Definium Therapeutics (DFTX) Return on Capital Employed (2022 - 2026)

Definium Therapeutics (DFTX) posted quarterly Return on Capital Employed of 56.94% for Q1 2026, down 1285.0% year-over-year from 4.81% in Q1 2025, and up 6.93% quarter-over-quarter from 61.19% in Q4 2025.

Definium Therapeutics (DFTX) Return on Capital Employed (2022 - 2026) Analysis & Trends

Definium Therapeutics (DFTX) has reported Return on Capital Employed for 5 consecutive years, with 56.94% the latest figure, recorded in Q1 2026.

  • In Q1 2026, Return on Capital Employed fell 1285.0% year-over-year to 56.94%; the TTM figure through Mar 2026 stood at 56.94% (down 1285.0% YoY), while the FY2025 annual figure was 54.63%, up 492.0% from the prior year.
  • Return on Capital Employed improved to 56.94% in Q1 2026 per DFTX's latest filing, from 61.19% in the prior quarter.
  • Across five years, Return on Capital Employed topped out at 35.93% in Q3 2024 and bottomed at 93.12% in Q4 2023.
  • Historically, Return on Capital Employed has averaged 58.25% across 5 years, with a median of 56.11% in 2025.
  • Annual changes were most pronounced in 2023 — Return on Capital Employed sank 5102 bps — and 2024, when it jumped 5493 bps.
  • Definium Therapeutics' Return on Capital Employed stood at 42.1% in 2022, then tumbled by 121 bps to 93.12% in 2023, then surged by 59 bps to 38.19% in 2024, then tumbled by 60 bps to 61.19% in 2025, then advanced by 7 bps to 56.94% in 2026.
  • Business Quant data shows DFTX's Return on Capital Employed at 56.94% in Q1 2026, 61.19% in Q4 2025, and 81.47% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 20.76%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 10.74%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -
4 Revolution Medicines 43.64 Bn 43.64 Bn - -55.45%
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 13.68%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -0.20%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 7.88%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 26.09%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -50.93%
10 Definium Therapeutics 4.72 Bn 4.72 Bn - -37.93%

Historic Data

Download Data
DateValue
Jun 30, 2026 -37.93%
Mar 31, 2026 -56.94%
Dec 31, 2025 -61.19%
Sep 30, 2025 -81.47%
Jun 30, 2025 -56.11%
Mar 31, 2025 -44.09%
Dec 31, 2024 -38.19%
Sep 30, 2024 -35.93%
Jun 30, 2024 -39.34%
Mar 31, 2024 -70.65%
Dec 31, 2023 -93.12%
Sep 30, 2023 -77.32%
Jun 30, 2023 -71.19%
Mar 31, 2023 -49.54%
Dec 31, 2022 -42.10%
Sep 30, 2022 -53.20%
Jun 30, 2022 -52.46%
Mar 31, 2022 -67.45%