CytomX Therapeutics (CTMX) Operating Income (2014 - 2026)

CytomX Therapeutics (CTMX) reported Operating Income of -$19.7 million for Q1 2026, down 186.96% on a YoY basis from $22.6 million in Q1 2025, and down 114.62% quarter-over-quarter from -$9.2 million in Q4 2025.

CytomX Therapeutics (CTMX) Operating Income (2014 - 2026) Analysis & Trends

CytomX Therapeutics has reported Operating Income for 13 years, with the latest figure at -$19.7 million in Q1 2026.

  • For the quarter ending Q1 2026, Operating Income fell 186.96% year-over-year to -$19.7 million; the trailing twelve-month figure through Mar 2026 stood at -$45.9 million (down 227.62% YoY), and the FY2025 full-year result was -$3.6 million, down 114.39% from the prior year.
  • Operating Income for Q1 2026 stood at -$19.7 million, down from -$9.2 million in the prior quarter.
  • The five-year high for Operating Income was $22.6 million in Q1 2025, with the low at -$32.1 million in Q1 2022.
  • Historically, Operating Income has averaged -$6.2 million across 5 years, with a median of -$5.7 million in 2023.
  • Annual changes were most pronounced in 2024 — Operating Income surged 3017.33% — and 2025, when it tumbled 483.56%.
  • CytomX Therapeutics' Operating Income stood at -$9.5 million in 2022, then jumped by 93.63% to -$606000.0 in 2023, then surged by 3017.33% to $17.7 million in 2024, then tumbled by 151.85% to -$9.2 million in 2025, then plunged by 114.62% to -$19.7 million in 2026.
  • The last three Operating Income figures came in at -$19.7 million (Q1 2026), -$9.2 million (Q4 2025), and -$15.8 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -32.68 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -15.76 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 CytomX Therapeutics 520.30 Mn 173.59 Mn - -19.67 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -19.67 Mn
Dec 31, 2025 -9.17 Mn
Sep 30, 2025 -15.77 Mn
Jun 30, 2025 -1.29 Mn
Mar 31, 2025 22.62 Mn
Dec 31, 2024 17.68 Mn
Sep 30, 2024 4.11 Mn
Jun 30, 2024 -8.45 Mn
Mar 31, 2024 11.66 Mn
Dec 31, 2023 -606,000.00
Sep 30, 2023 3.12 Mn
Jun 30, 2023 -3.35 Mn
Mar 31, 2023 -5.65 Mn
Dec 31, 2022 -9.51 Mn
Sep 30, 2022 -29.71 Mn
Jun 30, 2022 -30.05 Mn
Mar 31, 2022 -32.06 Mn
Dec 31, 2021 -34.90 Mn
Sep 30, 2021 -31.04 Mn
Jun 30, 2021 -26.70 Mn