, from -$3.0 million in the prior quarter.
  • Over five years, Operating Income peaked at -$2.0 million in Q4 2023 and troughed at -$3.8 million in Q1 2022.
  • A 5-year average of -$2.7 million and a median of -$2.7 million in 2025 frame the typical range for Operating Income.
  • Annual changes were most pronounced in 2022 — Operating Income tumbled 63.96% — and 2023, when it surged 42.32%.
  • Tracing ENTX's Operating Income over 5 years: stood at -$3.1 million in 2022, then jumped by 36.02% to -$2.0 million in 2023, then dropped by 21.5% to -$2.4 million in 2024, then fell by 27.0% to -$3.0 million in 2025, then decreased by 16.84% to -$3.5 million in 2026.
  • Business Quant data shows ENTX's Operating Income at -$3.5 million in Q1 2026, -$3.0 million in Q4 2025, and -$3.3 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Alterity Therapeutics 719,706.53 Bn 719,706.50 Bn - -
2 Belite Bio 55,800.00 Bn 55,800.00 Bn - -32.68 Mn
3 Quantum Biopharma 18,182.30 Bn 18,182.29 Bn - -2.97 Mn
4 Legend Biotech 3,154.00 Bn 3,153.71 Bn 242.10 Mn -19.70 Mn
5 Akari Therapeutics 1,844.30 Bn 1,844.29 Bn - -15.76 Mn
6 Evaxion A 1,567.96 Bn 1,567.94 Bn - -3.82 Mn
7 Psyence Biomedical 251.43 Bn 251.42 Bn - -
8 Vertex Pharmaceuticals 112.56 Bn 105.31 Bn 2.59 Bn 1.14 Bn
9 Abivax 94.37 Bn 94.37 Bn - -65.83 Mn
10 Entera Bio 56.59 Mn 52.45 Mn - -3.54 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -3.54 Mn
Dec 31, 2025 -3.03 Mn
Sep 30, 2025 -3.30 Mn
Jun 30, 2025 -2.70 Mn
Mar 31, 2025 -2.56 Mn
Dec 31, 2024 -2.39 Mn
Sep 30, 2024 -3.00 Mn
Jun 30, 2024 -2.20 Mn
Mar 31, 2024 -2.06 Mn
Dec 31, 2023 -1.96 Mn
Sep 30, 2023 -2.39 Mn
Jun 30, 2023 -2.33 Mn
Mar 31, 2023 -2.21 Mn
Dec 31, 2022 -3.07 Mn
Sep 30, 2022 -2.87 Mn
Jun 30, 2022 -3.25 Mn
Mar 31, 2022 -3.84 Mn
Dec 31, 2021 -4.09 Mn
Sep 30, 2021 -3.22 Mn
Jun 30, 2021 -2.57 Mn