Cytokinetics (CYTK) Operating Income (2010 - 2026)

Cytokinetics (CYTK) posted quarterly Operating Income of -$183.6 million for Q1 2026, down 17.98% year-over-year from -$223.9 million in Q1 2025, and down 2.94% quarter-over-quarter from -$178.4 million in Q4 2025.

Cytokinetics (CYTK) Operating Income (2010 - 2026) Analysis & Trends

Cytokinetics (CYTK) has reported Operating Income for 17 consecutive years, with -$183.6 million the latest figure, recorded in Q1 2026.

  • In Q1 2026, Operating Income fell 17.98% year-over-year to -$183.6 million; the TTM figure through Mar 2026 stood at -$640.2 million (down 13.19% YoY), while the FY2025 annual figure was -$612.3 million, down 14.17% from the prior year.
  • Operating Income eased to -$183.6 million in Q1 2026 per CYTK's latest filing, from -$178.4 million in the prior quarter.
  • Across five years, Operating Income topped out at -$10.9 million in Q2 2022 and bottomed at -$183.6 million in Q1 2026.
  • Historically, Operating Income has averaged -$126.6 million across 5 years, with a median of -$127.0 million in 2022.
  • Annual changes were most pronounced in 2022 — Operating Income soared 80.16% — and 2023, when it slumped 1022.39%.
  • Cytokinetics' Operating Income stood at -$127.0 million in 2022, then slipped by 0.31% to -$127.4 million in 2023, then declined by 9.12% to -$139.0 million in 2024, then retreated by 28.28% to -$178.4 million in 2025, then retreated by 2.94% to -$183.6 million in 2026.
  • Business Quant data shows CYTK's Operating Income at -$183.6 million in Q1 2026, -$178.4 million in Q4 2025, and -$166.8 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 1.25 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 1.29 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 493.00 Mn
4 Revolution Medicines 43.64 Bn 43.64 Bn - -505.13 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 325.05 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -3,158.03
7 Royalty Pharma 33.72 Bn 35.84 Bn - 133.12 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 231.44 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -1.55 Mn
10 Cytokinetics 10.31 Bn 9.14 Bn 25.89 Mn -179.17 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -179.17 Mn
Mar 31, 2026 -183.62 Mn
Dec 31, 2025 -178.37 Mn
Sep 30, 2025 -166.76 Mn
Jun 30, 2025 -111.51 Mn
Mar 31, 2025 -155.63 Mn
Dec 31, 2024 -139.04 Mn
Sep 30, 2024 -140.80 Mn
Jun 30, 2024 -130.17 Mn
Mar 31, 2024 -126.24 Mn
Dec 31, 2023 -127.42 Mn
Sep 30, 2023 -122.27 Mn
Jun 30, 2023 -122.05 Mn
Mar 31, 2023 -124.47 Mn
Dec 31, 2022 -127.03 Mn
Sep 30, 2022 -108.44 Mn
Jun 30, 2022 -10.87 Mn
Mar 31, 2022 -77.86 Mn
Dec 31, 2021 -21.70 Mn
Sep 30, 2021 -69.20 Mn