Definium Therapeutics (DFTX) Free Cash Flow (2021 - 2026)

Definium Therapeutics (DFTX) posted quarterly Free Cash Flow of -$42.5 million for Q1 2026, down 44.46% year-over-year from -$76.5 million in Q1 2025, and up 1.04% quarter-over-quarter from -$43.0 million in Q4 2025.

Definium Therapeutics (DFTX) Free Cash Flow (2021 - 2026) Analysis & Trends

Definium Therapeutics (DFTX) has reported Free Cash Flow for 6 consecutive years, with -$42.5 million the latest figure, recorded in Q1 2026.

  • In Q1 2026, Free Cash Flow fell 44.46% year-over-year to -$42.5 million; the TTM figure through Mar 2026 stood at -$144.6 million (down 57.23% YoY), while the FY2025 annual figure was -$131.5 million, down 66.32% from the prior year.
  • Free Cash Flow grew to -$42.5 million in Q1 2026 per DFTX's latest filing, from -$43.0 million in the prior quarter.
  • Across five years, Free Cash Flow topped out at -$9.3 million in Q3 2022 and bottomed at -$43.0 million in Q4 2025.
  • Historically, Free Cash Flow has averaged -$21.6 million across 5 years, with a median of -$17.2 million in 2024.
  • Annual changes were most pronounced in 2022 — Free Cash Flow surged 44.6% — and 2023, when it slumped 78.56%.
  • Definium Therapeutics' Free Cash Flow stood at -$12.8 million in 2022, then plunged by 60.11% to -$20.6 million in 2023, then retreated by 23.56% to -$25.4 million in 2024, then slumped by 69.01% to -$43.0 million in 2025, then gained by 1.04% to -$42.5 million in 2026.
  • Business Quant data shows DFTX's Free Cash Flow at -$42.5 million in Q1 2026, -$43.0 million in Q4 2025, and -$29.6 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 1.01 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 572.80 Mn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -
4 Revolution Medicines 43.64 Bn 43.64 Bn - -389.61 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 437.80 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -2.33 Mn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 477.44 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 292.04 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -95.09 Mn
10 Definium Therapeutics 4.72 Bn 4.72 Bn - -52.91 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -52.91 Mn
Jun 30, 2026 -52.91 Mn
Mar 31, 2026 -42.51 Mn
Mar 31, 2026 -42.51 Mn
Dec 31, 2025 -42.96 Mn
Dec 31, 2025 -42.96 Mn
Sep 30, 2025 -29.56 Mn
Sep 30, 2025 -29.56 Mn
Jun 30, 2025 -29.59 Mn
Jun 30, 2025 -29.59 Mn
Mar 31, 2025 -29.43 Mn
Mar 31, 2025 -29.43 Mn
Dec 31, 2024 -25.42 Mn
Dec 31, 2024 -25.42 Mn
Sep 30, 2024 -17.17 Mn
Sep 30, 2024 -17.17 Mn
Jun 30, 2024 -19.97 Mn
Jun 30, 2024 -19.97 Mn
Mar 31, 2024 -16.53 Mn
Mar 31, 2024 -16.53 Mn