Cue Biopharma CUE
NASDAQ CUE
$23.98 -0.63 (-2.56%)
At close: Aug 21, 2026 · 4:00 PM EDT

Cue Biopharma (CUE) Research & Development (2017 - 2025)

Cue Biopharma (CUE) posted Research & Development of $16.5 million for Q4 2025, up 247.75% sequentially from $4.8 million in Q3 2025, and up 130.12% YoY from $7.2 million in Q4 2024.

Cue Biopharma (CUE) Research & Development (2017 - 2025) Analysis & Trends

Cue Biopharma has reported Research & Development for 9 years, with the latest figure at $16.5 million in Q4 2025.

  • Quarterly Research & Development rose 130.12% year-over-year to $16.5 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was $37.7 million (up 3.99% YoY) and the FY2025 annual result came in at $37.7 million, up 3.99% from the prior year.
  • Research & Development advanced to $16.5 million in Q4 2025 per CUE's latest filing, from $4.8 million in the prior quarter.
  • Over five years, Research & Development peaked at $16.5 million in Q4 2025 and troughed at $4.8 million in Q3 2025.
  • A 5-year average of $9.7 million and a median of $9.7 million in 2021 frame the typical range for Research & Development.
  • The widest YoY moves for Research & Development: up 130.12% in 2025, down 49.32% in 2025.
  • Over 5 years, Research & Development stood at $11.5 million in 2021, then fell by 1.47% to $11.3 million in 2022, then dropped by 3.93% to $10.9 million in 2023, then slumped by 34.01% to $7.2 million in 2024, then jumped by 130.12% to $16.5 million in 2025.
  • According to Business Quant data, Research & Development over the past three periods registered $16.5 million, $4.8 million, and $7.9 million for Q4 2025, Q3 2025, and Q2 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) R&D (Qtr)
1 Vertex Pharmaceuticals 139.13 Bn 131.28 Bn 2.84 Bn 993.80 Mn
2 Regeneron Pharmaceuticals 85.77 Bn 77.77 Bn 3.93 Bn 1.63 Bn
3 Argenx Se 64.64 Bn 59.46 Bn 1.37 Bn 1.37 Bn
4 Moderna 58.29 Bn 53.16 Bn 52.00 Mn 651.00 Mn
5 BeOne Medicines 41.92 Bn 36.82 Bn 1.53 Bn 612.28 Mn
6 Alnylam Pharmaceuticals 31.58 Bn 28.28 Bn 992.69 Mn 413.13 Mn
7 BioNTech SE 28.12 Bn 9.73 Bn 668.28 Mn -588.31 Mn
8 Insmed 27.39 Bn 26.22 Bn 358.27 Mn 210.03 Mn
9 Royalty Pharma 27.27 Bn 26.43 Bn - 97.90 Mn
10 Cue Biopharma 152.56 Mn 135.14 Mn - 49.01 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 16.53 Mn
Sep 30, 2025 4.75 Mn
Jun 30, 2025 7.91 Mn
Mar 31, 2025 8.55 Mn
Dec 31, 2024 7.18 Mn
Sep 30, 2024 9.38 Mn
Jun 30, 2024 9.53 Mn
Mar 31, 2024 10.20 Mn
Dec 31, 2023 10.89 Mn
Sep 30, 2023 9.87 Mn
Jun 30, 2023 10.65 Mn
Mar 31, 2023 9.39 Mn
Dec 31, 2022 11.33 Mn
Sep 30, 2022 7.57 Mn
Jun 30, 2022 9.59 Mn
Mar 31, 2022 10.08 Mn
Dec 31, 2021 11.50 Mn
Sep 30, 2021 11.29 Mn
Jun 30, 2021 8.76 Mn
Mar 31, 2021 9.82 Mn