Growth Metrics

Definium Therapeutics (DFTX) Change in Cash (2019 - 2026)

Definium Therapeutics (DFTX) reported Change in Cash of $4.7 million for Q1 2026, up 102.45% year-over-year from $2.3 million in Q1 2025, and down 98.03% on a QoQ basis from $237.9 million in Q4 2025.

Definium Therapeutics (DFTX) has 8 years of Change in Cash data on file, last reported at $4.7 million in Q1 2026.

  • Quarterly Change in Cash rose 102.45% year-over-year to $4.7 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $179.7 million (up 206.01% YoY) and the FY2025 annual result came in at -$15.9 million, down 109.14% from the prior year.
  • Change in Cash declined to $4.7 million in Q1 2026 per DFTX's latest filing, from $237.9 million in the prior quarter.
  • Across five years, Change in Cash topped out at $237.9 million in Q4 2025 and bottomed at -$190.9 million in Q1 2025.
  • The 5-year median for Change in Cash is -$12.5 million (2023), against an average of $7.6 million.
  • The widest annual swing landed in 2024, when Change in Cash jumped 6386.57%; it then plunged 437.63% in 2025.
  • Tracing DFTX's Change in Cash over 5 years: stood at -$12.4 million in 2022, then plunged by 45.39% to -$18.0 million in 2023, then slipped by 19.72% to -$21.5 million in 2024, then soared by 1204.2% to $237.9 million in 2025, then sank by 98.03% to $4.7 million in 2026.
  • Per Business Quant, the three latest DFTX Change in Cash figures stand at $4.7 million (Q1 2026), $237.9 million (Q4 2025), and -$13.4 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - 2.44 Mn
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn 623.00 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -2.44 Mn
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 417.10 Mn
7 Evaxion A 64.16 Bn 64.14 Bn - -
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn -153.10 Mn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 53.61 Mn
10 Definium Therapeutics 2.42 Bn 2.06 Bn - 4.68 Mn

Historic Data

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DateValue
Mar 31, 2026 4.68 Mn
Dec 31, 2025 237.88 Mn
Sep 30, 2025 -13.43 Mn
Jun 30, 2025 -49.46 Mn
Mar 31, 2025 -190.89 Mn
Dec 31, 2024 -21.54 Mn
Sep 30, 2024 52.15 Mn
Jun 30, 2024 -9.20 Mn
Mar 31, 2024 152.63 Mn
Dec 31, 2023 -18.00 Mn
Sep 30, 2023 804,000.00
Jun 30, 2023 -12.51 Mn
Mar 31, 2023 -12.73 Mn
Dec 31, 2022 -12.38 Mn
Sep 30, 2022 48.78 Mn
Jun 30, 2022 -14.73 Mn
Mar 31, 2022 -13.07 Mn
Dec 31, 2021 -12.38 Mn
Sep 30, 2021 -11.18 Mn
Jun 30, 2021 -2.94 Mn
Mar 31, 2021 79.95 Mn
Dec 31, 2020 -42.14 Mn
Sep 30, 2020 98.17 Mn
Jun 30, 2020 3.56 Mn
Mar 31, 2020 13.81 Mn
Dec 31, 2019 6.70 Mn