Crinetics Pharmaceuticals CRNX
NASDAQ CRNX
$84.95 +0.00 (+0.00%)
At close: Sep 2, 2026 · 4:00 PM EDT

Crinetics Pharmaceuticals (CRNX) EBITDA (2017 - 2026)

Crinetics Pharmaceuticals (CRNX) posted quarterly EBITDA of -$140.4 million for Q1 2026, down 26.01% year-over-year from -$189.7 million in Q1 2025, and down 5.02% quarter-over-quarter from -$133.7 million in Q4 2025.

Analysis

Crinetics Pharmaceuticals (CRNX) EBITDA (2017 - 2026) Analysis & Trends

Crinetics Pharmaceuticals' EBITDA history runs 10 years deep, the most recent figure standing at -$140.4 million for Q1 2026.

  • In Q1 2026, EBITDA fell 26.01% year-over-year to -$140.4 million; the TTM figure through Mar 2026 stood at -$545.7 million (down 44.86% YoY), while the FY2025 annual figure was -$516.8 million, down 52.5% from the prior year.
  • EBITDA for Q1 2026 stood at -$140.4 million, down from -$133.7 million in the prior quarter.
  • The five-year high for EBITDA was -$33.8 million in Q1 2022, with the low at -$142.6 million in Q3 2025.
  • The 5-year median for EBITDA is -$73.5 million (2024), against an average of -$81.6 million.
  • The sharpest annual moves came in 2022 and 2023: EBITDA slumped 64.99% in 2022, then decreased 23.12% in 2023.
  • Crinetics Pharmaceuticals' EBITDA stood at -$47.6 million in 2022, then plunged by 31.76% to -$62.7 million in 2023, then plunged by 51.21% to -$94.7 million in 2024, then plunged by 41.08% to -$133.7 million in 2025, then slipped by 5.02% to -$140.4 million in 2026.
  • Business Quant data shows CRNX's EBITDA at -$140.4 million in Q1 2026, -$133.7 million in Q4 2025, and -$142.6 million in Q3 2025.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Vertex Pharmaceuticals 138.78 Bn 130.92 Bn 2.84 Bn 1.25 Bn
2 Regeneron Pharmaceuticals 85.50 Bn 77.51 Bn 3.93 Bn 1.29 Bn
3 Argenx Se 63.51 Bn 58.32 Bn 1.37 Bn 493.00 Mn
4 Moderna 58.06 Bn 52.92 Bn 52.00 Mn -815.00 Mn
5 Revolution Medicines 44.04 Bn 44.04 Bn - -505.13 Mn
6 BeOne Medicines 40.04 Bn 34.94 Bn 1.53 Bn 325.05 Mn
7 Alnylam Pharmaceuticals 35.45 Bn 32.14 Bn 992.69 Mn 231.44 Mn
8 Royalty Pharma 28.41 Bn 27.57 Bn - 133.12 Mn
9 Insmed 27.42 Bn 26.26 Bn 358.27 Mn -1.55 Mn
10 Crinetics Pharmaceuticals 8.99 Bn 8.99 Bn 24.96 Mn -132.46 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -132.46 Mn
Mar 31, 2026 -140.38 Mn
Dec 31, 2025 -133.67 Mn
Sep 30, 2025 -142.59 Mn
Jun 30, 2025 -129.11 Mn
Mar 31, 2025 -111.41 Mn
Dec 31, 2024 -94.75 Mn
Sep 30, 2024 -87.80 Mn
Jun 30, 2024 -82.78 Mn
Mar 31, 2024 -73.53 Mn
Dec 31, 2023 -62.66 Mn
Sep 30, 2023 -58.98 Mn
Jun 30, 2023 -53.00 Mn
Mar 31, 2023 -47.98 Mn
Dec 31, 2022 -47.56 Mn
Sep 30, 2022 -43.45 Mn
Jun 30, 2022 -43.05 Mn
Mar 31, 2022 -33.83 Mn
Dec 31, 2021 -30.89 Mn
Sep 30, 2021 -27.81 Mn