Design Therapeutics (DSGN) Return on Capital Employed (2021 - 2026)

Design Therapeutics recorded quarterly Return on Capital Employed of 36.1% in Q1 2026, up 6.44% quarter-over-quarter from 38.59% in Q4 2025, and down 719.0% year-over-year from 5.83% in Q1 2025.

Design Therapeutics' Return on Capital Employed history runs 6 years deep, the most recent figure standing at 36.1% for Q1 2026.

  • In Q1 2026, Return on Capital Employed fell 719.0% year-over-year to 36.1%; the TTM figure through Mar 2026 stood at 36.1% (down 719.0% YoY), while the FY2025 annual figure was 35.15%, down 1137.0% from the prior year.
  • Return on Capital Employed came in at 36.1% for Q1 2026 at Design Therapeutics, up from 38.59% in the prior quarter.
  • In the past five years, Return on Capital Employed ranged from a high of 11.48% in Q1 2022 to a low of 38.59% in Q4 2025.
  • A 5-year average of 25.98% and a median of 25.6% in 2024 frame the typical range for Return on Capital Employed.
  • Across the five-year window, Return on Capital Employed soared 456 bps in 2024 and sank 1428 bps in 2025, its largest moves.
  • Design Therapeutics' Return on Capital Employed stood at 20.05% in 2022, then tumbled by 37 bps to 27.42% in 2023, then climbed by 8 bps to 25.11% in 2024, then slumped by 54 bps to 38.59% in 2025, then grew by 6 bps to 36.1% in 2026.
  • According to Business Quant data, Return on Capital Employed over the past three periods registered 36.1%, 38.59%, and 37.83% for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 450.31%
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 51.73%
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -107.40%
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 21.10%
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 10.19%
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 20.34%
10 Design Therapeutics 640.15 Mn 417.32 Mn - -36.10%

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 -36.10%
Dec 31, 2025 -38.59%
Sep 30, 2025 -37.83%
Jun 30, 2025 -33.84%
Mar 31, 2025 -28.92%
Dec 31, 2024 -25.11%
Sep 30, 2024 -23.55%
Jun 30, 2024 -23.67%
Mar 31, 2024 -25.60%
Dec 31, 2023 -27.42%
Sep 30, 2023 -28.11%
Jun 30, 2023 -27.06%
Mar 31, 2023 -23.43%
Dec 31, 2022 -20.05%
Sep 30, 2022 -16.91%
Jun 30, 2022 -14.06%
Mar 31, 2022 -11.48%
Dec 31, 2021 -9.18%
Sep 30, 2021 -7.19%
Jun 30, 2021 -4.84%
Mar 31, 2021 -6.07%