Cue Biopharma CUE
NASDAQ CUE
$23.98 -0.63 (-2.56%)
At close: Aug 21, 2026 · 4:00 PM EDT

Cue Biopharma (CUE) Net Cash Flow (2017 - 2025)

Cue Biopharma (CUE) posted Net Cash Flow of $15.4 million for Q4 2025, up 197.75% sequentially from -$15.8 million in Q3 2025, and up 254.96% YoY from $4.3 million in Q4 2024.

Cue Biopharma (CUE) Net Cash Flow (2017 - 2025) Analysis & Trends

Cue Biopharma has reported Net Cash Flow for 9 years, with the latest figure at $15.4 million in Q4 2025.

  • Quarterly Net Cash Flow rose 254.96% year-over-year to $15.4 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was $4.7 million (up 117.96% YoY) and the FY2025 annual result came in at $4.7 million, up 117.96% from the prior year.
  • Net Cash Flow grew to $15.4 million in Q4 2025 per CUE's latest filing, from -$15.8 million in the prior quarter.
  • Over five years, Net Cash Flow peaked at $21.9 million in Q4 2022 and troughed at -$36.4 million in Q3 2022.
  • A 5-year average of -$2.4 million and a median of -$2.5 million in 2021 frame the typical range for Net Cash Flow.
  • The sharpest annual moves came in 2022 and 2025: Net Cash Flow soared 770.93% in 2022, then tumbled 760.16% in 2025.
  • Over 5 years, Net Cash Flow stood at -$3.3 million in 2021, then jumped by 770.93% to $21.9 million in 2022, then sank by 128.22% to -$6.2 million in 2023, then tumbled by 61.29% to -$10.0 million in 2024, then soared by 254.96% to $15.4 million in 2025.
  • According to Business Quant data, Net Cash Flow over the past three periods registered $15.4 million, -$15.8 million, and $14.4 million for Q4 2025, Q3 2025, and Q2 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Cash Flow (Qtr)
1 Vertex Pharmaceuticals 139.13 Bn 131.28 Bn 2.84 Bn 652.90 Mn
2 Regeneron Pharmaceuticals 85.77 Bn 77.77 Bn 3.93 Bn -504.30 Mn
3 Argenx Se 64.64 Bn 59.46 Bn 1.37 Bn -
4 Moderna 58.29 Bn 53.16 Bn 52.00 Mn -183.00 Mn
5 BeOne Medicines 41.92 Bn 36.82 Bn 1.53 Bn 407.41 Mn
6 Alnylam Pharmaceuticals 31.58 Bn 28.28 Bn 992.69 Mn -496,000.00
7 BioNTech SE 28.12 Bn 9.73 Bn 668.28 Mn -2.83 Bn
8 Insmed 27.39 Bn 26.22 Bn 358.27 Mn -37.14 Mn
9 Royalty Pharma 27.27 Bn 26.43 Bn - 225.59 Mn
10 Cue Biopharma 152.56 Mn 135.14 Mn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 15.44 Mn
Dec 31, 2025 15.44 Mn
Sep 30, 2025 -15.79 Mn
Sep 30, 2025 -15.79 Mn
Jun 30, 2025 14.36 Mn
Jun 30, 2025 14.36 Mn
Mar 31, 2025 -9.32 Mn
Mar 31, 2025 -9.32 Mn
Dec 31, 2024 -9.96 Mn
Dec 31, 2024 -9.96 Mn
Sep 30, 2024 2.39 Mn
Sep 30, 2024 2.39 Mn
Jun 30, 2024 -11.00 Mn
Jun 30, 2024 -11.00 Mn
Mar 31, 2024 -7.49 Mn
Mar 31, 2024 -7.49 Mn
Dec 31, 2023 -6.18 Mn
Dec 31, 2023 -6.18 Mn
Sep 30, 2023 1.79 Mn
Sep 30, 2023 1.79 Mn