Growth Metrics

Cue Biopharma (CUE) Enterprise Value (2017 - 2025)

Cue Biopharma recorded quarterly Enterprise Value of -$27.7 million in Q4 2025, down 52.16% quarter-over-quarter from -$18.2 million in Q3 2025, and down 18.41% year-over-year from -$33.9 million in Q4 2024.

Cue Biopharma's Enterprise Value history runs 9 years deep, the most recent figure standing at -$27.7 million for Q4 2025.

  • In Q4 2025, Enterprise Value fell 18.41% year-over-year to -$27.7 million; the TTM figure through Dec 2025 stood at -$27.7 million (down 18.41% YoY), while the FY2025 annual figure was -$27.7 million, down 18.41% from the prior year.
  • Enterprise Value came in at -$27.7 million for Q4 2025 at Cue Biopharma, down from -$18.2 million in the prior quarter.
  • In the past five years, Enterprise Value ranged from a high of -$14.0 million in Q1 2025 to a low of -$76.3 million in Q4 2022.
  • A 5-year average of -$48.9 million and a median of -$53.4 million in 2021 frame the typical range for Enterprise Value.
  • Across the five-year window, Enterprise Value sank 50.33% in 2021 and soared 65.76% in 2025, its largest moves.
  • Cue Biopharma's Enterprise Value stood at -$52.2 million in 2021, then slumped by 46.12% to -$76.3 million in 2022, then jumped by 36.03% to -$48.8 million in 2023, then jumped by 52.07% to -$23.4 million in 2024, then dropped by 18.41% to -$27.7 million in 2025.
  • According to Business Quant data, Enterprise Value over the past three periods registered -$27.7 million, -$18.2 million, and -$28.0 million for Q4 2025, Q3 2025, and Q2 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -2.32 Mn
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -32.30 Mn
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -286.70 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -61.46 Mn
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -2.77 Mn
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn -7.25 Bn
7 Evaxion A 64.16 Bn 64.14 Bn - -18.44 Mn
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn -8.75 Bn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn -3.01 Bn
10 Cue Biopharma 449.73 Mn 422.04 Mn - -27.69 Mn

Historic Data

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DateValue
Dec 31, 2025 -27.69 Mn
Sep 30, 2025 -18.20 Mn
Jun 30, 2025 -27.96 Mn
Mar 31, 2025 -14.05 Mn
Dec 31, 2024 -23.39 Mn
Sep 30, 2024 -32.42 Mn
Jun 30, 2024 -30.03 Mn
Mar 31, 2024 -41.03 Mn
Dec 31, 2023 -48.80 Mn
Sep 30, 2023 -54.69 Mn
Jun 30, 2023 -57.89 Mn
Mar 31, 2023 -66.20 Mn
Dec 31, 2022 -76.29 Mn
Sep 30, 2022 -59.18 Mn
Jun 30, 2022 -66.13 Mn
Mar 31, 2022 -67.93 Mn
Dec 31, 2021 -52.21 Mn
Sep 30, 2021 -67.63 Mn
Jun 30, 2021 -73.92 Mn
Mar 31, 2021 -73.26 Mn
Dec 31, 2020 -84.87 Mn
Sep 30, 2020 -91.80 Mn
Mar 31, 2020 -48.73 Mn
Dec 31, 2019 -59.41 Mn
Sep 30, 2019 -31.38 Mn
Jun 30, 2019 -28.26 Mn
Mar 31, 2019 -21.96 Mn
Dec 31, 2018 -39.21 Mn
Sep 30, 2018 -39.18 Mn
Jun 30, 2018 -45.79 Mn
Mar 31, 2018 -53.15 Mn
Dec 31, 2017 -63.58 Mn
Sep 30, 2017 -3.40 Mn
Jun 30, 2017 -7.36 Mn
Mar 31, 2017 -10.91 Mn