Ensysce Biosciences (ENSC) Return on Sales (2020 - 2025)
Ensysce Biosciences (ENSC) posted quarterly Return on Sales of 0.08% for Q3 2025, down 8.0% year-over-year from 0.08% in Q3 2024, and down 494.33% quarter-over-quarter from 0.01% in Q2 2025.
Ensysce Biosciences (ENSC) Return on Sales (2020 - 2025) Analysis & Trends
Ensysce Biosciences (ENSC) has reported Return on Sales for 6 consecutive years, with 0.08% the latest figure, recorded in Q3 2025.
- In Q3 2025, Return on Sales fell 8.0% year-over-year to 0.08%; the TTM figure through Sep 2025 stood at 0.02% (down 1.0% YoY), while the FY2024 annual figure was 0.02%, up 4.0% from the prior year.
- Return on Sales fell to 0.08% in Q3 2025 per ENSC's latest filing, from 0.01% in the prior quarter.
- Across five years, Return on Sales topped out at 0.0% in Q3 2024 and bottomed at 1.22% in Q2 2021.
- Historically, Return on Sales has averaged 0.14% across 5 years, with a median of 0.06% in 2023.
- Annual changes were most pronounced in 2021 — Return on Sales tumbled 122 bps — and 2022, when it surged 88 bps.
- Ensysce Biosciences' Return on Sales stood at 0.01% in 2021, then tumbled by 242 bps to 0.04% in 2022, then slumped by 40 bps to 0.06% in 2023, then jumped by 55 bps to 0.03% in 2024, then plunged by 177 bps to 0.08% in 2025.
- Business Quant data shows ENSC's Return on Sales at 0.08% in Q3 2025, 0.01% in Q2 2025, and 0.01% in Q1 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROS (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 140.00 Bn | 132.14 Bn | 2.84 Bn | 0.00% |
| 2 | Regeneron Pharmaceuticals | 86.31 Bn | 78.32 Bn | 3.93 Bn | 0.00% |
| 3 | Argenx Se | 65.24 Bn | 60.06 Bn | 1.37 Bn | 0.00% |
| 4 | Moderna | 62.41 Bn | 57.27 Bn | 52.00 Mn | -0.05% |
| 5 | BeOne Medicines | 42.25 Bn | 37.15 Bn | 1.53 Bn | 0.00% |
| 6 | Alnylam Pharmaceuticals | 31.18 Bn | 27.88 Bn | 992.69 Mn | 0.00% |
| 7 | BioNTech SE | 28.93 Bn | 10.54 Bn | 668.28 Mn | 0.00% |
| 8 | Insmed | 27.55 Bn | 26.39 Bn | 358.27 Mn | 0.00% |
| 9 | Royalty Pharma | 27.28 Bn | 26.44 Bn | - | 0.00% |
| 10 | Ensysce Biosciences | 943,416.38 | -3.37 Mn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Sep 30, 2025 | -0.08% |
| Jun 30, 2025 | -0.01% |
| Mar 31, 2025 | -0.01% |
| Dec 31, 2024 | -0.03% |
| Sep 30, 2024 | 0.00% |
| Jun 30, 2024 | -0.11% |
| Mar 31, 2024 | -0.10% |
| Dec 31, 2023 | -0.06% |
| Sep 30, 2023 | -0.06% |
| Jun 30, 2023 | -0.05% |
| Mar 31, 2023 | -0.03% |
| Dec 31, 2022 | -0.04% |
| Sep 30, 2022 | -0.22% |
| Jun 30, 2022 | -0.34% |
| Mar 31, 2022 | -0.08% |
| Dec 31, 2021 | -0.01% |
| Sep 30, 2021 | -0.17% |
| Jun 30, 2021 | -1.22% |
| Mar 31, 2021 | -0.07% |
| Dec 31, 2020 | -0.03% |