Cue Biopharma (CUE) FCF Margin (2018 - 2025)

Cue Biopharma's (CUE) quarterly FCF Margin came in at 11.33% in Q4 2025, up 56164.0% year-on-year from N/an in Q4 2024, and up 97.3% quarter-over-quarter from 419.92% in Q3 2025.

Cue Biopharma (CUE) FCF Margin (2018 - 2025) Analysis & Trends

Cue Biopharma has disclosed FCF Margin across 8 years of filings, most recently posting 11.33% for Q4 2025.

  • FCF Margin for Q4 2025 came in at 11.33%, up 56164.0% year-over-year; the trailing twelve-month figure through Dec 2025 was 145.53% (up 24636.0% YoY), and the FY2025 annual result was 79.6%, up 31229.0% from the prior year.
  • FCF Margin came in at 11.33% for Q4 2025 at Cue Biopharma, up from 419.92% in the prior quarter.
  • In the past five years, FCF Margin ranged from a high of 11.33% in Q4 2025 to a low of 49665.38% in Q2 2022.
  • The 5-year median for FCF Margin is 573.0% (2024), against an average of 4068.52%.
  • Across the five-year window, FCF Margin sank 4929948 bps in 2022 and surged 4891495 bps in 2023, its largest moves.
  • Cue Biopharma's FCF Margin stood at 128.96% in 2021, then slumped by 5300 bps to 6963.58% in 2022, then soared by 91 bps to 601.76% in 2023, then increased by 5 bps to 572.97% in 2024, then soared by 98 bps to 11.33% in 2025.
  • The last three FCF Margin figures came in at 11.33% (Q4 2025), 419.92% (Q3 2025), and 116.52% (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) FCF Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -3.98%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 43.35%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Cue Biopharma 581.16 Mn 553.47 Mn - -11.33%

Historic Data

Download Data
DateValue
Dec 31, 2025 -11.33%
Sep 30, 2025 -419.92%
Jun 30, 2025 -116.52%
Mar 31, 2025 -1,976.72%
Dec 31, 2024 -572.97%
Sep 30, 2024 -225.60%
Jun 30, 2024 -376.22%
Mar 31, 2024 -573.03%
Dec 31, 2023 -601.76%
Sep 30, 2023 -371.38%
Jun 30, 2023 -750.43%
Mar 31, 2023 -5,793.05%
Dec 31, 2022 -6,963.58%
Sep 30, 2022 -10,219.12%
Jun 30, 2022 -49,665.38%
Mar 31, 2022 -1,160.00%
Dec 31, 2021 -128.96%
Sep 30, 2021 -277.24%
Jun 30, 2021 -365.90%
Mar 31, 2021 -801.22%