Growth Metrics

Definium Therapeutics (DFTX) Return on Capital Employed (2020 - 2026)

Definium Therapeutics (DFTX) reported Return on Capital Employed of 56.94% for Q1 2026, down 1285.0% year-over-year from 4.81% in Q1 2025, and up 6.93% on a QoQ basis from 61.19% in Q4 2025.

Definium Therapeutics (DFTX) has 7 years of Return on Capital Employed data on file, last reported at 56.94% in Q1 2026.

  • Quarterly Return on Capital Employed fell 1285.0% year-over-year to 56.94% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 56.94% (down 1285.0% YoY) and the FY2025 annual result came in at 54.63%, up 492.0% from the prior year.
  • Return on Capital Employed advanced to 56.94% in Q1 2026 per DFTX's latest filing, from 61.19% in the prior quarter.
  • Across five years, Return on Capital Employed topped out at 3.1% in Q3 2022 and bottomed at 93.12% in Q4 2023.
  • The 5-year median for Return on Capital Employed is 49.54% (2023), against an average of 48.7%.
  • The widest annual swing landed in 2023, when Return on Capital Employed plunged 8042 bps; it then surged 5493 bps in 2024.
  • Tracing DFTX's Return on Capital Employed over 5 years: stood at 42.1% in 2022, then plunged by 121 bps to 93.12% in 2023, then surged by 59 bps to 38.19% in 2024, then plunged by 60 bps to 61.19% in 2025, then increased by 7 bps to 56.94% in 2026.
  • Per Business Quant, the three latest DFTX Return on Capital Employed figures stand at 56.94% (Q1 2026), 61.19% (Q4 2025), and 81.47% (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - 450.31%
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn 51.73%
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -107.40%
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 21.10%
7 Evaxion A 64.16 Bn 64.14 Bn - -
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 10.19%
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 20.34%
10 Definium Therapeutics 2.42 Bn 2.06 Bn - -56.94%

Historic Data

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DateValue
Mar 31, 2026 -56.94%
Dec 31, 2025 -61.19%
Sep 30, 2025 -81.47%
Jun 30, 2025 -56.11%
Mar 31, 2025 -44.09%
Dec 31, 2024 -38.19%
Sep 30, 2024 -35.93%
Jun 30, 2024 -39.34%
Mar 31, 2024 -70.65%
Dec 31, 2023 -93.12%
Sep 30, 2023 -77.32%
Jun 30, 2023 -71.19%
Mar 31, 2023 -49.54%
Dec 31, 2022 -42.10%
Sep 30, 2022 3.10%
Jun 30, 2022 2.87%
Mar 31, 2022 -16.73%
Dec 31, 2021 -12.29%
Dec 31, 2020 -41.69%