Crinetics Pharmaceuticals (CRNX) Return on Equity [ROE] (2018 - 2026)
Crinetics Pharmaceuticals' Return on Equity [ROE] came in at -40.51% for Q2 2026, down 45.05 percentage points from 4.53% a year earlier and down 17.21 percentage points from the prior quarter.
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Analysis
Crinetics Pharmaceuticals (CRNX) Return on Equity [ROE] (2018 - 2026) Analysis & Trends
For FY2025, Crinetics Pharmaceuticals' Return on Equity [ROE] was -40.17%, down 8.20 percentage points from FY2024.
- Return on Equity [ROE] carries a five-year change of +11.44 percentage points (FY2020 to FY2025).
- Going back by year, Return on Equity [ROE] was -31.97% in FY2024 (+16.97 pp), -48.94% in FY2023 (-99.20 pp), 50.26% in FY2022 (+93.24 pp) and -42.98% in FY2021 (+8.62 pp).
- The Q2 2026 figure represents the lowest quarterly Return on Equity [ROE] since Q4 2021.
- Year-over-year, Return on Equity [ROE] has declined for three consecutive quarters, with an average year-over-year change of -4.05 percentage points over the last eight quarters.
- The fastest year-over-year change in Return on Equity [ROE] over five years came in Q2 2023 (a gain of 92.22 percentage points), and the weakest in Q2 2024 (a drop of 88.25 percentage points).
- Business Quant data shows CRNX's Return on Equity [ROE] at -23.30% (Q1 2026), -3.91% (Q4 2025) and 0.15% (Q3 2025) in the three quarters before Q2 2026.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 25.32% |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | - |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | 7.21% |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 84.40% |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | 21.39% |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 83.75% |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | -18.38% |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | 4.97% |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 22.24% |
| 10 | Crinetics Pharmaceuticals | 8.99 Bn | 8.99 Bn | 24.96 Mn | -40.51% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -40.51% |
| Mar 31, 2026 | -23.30% |
| Dec 31, 2025 | -3.91% |
| Sep 30, 2025 | 0.15% |
| Jun 30, 2025 | 4.53% |
| Mar 31, 2025 | 1.04% |
| Dec 31, 2024 | -1.57% |
| Sep 30, 2024 | -35.95% |
| Jun 30, 2024 | -19.44% |
| Mar 31, 2024 | -26.71% |
| Dec 31, 2023 | -38.52% |
| Sep 30, 2023 | 49.49% |
| Jun 30, 2023 | 68.82% |
| Mar 31, 2023 | 58.76% |
| Dec 31, 2022 | 48.80% |
| Sep 30, 2022 | -18.05% |
| Jun 30, 2022 | -23.40% |
| Mar 31, 2022 | -30.53% |
| Dec 31, 2021 | -40.96% |
| Sep 30, 2021 | 27.90% |
API Access
Crinetics Pharmaceuticals Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=CRNX&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "CRNX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=CRNX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();