Growth Metrics

Definium Therapeutics (DFTX) Free Cash Flow (2019 - 2026)

Definium Therapeutics (DFTX) reported Free Cash Flow of -$42.6 million for Q1 2026, down 44.91% year-over-year from -$77.4 million in Q1 2025, and up 0.8% on a QoQ basis from -$43.0 million in Q4 2025.

Definium Therapeutics (DFTX) has 8 years of Free Cash Flow data on file, last reported at -$42.6 million in Q1 2026.

  • Quarterly Free Cash Flow fell 44.91% year-over-year to -$42.6 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$144.8 million (down 57.45% YoY) and the FY2025 annual result came in at -$131.6 million, down 66.26% from the prior year.
  • Free Cash Flow rose to -$42.6 million in Q1 2026 per DFTX's latest filing, from -$43.0 million in the prior quarter.
  • Across five years, Free Cash Flow topped out at -$9.3 million in Q3 2022 and bottomed at -$43.0 million in Q4 2025.
  • The 5-year median for Free Cash Flow is -$17.2 million (2024), against an average of -$21.6 million.
  • The widest annual swing landed in 2022, when Free Cash Flow soared 44.6%; it then tumbled 78.83% in 2023.
  • Tracing DFTX's Free Cash Flow over 5 years: stood at -$12.8 million in 2022, then tumbled by 60.04% to -$20.6 million in 2023, then declined by 23.28% to -$25.4 million in 2024, then tumbled by 69.52% to -$43.0 million in 2025, then advanced by 0.8% to -$42.6 million in 2026.
  • Per Business Quant, the three latest DFTX Free Cash Flow figures stand at -$42.6 million (Q1 2026), -$43.0 million (Q4 2025), and -$29.6 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -1.67 Mn
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -12.20 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -2.49 Mn
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 1.29 Bn
7 Evaxion A 64.16 Bn 64.14 Bn - -
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 848.30 Mn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 48.67 Mn
10 Definium Therapeutics 2.42 Bn 2.06 Bn - -42.63 Mn

Historic Data

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DateValue
Mar 31, 2026 -42.63 Mn
Mar 31, 2026 -42.63 Mn
Dec 31, 2025 -42.98 Mn
Dec 31, 2025 -42.98 Mn
Sep 30, 2025 -29.57 Mn
Sep 30, 2025 -29.57 Mn
Jun 30, 2025 -29.60 Mn
Jun 30, 2025 -29.60 Mn
Mar 31, 2025 -29.42 Mn
Mar 31, 2025 -29.42 Mn
Dec 31, 2024 -25.35 Mn
Dec 31, 2024 -25.35 Mn
Sep 30, 2024 -17.19 Mn
Sep 30, 2024 -17.19 Mn
Jun 30, 2024 -19.99 Mn
Jun 30, 2024 -19.99 Mn
Mar 31, 2024 -16.60 Mn
Mar 31, 2024 -16.60 Mn
Dec 31, 2023 -20.56 Mn
Dec 31, 2023 -20.56 Mn
Sep 30, 2023 -16.63 Mn
Sep 30, 2023 -16.63 Mn
Jun 30, 2023 -13.85 Mn
Jun 30, 2023 -13.85 Mn
Mar 31, 2023 -13.33 Mn
Mar 31, 2023 -13.33 Mn
Dec 31, 2022 -12.85 Mn
Dec 31, 2022 -12.85 Mn
Sep 30, 2022 -9.30 Mn
Sep 30, 2022 -9.30 Mn
Jun 30, 2022 -15.13 Mn
Jun 30, 2022 -15.13 Mn
Mar 31, 2022 -12.87 Mn
Mar 31, 2022 -12.87 Mn
Dec 31, 2021 -7.83 Mn
Dec 31, 2021 -7.83 Mn
Sep 30, 2021 -16.78 Mn
Sep 30, 2021 -16.78 Mn
Jun 30, 2021 -11.17 Mn
Jun 30, 2021 -11.17 Mn
Mar 31, 2021 -10.04 Mn
Mar 31, 2021 -10.04 Mn
Dec 31, 2020 -7.14 Mn
Dec 31, 2020 -7.14 Mn
Sep 30, 2020 -5.80 Mn
Sep 30, 2020 -5.80 Mn
Jun 30, 2020 -5.55 Mn
Jun 30, 2020 -5.55 Mn
Mar 31, 2020 -5.10 Mn
Mar 31, 2020 -5.10 Mn
Dec 31, 2019 -3.20 Mn
Dec 31, 2019 -3.20 Mn