Design Therapeutics (DSGN) Return on Capital Employed (2021 - 2026)

Design Therapeutics (DSGN) reported Return on Capital Employed of 36.1% for Q1 2026, down 719.0% on a YoY basis from 5.83% in Q1 2025, and up 6.44% sequentially from 38.59% in Q4 2025.

Design Therapeutics (DSGN) Return on Capital Employed (2021 - 2026) Analysis & Trends

Design Therapeutics (DSGN) has 6 years of Return on Capital Employed data on file, last reported at 36.1% in Q1 2026.

  • For the quarter ending Q1 2026, Return on Capital Employed fell 719.0% year-over-year to 36.1%; the trailing twelve-month figure through Mar 2026 stood at 36.1% (down 719.0% YoY), and the FY2025 full-year result was 35.15%, down 1137.0% from the prior year.
  • Return on Capital Employed grew to 36.1% in Q1 2026, from 38.59% in the prior quarter.
  • In the past five years, Return on Capital Employed ranged from a high of 11.48% in Q1 2022 to a low of 38.59% in Q4 2025.
  • A 5-year average of 25.98% and a median of 25.6% in 2024 frame the typical range for Return on Capital Employed.
  • Across the five-year window, Return on Capital Employed surged 456 bps in 2024 and plunged 1428 bps in 2025, its largest moves.
  • Tracing DSGN's Return on Capital Employed over 5 years: stood at 20.05% in 2022, then sank by 37 bps to 27.42% in 2023, then gained by 8 bps to 25.11% in 2024, then plunged by 54 bps to 38.59% in 2025, then advanced by 6 bps to 36.1% in 2026.
  • Business Quant data shows DSGN's Return on Capital Employed at 36.1% in Q1 2026, 38.59% in Q4 2025, and 37.83% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -31.80%
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 10.46%
4 NuCana 279.75 Bn 279.75 Bn - -68.47%
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 21.10%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 10.19%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -68.84%
10 Design Therapeutics 714.48 Mn 491.66 Mn - -36.10%

Historic Data

Download Data
DateValue
Mar 31, 2026 -36.10%
Dec 31, 2025 -38.59%
Sep 30, 2025 -37.83%
Jun 30, 2025 -33.84%
Mar 31, 2025 -28.92%
Dec 31, 2024 -25.11%
Sep 30, 2024 -23.55%
Jun 30, 2024 -23.67%
Mar 31, 2024 -25.60%
Dec 31, 2023 -27.42%
Sep 30, 2023 -28.11%
Jun 30, 2023 -27.06%
Mar 31, 2023 -23.43%
Dec 31, 2022 -20.05%
Sep 30, 2022 -16.91%
Jun 30, 2022 -14.06%
Mar 31, 2022 -11.48%
Dec 31, 2021 -9.18%
Sep 30, 2021 -7.19%
Jun 30, 2021 -4.84%