Ensysce Biosciences (ENSC) Net Margin (2020 - 2025)
Ensysce Biosciences (ENSC) recorded Net Margin of -756.26% in Q3 2025, down 775.61 percentage points from 19.36% a year earlier and down 629.87 percentage points from the prior quarter.
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Analysis
Ensysce Biosciences (ENSC) Net Margin (2020 - 2025) Analysis & Trends
On a TTM basis, Ensysce Biosciences' Net Margin came in at -244.49% as of Sep 30, 2025, down 65.20 percentage points year-over-year; for FY2024, it came in at -153.30%, up 323.09 percentage points from FY2023.
- Annual Net Margin has a four-year change of -154.75 percentage points (FY2020 to FY2024).
- Across earlier years, Net Margin came in at -476.39% in FY2023 (+517.73 pp), -994.12% in FY2022 (-147.76 pp), -846.37% in FY2021 (-847.81 pp) and 1.44% in FY2020.
- The Q3 2025 figure is the lowest quarterly Net Margin since Q2 2024.
- On a year-over-year basis, Net Margin rose in four of the last eight quarters, with an average year-over-year change of +54.19 percentage points.
- Peak year-over-year performance for Net Margin in the last five years was a gain of 3399.74 percentage points in Q2 2023, against a drop of 3645.15 percentage points in Q2 2022 at the low end.
- Per Business Quant, the preceding three quarters came in at -126.39% (Q2 2025), -147.42% (Q1 2025) and -273.42% (Q4 2024).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 21.86% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 21.27% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -8.04% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 22.61% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 18.81% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 23.62% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -134.51% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | -1.65% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 32.99% |
| 10 | Ensysce Biosciences | 1.02 Mn | -10.55 Mn | - | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2025 | -756.26% |
| Jun 30, 2025 | -126.39% |
| Mar 31, 2025 | -147.42% |
| Dec 31, 2024 | -273.42% |
| Sep 30, 2024 | 19.36% |
| Jun 30, 2024 | -1,082.41% |
| Mar 31, 2024 | -1,019.48% |
| Dec 31, 2023 | -680.40% |
| Sep 30, 2023 | -617.75% |
| Jun 30, 2023 | -455.88% |
| Mar 31, 2023 | -278.13% |
| Dec 31, 2022 | -385.21% |
| Sep 30, 2022 | -3,543.07% |
| Jun 30, 2022 | -3,855.62% |
| Mar 31, 2022 | -276.35% |
| Dec 31, 2021 | -662.88% |
| Sep 30, 2021 | -1,429.32% |
| Jun 30, 2021 | -210.46% |
| Mar 31, 2021 | -362.26% |
| Dec 31, 2020 | 51.38% |
API Access
Ensysce Biosciences Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=ENSC&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "ENSC", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=ENSC&period=max&api_key=YOUR_API_KEY");
const data = await res.json();