Cue Biopharma (CUE) Research & Development (2017 - 2025)

Cue Biopharma's (CUE) quarterly Research & Development came in at $16.5 million in Q4 2025, up 130.12% year-on-year from $7.2 million in Q4 2024, and up 247.75% quarter-over-quarter from $4.8 million in Q3 2025.

Cue Biopharma (CUE) Research & Development (2017 - 2025) Analysis & Trends

Cue Biopharma has disclosed Research & Development across 9 years of filings, most recently posting $16.5 million for Q4 2025.

  • Research & Development for Q4 2025 came in at $16.5 million, up 130.12% year-over-year; the trailing twelve-month figure through Dec 2025 was $37.7 million (up 3.99% YoY), and the FY2025 annual result was $37.7 million, up 3.99% from the prior year.
  • Research & Development came in at $16.5 million for Q4 2025 at Cue Biopharma, up from $4.8 million in the prior quarter.
  • In the past five years, Research & Development ranged from a high of $16.5 million in Q4 2025 to a low of $4.8 million in Q3 2025.
  • The 5-year median for Research & Development is $9.7 million (2021), against an average of $9.7 million.
  • Peak annual rise in Research & Development reached 130.12% in 2025, while the deepest fall reached 49.32% in 2025.
  • Cue Biopharma's Research & Development stood at $11.5 million in 2021, then dropped by 1.47% to $11.3 million in 2022, then decreased by 3.93% to $10.9 million in 2023, then slumped by 34.01% to $7.2 million in 2024, then surged by 130.12% to $16.5 million in 2025.
  • The last three Research & Development figures came in at $16.5 million (Q4 2025), $4.8 million (Q3 2025), and $7.9 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) R&D (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - 4.32 Mn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - 15.66 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 626,092.00
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -101.30 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -2.30 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - 1.46 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - 357,444.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 961.60 Mn
9 Abivax 91.96 Bn 91.96 Bn - -58.00 Mn
10 Cue Biopharma 581.16 Mn 553.47 Mn - 16.53 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 16.53 Mn
Sep 30, 2025 4.75 Mn
Jun 30, 2025 7.91 Mn
Mar 31, 2025 8.55 Mn
Dec 31, 2024 7.18 Mn
Sep 30, 2024 9.38 Mn
Jun 30, 2024 9.53 Mn
Mar 31, 2024 10.20 Mn
Dec 31, 2023 10.89 Mn
Sep 30, 2023 9.87 Mn
Jun 30, 2023 10.65 Mn
Mar 31, 2023 9.39 Mn
Dec 31, 2022 11.33 Mn
Sep 30, 2022 7.57 Mn
Jun 30, 2022 9.59 Mn
Mar 31, 2022 10.08 Mn
Dec 31, 2021 11.50 Mn
Sep 30, 2021 11.29 Mn
Jun 30, 2021 8.76 Mn
Mar 31, 2021 9.82 Mn