CytomX Therapeutics (CTMX) EBITDA Margin (2014 - 2026)

CytomX Therapeutics (CTMX) reported EBITDA Margin of 177.98% for Q1 2026, down 22413.0% on a YoY basis from N/an in Q1 2025, and up 87.13% quarter-over-quarter from 1382.5% in Q4 2025.

CytomX Therapeutics (CTMX) EBITDA Margin (2014 - 2026) Analysis & Trends

CytomX Therapeutics has reported EBITDA Margin for 13 years, with the latest figure at 177.98% in Q1 2026.

  • For the quarter ending Q1 2026, EBITDA Margin fell 22413.0% year-over-year to 177.98%; the trailing twelve-month figure through Mar 2026 stood at 117.33% (down 14553.0% YoY), and the FY2025 full-year result was 4.72%, down 2775.0% from the prior year.
  • EBITDA Margin for Q1 2026 stood at 177.98%, up from 1382.5% in the prior quarter.
  • The five-year high for EBITDA Margin was 49.52% in Q4 2024, with the low at 1382.5% in Q4 2025.
  • Historically, EBITDA Margin has averaged 151.29% across 5 years, with a median of 14.02% in 2023.
  • Annual changes were most pronounced in 2023 — EBITDA Margin soared 34724 bps — and 2025, when it plunged 143202 bps.
  • CytomX Therapeutics' EBITDA Margin stood at 39.61% in 2022, then soared by 109 bps to 3.74% in 2023, then surged by 1224 bps to 49.52% in 2024, then sank by 2892 bps to 1382.5% in 2025, then surged by 87 bps to 177.98% in 2026.
  • The last three EBITDA Margin figures came in at 177.98% (Q1 2026), 1382.5% (Q4 2025), and 237.43% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -6.43%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 38.10%
9 Abivax 91.96 Bn 91.96 Bn - -
10 CytomX Therapeutics 520.30 Mn 173.59 Mn - -177.98%

Historic Data

Download Data
DateValue
Mar 31, 2026 -177.98%
Dec 31, 2025 -1,382.50%
Sep 30, 2025 -237.43%
Jun 30, 2025 -0.64%
Mar 31, 2025 46.15%
Dec 31, 2024 49.52%
Sep 30, 2024 17.29%
Jun 30, 2024 -25.99%
Mar 31, 2024 33.01%
Dec 31, 2023 3.74%
Sep 30, 2023 10.97%
Jun 30, 2023 -4.36%
Mar 31, 2023 -14.02%
Dec 31, 2022 -39.61%
Sep 30, 2022 -257.44%
Jun 30, 2022 -231.38%
Mar 31, 2022 -361.26%
Dec 31, 2021 -315.46%
Sep 30, 2021 -336.76%
Jun 30, 2021 -303.33%