Design Therapeutics (DSGN) Return on Capital Employed (2021 - 2026)
Design Therapeutics' (DSGN) quarterly Return on Capital Employed came in at 36.1% in Q1 2026, down 719.0% year-on-year from 5.83% in Q1 2025, and up 6.44% quarter-over-quarter from 38.59% in Q4 2025.
Design Therapeutics (DSGN) Return on Capital Employed (2021 - 2026) Analysis & Trends
Design Therapeutics has disclosed Return on Capital Employed across 6 years of filings, most recently posting 36.1% for Q1 2026.
- Return on Capital Employed for Q1 2026 came in at 36.1%, down 719.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 36.1% (down 719.0% YoY), and the FY2025 annual result was 35.15%, down 1137.0% from the prior year.
- Return on Capital Employed came in at 36.1% for Q1 2026 at Design Therapeutics, up from 38.59% in the prior quarter.
- In the past five years, Return on Capital Employed ranged from a high of 11.48% in Q1 2022 to a low of 38.59% in Q4 2025.
- The 5-year median for Return on Capital Employed is 25.6% (2024), against an average of 25.98%.
- Across the five-year window, Return on Capital Employed surged 456 bps in 2024 and slumped 1428 bps in 2025, its largest moves.
- Design Therapeutics' Return on Capital Employed stood at 20.05% in 2022, then plunged by 37 bps to 27.42% in 2023, then advanced by 8 bps to 25.11% in 2024, then tumbled by 54 bps to 38.59% in 2025, then climbed by 6 bps to 36.1% in 2026.
- The last three Return on Capital Employed figures came in at 36.1% (Q1 2026), 38.59% (Q4 2025), and 37.83% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROCE (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | 450.31% |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 51.73% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -107.40% |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 21.10% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -50.43% |
| 10 | Design Therapeutics | 763.94 Mn | 541.11 Mn | - | -36.10% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -36.10% |
| Dec 31, 2025 | -38.59% |
| Sep 30, 2025 | -37.83% |
| Jun 30, 2025 | -33.84% |
| Mar 31, 2025 | -28.92% |
| Dec 31, 2024 | -25.11% |
| Sep 30, 2024 | -23.55% |
| Jun 30, 2024 | -23.67% |
| Mar 31, 2024 | -25.60% |
| Dec 31, 2023 | -27.42% |
| Sep 30, 2023 | -28.11% |
| Jun 30, 2023 | -27.06% |
| Mar 31, 2023 | -23.43% |
| Dec 31, 2022 | -20.05% |
| Sep 30, 2022 | -16.91% |
| Jun 30, 2022 | -14.06% |
| Mar 31, 2022 | -11.48% |
| Dec 31, 2021 | -9.18% |
| Sep 30, 2021 | -7.19% |
| Jun 30, 2021 | -4.84% |