Growth Metrics

CytomX Therapeutics (CTMX) EBITDA Margin (2016 - 2025)

CytomX Therapeutics' EBITDA Margin history spans 12 years, with the latest figure at 1382.5% for Q4 2025.

  • For Q4 2025, EBITDA Margin fell 143202.0% year-over-year to 1382.5%; the TTM value through Dec 2025 reached 0.07%, down 2296.0%, while the annual FY2025 figure was 4.72%, 2775.0% down from the prior year.
  • EBITDA Margin reached 1382.5% in Q4 2025 per CTMX's latest filing, down from 237.43% in the prior quarter.
  • In the past five years, EBITDA Margin ranged from a high of 49.52% in Q4 2024 to a low of 1382.5% in Q4 2025.
  • Average EBITDA Margin over 5 years is 181.7%, with a median of 32.8% recorded in 2022.
  • Peak YoY movement for EBITDA Margin: skyrocketed 34724bps in 2023, then crashed -143202bps in 2025.
  • A 5-year view of EBITDA Margin shows it stood at 315.46% in 2021, then surged by 87bps to 39.61% in 2022, then surged by 109bps to 3.74% in 2023, then skyrocketed by 1224bps to 49.52% in 2024, then plummeted by -2892bps to 1382.5% in 2025.
  • Per Business Quant, the three most recent readings for CTMX's EBITDA Margin are 1382.5% (Q4 2025), 237.43% (Q3 2025), and 0.64% (Q2 2025).