Design Therapeutics DSGN Institutional Ownership

NASDAQ DSGN

$15.14 +0.11 (+0.73%)

As of: Sep 4, 2026 · 3:59 PM EDT

Institutions by Trading Activity

138 Institutions

Increased 91 65.9%

Unchanged 14 10.1%

Reduced 33 23.9%

Ownership Statistics

13F · as of 30 Jun, 2026

Institutional Ownership

69.72%

▲+7.88 pp QoQ

Shares Held by Institutions

43.58Mn

of 62.51Mn outstanding

▲+29.46% QoQ

Shares Outstanding

62.51Mn

18.93Mn held outside 13F filers

Institutional Investors

138

filed 13F for Jun 2026

▲+13 vs prior quarter

Net Shares Added (QoQ)

+9.92Mn

accumulated since last quarter

Value of Holdings

$654.95Mn

reported market value

Shares Owned by Institutions

Shares held % of outstanding

Latest —

Average ownership —

Peak ownership —

Shares Purchased/Sold by Institutions

Accumulated Distributed

Latest quarter —

Net over range —

Accumulating quarters —

Ownership Summary

Quarter ending 30 Jun, 2026

Design Therapeutics, Inc. (NASDAQ:DSGN) has 138 institutional investors with active 13F positions as of June 2026.

These investors held 69.7% of outstanding shares in June 2026, up from 61.8% in March 2026.
They increased total shares held in Design Therapeutics by 29.46% from last quarter, and the number of investors in DSGN increased 51.65% annually.
Activity in DSGN broke down as 91 buyers, 33 sellers, and 14 unchanged among 138 total holders.
Institutional investors collectively held 43.58Mn shares in Design Therapeutics as of June 2026, up by 9.92Mn shares quarter on quarter, and up 9.86Mn shares year over year.
As of June 30, 2026, the biggest holder of Design Therapeutics is SR ONE CAPITAL MANAGEMENT, LP at 6.53Mn shares, representing 10.44% of shares outstanding.
The biggest buyers of Design Therapeutics for the quarter ending June 2026 included Frazier Life Sciences Management, L.P. (1.81Mn), Trails Edge Capital Partners, LP (1.15Mn), Logos Global Management LP (1.05Mn), Caption Management, LLC (1.03Mn), DRIEHAUS CAPITAL MANAGEMENT LLC (916.13K).
The largest sales of DSGN for the quarter ending June 2026 came from Almitas Capital LLC (503.44K), Point72 Asset Management, L.P. (356.3K), D. E. Shaw & Co., Inc. (274.62K), Woodline Partners LP (261.15K), CITADEL ADVISORS LLC (149.54K).
According to Business Quant data, leading holders of DSGN for June 2026 are SR ONE CAPITAL MANAGEMENT, LP (6.53Mn), Logos Global Management LP (3.0Mn), BAKER BROS. ADVISORS LP (2.68Mn), DRIEHAUS CAPITAL MANAGEMENT LLC (2.66Mn), BlackRock, Inc. (2.66Mn), Point72 Asset Management, L.P. (2.37Mn), Trails Edge Capital Partners, LP (2.0Mn), Frazier Life Sciences Management, L.P. (1.81Mn), Vivo Capital, LLC (1.61Mn), VANGUARD CAPITAL MANAGEMENT LLC (1.57Mn).

Form 13F Holdings

138 Institutional Holders

Report period 30 Jun, 2026

Total shares held 43.58Mn

Of outstanding 69.72%

#	Institution	CIK	Shares Held	% of Outstanding	Change (QoQ)	Change (%)	Value (USD)
1	SR ONE CAPITAL MANAGEMENT, LP	0001910264	6,526,476	10.44%	0	0.00%	$94.44Mn
2	Logos Global Management LP	0001792126	3,000,000	4.80%	▲1,050,000	+53.85%	$43.41Mn
3	BAKER BROS. ADVISORS LP	0001263508	2,678,430	4.29%	▲92,452	+3.58%	$38.76Mn
4	DRIEHAUS CAPITAL MANAGEMENT LLC	0000938206	2,661,115	4.26%	▲916,128	+52.50%	$38.51Mn
5	BlackRock, Inc.	0002012383	2,660,024	4.26%	▲526,260	+24.66%	$38.49Mn
6	Point72 Asset Management, L.P.	0001603466	2,366,453	3.79%	▼356,301	-13.09%	$34.24Mn
7	Trails Edge Capital Partners, LP	0002077247	2,001,282	3.20%	▲1,149,269	+134.89%	$28.96Mn
8	Frazier Life Sciences Management, L.P.	0001892134	1,809,854	2.90%	▲1,809,854	0.00%	$26.19Mn
9	Vivo Capital, LLC	0001674712	1,612,903	2.58%	0	0.00%	$23.34Mn
10	VANGUARD CAPITAL MANAGEMENT LLC	0002100119	1,571,022	2.51%	▲221,172	+16.38%	$22.73Mn
11	Caption Management, LLC	0001706766	1,118,098	1.79%	▲1,031,390	+1,189.50%	$16.18Mn
12	Almitas Capital LLC	0001596468	1,026,893	1.64%	▼503,442	-32.90%	$14.86Mn
13	GEODE CAPITAL MANAGEMENT, LLC	0001214717	958,417	1.53%	▲265,899	+38.40%	$13.87Mn
14	Sofinnova Investments, Inc.	0001631134	865,135	1.38%	▲865,135	0.00%	$12.52Mn
15	FMR LLC	0000315066	776,462	1.24%	▼21,949	-2.75%	$11.24Mn
16	Morgan Stanley	0000895421	765,425	1.22%	▲108,860	+16.58%	$11.08Mn
17	State Street Corp	0000093751	736,221	1.18%	▲76,646	+11.62%	$10.65Mn
18	Woodline Partners LP	0001784547	700,354	1.12%	▼261,147	-27.16%	$10.13Mn
19	DIMENSIONAL FUND ADVISORS LP	0000354204	694,743	1.11%	▲262,903	+60.88%	$10.05Mn
20	Goldman Sachs Group Inc	0000886982	656,584	1.05%	▲151,866	+30.09%	$9.50Mn

Showing 1 to 20 of 138 holders