Cue Biopharma (CUE) FCF Margin (2018 - 2025)
Cue Biopharma's (CUE) quarterly FCF Margin came in at 11.33% in Q4 2025, up 56164.0% year-over-year from N/an in Q4 2024, and up 97.3% quarter-over-quarter from 419.92% in Q3 2025.
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Cue Biopharma (CUE) FCF Margin (2018 - 2025) Analysis & Trends
Cue Biopharma has disclosed FCF Margin across 8 years of filings, most recently posting 11.33% for Q4 2025.
- In Q4 2025, FCF Margin rose 56164.0% year-over-year to 11.33%; the TTM figure through Dec 2025 stood at 145.53% (up 24636.0% YoY), while the FY2025 annual figure was 79.6%, up 31229.0% from the prior year.
- FCF Margin came in at 11.33% for Q4 2025 at Cue Biopharma, up from 419.92% in the prior quarter.
- In the past five years, FCF Margin ranged from a high of 11.33% in Q4 2025 to a low of 49665.38% in Q2 2022.
- Average FCF Margin over 5 years is 4068.52%, with a median of 573.0% recorded in 2024.
- Year-over-year, FCF Margin plunged 4929948 bps in 2022 and soared 4891495 bps in 2023.
- Over 5 years, FCF Margin stood at 128.96% in 2021, then plunged by 5300 bps to 6963.58% in 2022, then soared by 91 bps to 601.76% in 2023, then increased by 5 bps to 572.97% in 2024, then soared by 98 bps to 11.33% in 2025.
- Per Business Quant data, the three most recent FCF Margin figures were 11.33% in Q4 2025, 419.92% in Q3 2025, and 116.52% in Q2 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | FCF Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Amgen | 206.44 Bn | 192.45 Bn | 7.24 Bn | 34.70% |
| 2 | Gilead Sciences | 179.97 Bn | 176.79 Bn | 6.22 Bn | 44.00% |
| 3 | Vertex Pharmaceuticals | 130.57 Bn | 122.72 Bn | 2.84 Bn | 30.39% |
| 4 | Regeneron Pharmaceuticals | 81.63 Bn | 73.63 Bn | 3.93 Bn | 13.35% |
| 5 | Argenx Se | 60.34 Bn | 55.16 Bn | 1.37 Bn | - |
| 6 | Moderna | 54.37 Bn | 49.23 Bn | 52.00 Mn | -388.28% |
| 7 | Alnylam Pharmaceuticals | 33.07 Bn | 29.76 Bn | 992.69 Mn | 22.62% |
| 8 | Biogen | 31.84 Bn | 30.55 Bn | 1.96 Bn | 14.91% |
| 9 | Roivant Sciences | 29.49 Bn | 29.49 Bn | 1.16 Mn | -18,629.40% |
| 10 | Cue Biopharma | 179.95 Mn | 162.53 Mn | - | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Dec 31, 2025 | -11.33% |
| Sep 30, 2025 | -419.92% |
| Jun 30, 2025 | -116.52% |
| Mar 31, 2025 | -1,976.72% |
| Dec 31, 2024 | -572.97% |
| Sep 30, 2024 | -225.60% |
| Jun 30, 2024 | -376.22% |
| Mar 31, 2024 | -573.03% |
| Dec 31, 2023 | -601.76% |
| Sep 30, 2023 | -371.38% |
| Jun 30, 2023 | -750.43% |
| Mar 31, 2023 | -5,793.05% |
| Dec 31, 2022 | -6,963.58% |
| Sep 30, 2022 | -10,219.12% |
| Jun 30, 2022 | -49,665.38% |
| Mar 31, 2022 | -1,160.00% |
| Dec 31, 2021 | -128.96% |
| Sep 30, 2021 | -277.24% |
| Jun 30, 2021 | -365.90% |
| Mar 31, 2021 | -801.22% |