CytomX Therapeutics (CTMX) Net Margin (2014 - 2026)
CytomX Therapeutics (CTMX) posted Net Margin of 177.89% for Q1 2026, up 94.8% on a QoQ basis from 3419.91% in Q4 2025, and down 22409.0% year-over-year from N/an in Q1 2025.
CytomX Therapeutics (CTMX) Net Margin (2014 - 2026) Analysis & Trends
CytomX Therapeutics' Net Margin history runs 13 years deep, the most recent figure standing at 177.89% for Q1 2026.
- Quarterly Net Margin fell 22409.0% year-over-year to 177.89% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 155.6% (down 18380.0% YoY) and the FY2025 annual result came in at 26.73%, down 4981.0% from the prior year.
- Net Margin was 177.89% for Q1 2026 at CytomX Therapeutics, up from 3419.91% in the prior quarter.
- Across five years, Net Margin topped out at 49.55% in Q4 2024 and bottomed at 3419.91% in Q4 2025.
- A 5-year average of 271.1% and a median of 14.09% in 2023 frame the typical range for Net Margin.
- Annual changes were most pronounced in 2023 — Net Margin jumped 33968 bps — and 2025, when it sank 346946 bps.
- CytomX Therapeutics' Net Margin stood at 43.61% in 2022, then jumped by 107 bps to 3.15% in 2023, then surged by 1475 bps to 49.55% in 2024, then tumbled by 7002 bps to 3419.91% in 2025, then surged by 95 bps to 177.89% in 2026.
- Business Quant data shows CTMX's Net Margin at 177.89% in Q1 2026, 3419.91% in Q4 2025, and 238.62% in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | - |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 15.02% |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 34.53% |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 20.17% |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 30.33% |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | - |
| 10 | CytomX Therapeutics | 590.32 Mn | 243.61 Mn | - | -177.89% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -177.89% |
| Dec 31, 2025 | -3,419.91% |
| Sep 30, 2025 | -238.62% |
| Jun 30, 2025 | -0.83% |
| Mar 31, 2025 | 46.20% |
| Dec 31, 2024 | 49.55% |
| Sep 30, 2024 | 17.16% |
| Jun 30, 2024 | -26.02% |
| Mar 31, 2024 | 33.26% |
| Dec 31, 2023 | 3.15% |
| Sep 30, 2023 | 11.34% |
| Jun 30, 2023 | -4.40% |
| Mar 31, 2023 | -14.09% |
| Dec 31, 2022 | -43.61% |
| Sep 30, 2022 | -260.73% |
| Jun 30, 2022 | -229.49% |
| Mar 31, 2022 | -353.77% |
| Dec 31, 2021 | -312.82% |
| Sep 30, 2021 | -337.16% |
| Jun 30, 2021 | -303.99% |