Cue Biopharma (CUE) Net Cash Flow (2017 - 2025)

Cue Biopharma's (CUE) quarterly Net Cash Flow came in at $15.4 million in Q4 2025, up 254.96% year-on-year from $4.3 million in Q4 2024, and up 197.75% quarter-over-quarter from -$15.8 million in Q3 2025.

Cue Biopharma (CUE) Net Cash Flow (2017 - 2025) Analysis & Trends

Cue Biopharma has disclosed Net Cash Flow across 9 years of filings, most recently posting $15.4 million for Q4 2025.

  • Net Cash Flow for Q4 2025 came in at $15.4 million, up 254.96% year-over-year; the trailing twelve-month figure through Dec 2025 was $4.7 million (up 117.96% YoY), and the FY2025 annual result was $4.7 million, up 117.96% from the prior year.
  • Net Cash Flow came in at $15.4 million for Q4 2025 at Cue Biopharma, up from -$15.8 million in the prior quarter.
  • In the past five years, Net Cash Flow ranged from a high of $21.9 million in Q4 2022 to a low of -$36.4 million in Q3 2022.
  • The 5-year median for Net Cash Flow is -$2.5 million (2021), against an average of -$2.4 million.
  • Across the five-year window, Net Cash Flow jumped 770.93% in 2022 and tumbled 760.16% in 2025, its largest moves.
  • Cue Biopharma's Net Cash Flow stood at -$3.3 million in 2021, then surged by 770.93% to $21.9 million in 2022, then sank by 128.22% to -$6.2 million in 2023, then tumbled by 61.29% to -$10.0 million in 2024, then jumped by 254.96% to $15.4 million in 2025.
  • The last three Net Cash Flow figures came in at $15.4 million (Q4 2025), -$15.8 million (Q3 2025), and $14.4 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Cash Flow (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 2.44 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 625.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -2.44 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 457.40 Mn
9 Abivax 91.96 Bn 91.96 Bn - 664,983.53
10 Cue Biopharma 581.16 Mn 553.47 Mn - 15.44 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 15.44 Mn
Dec 31, 2025 15.44 Mn
Sep 30, 2025 -15.79 Mn
Sep 30, 2025 -15.79 Mn
Jun 30, 2025 14.36 Mn
Jun 30, 2025 14.36 Mn
Mar 31, 2025 -9.32 Mn
Mar 31, 2025 -9.32 Mn
Dec 31, 2024 -9.96 Mn
Dec 31, 2024 -9.96 Mn
Sep 30, 2024 2.39 Mn
Sep 30, 2024 2.39 Mn
Jun 30, 2024 -11.00 Mn
Jun 30, 2024 -11.00 Mn
Mar 31, 2024 -7.49 Mn
Mar 31, 2024 -7.49 Mn
Dec 31, 2023 -6.18 Mn
Dec 31, 2023 -6.18 Mn
Sep 30, 2023 1.79 Mn
Sep 30, 2023 1.79 Mn