Crinetics Pharmaceuticals (CRNX) EBITDA (2017 - 2026)
Crinetics Pharmaceuticals (CRNX) recorded quarterly EBITDA of -$131.0 million in Q1 2026, down 6.35% quarter-over-quarter from -$123.1 million in Q4 2025, and down 36.8% on a YoY basis from -$207.2 million in Q1 2025.
Crinetics Pharmaceuticals (CRNX) EBITDA (2017 - 2026) Analysis & Trends
Crinetics Pharmaceuticals' EBITDA history runs 10 years deep, the most recent figure standing at -$131.0 million for Q1 2026.
- In Q1 2026, EBITDA fell 36.8% year-over-year to -$131.0 million; the TTM figure through Mar 2026 stood at -$499.6 million (down 53.08% YoY), while the FY2025 annual figure was -$464.4 million, down 55.62% from the prior year.
- EBITDA was -$131.0 million for Q1 2026 at Crinetics Pharmaceuticals, down from -$123.1 million in the prior quarter.
- In the past five years, EBITDA ranged from a high of -$36.4 million in Q1 2022 to a low of -$131.0 million in Q1 2026.
- Historically, EBITDA has averaged -$74.8 million across 5 years, with a median of -$67.8 million in 2024.
- The sharpest annual moves came in 2023 and 2025: EBITDA dropped 14.54% in 2023, then tumbled 73.62% in 2025.
- A 5-year view of EBITDA shows it stood at -$43.9 million in 2022, then sank by 32.66% to -$58.3 million in 2023, then sank by 40.19% to -$81.7 million in 2024, then plunged by 50.78% to -$123.1 million in 2025, then declined by 6.35% to -$131.0 million in 2026.
- The last three EBITDA figures came in at -$131.0 million (Q1 2026), -$123.1 million (Q4 2025), and -$129.5 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | -26.92 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -13.63 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -14.44 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | -752,618.00 |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -65.83 Mn |
| 10 | Crinetics Pharmaceuticals | 3.75 Bn | 3.75 Bn | 10.53 Mn | -130.96 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -130.96 Mn |
| Dec 31, 2025 | -123.14 Mn |
| Sep 30, 2025 | -129.52 Mn |
| Jun 30, 2025 | -116.02 Mn |
| Mar 31, 2025 | -95.74 Mn |
| Dec 31, 2024 | -81.67 Mn |
| Sep 30, 2024 | -74.60 Mn |
| Jun 30, 2024 | -74.40 Mn |
| Mar 31, 2024 | -67.76 Mn |
| Dec 31, 2023 | -58.26 Mn |
| Sep 30, 2023 | -56.62 Mn |
| Jun 30, 2023 | -50.17 Mn |
| Mar 31, 2023 | -44.58 Mn |
| Dec 31, 2022 | -43.91 Mn |
| Sep 30, 2022 | -43.32 Mn |
| Jun 30, 2022 | -43.80 Mn |
| Mar 31, 2022 | -36.44 Mn |
| Dec 31, 2021 | -31.16 Mn |
| Sep 30, 2021 | -27.87 Mn |
| Jun 30, 2021 | -26.10 Mn |