Crinetics Pharmaceuticals (CRNX) Operating Income (2017 - 2026)
Crinetics Pharmaceuticals (CRNX) recorded quarterly Operating Income of -$140.4 million in Q1 2026, down 5.02% quarter-over-quarter from -$133.7 million in Q4 2025, and down 26.01% on a YoY basis from -$189.7 million in Q1 2025.
Crinetics Pharmaceuticals (CRNX) Operating Income (2017 - 2026) Analysis & Trends
Crinetics Pharmaceuticals' Operating Income history runs 10 years deep, the most recent figure standing at -$140.4 million for Q1 2026.
- In Q1 2026, Operating Income fell 26.01% year-over-year to -$140.4 million; the TTM figure through Mar 2026 stood at -$545.7 million (down 44.86% YoY), while the FY2025 annual figure was -$516.8 million, down 52.5% from the prior year.
- Operating Income was -$140.4 million for Q1 2026 at Crinetics Pharmaceuticals, down from -$133.7 million in the prior quarter.
- In the past five years, Operating Income ranged from a high of -$33.8 million in Q1 2022 to a low of -$142.6 million in Q3 2025.
- Historically, Operating Income has averaged -$81.6 million across 5 years, with a median of -$73.5 million in 2024.
- The sharpest annual moves came in 2022 and 2023: Operating Income tumbled 64.99% in 2022, then slipped 23.12% in 2023.
- A 5-year view of Operating Income shows it stood at -$47.6 million in 2022, then sank by 31.76% to -$62.7 million in 2023, then sank by 51.21% to -$94.7 million in 2024, then sank by 41.08% to -$133.7 million in 2025, then dropped by 5.02% to -$140.4 million in 2026.
- The last three Operating Income figures came in at -$140.4 million (Q1 2026), -$133.7 million (Q4 2025), and -$142.6 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | -32.68 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -2.97 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -15.76 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -65.83 Mn |
| 10 | Crinetics Pharmaceuticals | 3.75 Bn | 3.75 Bn | 10.53 Mn | -140.38 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -140.38 Mn |
| Dec 31, 2025 | -133.67 Mn |
| Sep 30, 2025 | -142.59 Mn |
| Jun 30, 2025 | -129.11 Mn |
| Mar 31, 2025 | -111.41 Mn |
| Dec 31, 2024 | -94.75 Mn |
| Sep 30, 2024 | -87.80 Mn |
| Jun 30, 2024 | -82.78 Mn |
| Mar 31, 2024 | -73.53 Mn |
| Dec 31, 2023 | -62.66 Mn |
| Sep 30, 2023 | -58.98 Mn |
| Jun 30, 2023 | -53.00 Mn |
| Mar 31, 2023 | -47.98 Mn |
| Dec 31, 2022 | -47.56 Mn |
| Sep 30, 2022 | -43.45 Mn |
| Jun 30, 2022 | -43.05 Mn |
| Mar 31, 2022 | -33.83 Mn |
| Dec 31, 2021 | -30.89 Mn |
| Sep 30, 2021 | -27.81 Mn |
| Jun 30, 2021 | -26.09 Mn |