Cue Biopharma CUE
NASDAQ CUE
$23.98 -0.63 (-2.56%)
At close: Aug 21, 2026 · 4:00 PM EDT

Cue Biopharma (CUE) Free Cash Flow (2017 - 2025)

Cue Biopharma (CUE) posted Free Cash Flow of -$1.1 million for Q4 2025, up 88.08% sequentially from -$9.0 million in Q3 2025, and up 88.08% YoY from -$572084.3 in Q4 2024.

Cue Biopharma (CUE) Free Cash Flow (2017 - 2025) Analysis & Trends

Cue Biopharma has reported Free Cash Flow for 9 years, with the latest figure at -$1.1 million in Q4 2025.

  • Quarterly Free Cash Flow rose 88.08% year-over-year to -$1.1 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was -$21.9 million (up 39.93% YoY) and the FY2025 annual result came in at -$21.9 million, up 39.93% from the prior year.
  • Free Cash Flow improved to -$1.1 million in Q4 2025 per CUE's latest filing, from -$9.0 million in the prior quarter.
  • Over five years, Free Cash Flow peaked at -$1.1 million in Q4 2025 and troughed at -$12.9 million in Q2 2022.
  • A 5-year average of -$9.0 million and a median of -$9.9 million in 2024 frame the typical range for Free Cash Flow.
  • The widest YoY moves for Free Cash Flow: up 91.79% in 2021, down 107.5% in 2021.
  • Over 5 years, Free Cash Flow stood at -$10.6 million in 2021, then rose by 1.22% to -$10.5 million in 2022, then dropped by 4.21% to -$11.0 million in 2023, then climbed by 17.59% to -$9.0 million in 2024, then jumped by 88.08% to -$1.1 million in 2025.
  • According to Business Quant data, Free Cash Flow over the past three periods registered -$1.1 million, -$9.0 million, and -$3.4 million for Q4 2025, Q3 2025, and Q2 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Vertex Pharmaceuticals 139.13 Bn 131.28 Bn 2.84 Bn 1.01 Bn
2 Regeneron Pharmaceuticals 85.77 Bn 77.77 Bn 3.93 Bn 572.80 Mn
3 Argenx Se 64.64 Bn 59.46 Bn 1.37 Bn -
4 Moderna 58.29 Bn 53.16 Bn 52.00 Mn -563.00 Mn
5 BeOne Medicines 41.92 Bn 36.82 Bn 1.53 Bn 437.80 Mn
6 Alnylam Pharmaceuticals 31.58 Bn 28.28 Bn 992.69 Mn 292.04 Mn
7 BioNTech SE 28.12 Bn 9.73 Bn 668.28 Mn 433.84 Mn
8 Insmed 27.39 Bn 26.22 Bn 358.27 Mn -95.09 Mn
9 Royalty Pharma 27.27 Bn 26.43 Bn - 477.44 Mn
10 Cue Biopharma 152.56 Mn 135.14 Mn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 -1.08 Mn
Dec 31, 2025 -1.08 Mn
Sep 30, 2025 -9.02 Mn
Sep 30, 2025 -9.02 Mn
Jun 30, 2025 -3.44 Mn
Jun 30, 2025 -3.44 Mn
Mar 31, 2025 -8.32 Mn
Mar 31, 2025 -8.32 Mn
Dec 31, 2024 -9.03 Mn
Dec 31, 2024 -9.03 Mn
Sep 30, 2024 -7.53 Mn
Sep 30, 2024 -7.53 Mn
Jun 30, 2024 -10.00 Mn
Jun 30, 2024 -10.00 Mn
Mar 31, 2024 -9.84 Mn
Mar 31, 2024 -9.84 Mn
Dec 31, 2023 -10.96 Mn
Dec 31, 2023 -10.96 Mn
Sep 30, 2023 -7.80 Mn
Sep 30, 2023 -7.80 Mn