CytomX Therapeutics (CTMX) Net Margin (2014 - 2026)

CytomX Therapeutics' (CTMX) quarterly Net Margin came in at 177.89% in Q1 2026, down 22409.0% YoY from N/an in Q1 2025, and up 94.8% on a QoQ basis from 3419.91% in Q4 2025.

CytomX Therapeutics (CTMX) Net Margin (2014 - 2026) Analysis & Trends

CytomX Therapeutics (CTMX) has 13 years of Net Margin data on file, last reported at 177.89% in Q1 2026.

  • Quarterly Net Margin fell 22409.0% year-over-year to 177.89% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 155.6% (down 18380.0% YoY) and the FY2025 annual result came in at 26.73%, down 4981.0% from the prior year.
  • Net Margin climbed to 177.89% in Q1 2026, from 3419.91% in the prior quarter.
  • In the past five years, Net Margin ranged from a high of 49.55% in Q4 2024 to a low of 3419.91% in Q4 2025.
  • A 5-year average of 271.1% and a median of 14.09% in 2023 frame the typical range for Net Margin.
  • Annual changes were most pronounced in 2023 — Net Margin jumped 33968 bps — and 2025, when it slumped 346946 bps.
  • Tracing CTMX's Net Margin over 5 years: stood at 43.61% in 2022, then surged by 107 bps to 3.15% in 2023, then soared by 1475 bps to 49.55% in 2024, then sank by 7002 bps to 3419.91% in 2025, then soared by 95 bps to 177.89% in 2026.
  • The last three Net Margin figures came in at 177.89% (Q1 2026), 3419.91% (Q4 2025), and 238.62% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 32.99%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 30.23%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 30.33%
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 13.90%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 30.98%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 12.09%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 12.74%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -3.12%
10 CytomX Therapeutics 732.14 Mn 401.86 Mn - -1,457.40%

Historic Data

Download Data
DateValue
Jun 30, 2026 -1,457.40%
Mar 31, 2026 -177.89%
Dec 31, 2025 -3,419.91%
Sep 30, 2025 -238.62%
Jun 30, 2025 -0.83%
Mar 31, 2025 46.20%
Dec 31, 2024 49.55%
Sep 30, 2024 17.16%
Jun 30, 2024 -26.02%
Mar 31, 2024 33.26%
Dec 31, 2023 3.15%
Sep 30, 2023 11.34%
Jun 30, 2023 -4.40%
Mar 31, 2023 -14.09%
Dec 31, 2022 -43.61%
Sep 30, 2022 -260.73%
Jun 30, 2022 -229.49%
Mar 31, 2022 -353.77%
Dec 31, 2021 -312.82%
Sep 30, 2021 -337.16%