Growth Metrics

CRISPR Therapeutics AG (CRSP) Return on Invested Capital (2016 - 2025)

CRISPR Therapeutics AG's Return on Invested Capital history spans 10 years, with the latest figure at 0.35% for Q4 2025.

  • For Q4 2025, Return on Invested Capital fell 13.0% year-over-year to 0.35%; the TTM value through Dec 2025 reached 0.35%, down 13.0%, while the annual FY2025 figure was 0.35%, 13.0% down from the prior year.
  • Return on Invested Capital for Q4 2025 was 0.35% at CRISPR Therapeutics AG, down from 0.33% in the prior quarter.
  • Across five years, Return on Invested Capital topped out at 0.2% in Q2 2021 and bottomed at 0.35% in Q4 2022.
  • The 5-year median for Return on Invested Capital is 0.22% (2021), against an average of 0.17%.
  • The largest annual shift saw Return on Invested Capital skyrocketed 39bps in 2021 before it tumbled -50bps in 2022.
  • A 5-year view of Return on Invested Capital shows it stood at 0.15% in 2021, then tumbled by -331bps to 0.35% in 2022, then soared by 69bps to 0.11% in 2023, then tumbled by -98bps to 0.22% in 2024, then tumbled by -60bps to 0.35% in 2025.
  • Per Business Quant, the three most recent readings for CRSP's Return on Invested Capital are 0.35% (Q4 2025), 0.33% (Q3 2025), and 0.34% (Q2 2025).