Crinetics Pharmaceuticals (CRNX) EBITDA (2017 - 2026)

Crinetics Pharmaceuticals (CRNX) recorded quarterly EBITDA of -$131.0 million in Q1 2026, down 6.35% quarter-over-quarter from -$123.1 million in Q4 2025, and down 36.8% on a YoY basis from -$207.2 million in Q1 2025.

Crinetics Pharmaceuticals (CRNX) EBITDA (2017 - 2026) Analysis & Trends

Crinetics Pharmaceuticals' EBITDA history runs 10 years deep, the most recent figure standing at -$131.0 million for Q1 2026.

  • In Q1 2026, EBITDA fell 36.8% year-over-year to -$131.0 million; the TTM figure through Mar 2026 stood at -$499.6 million (down 53.08% YoY), while the FY2025 annual figure was -$464.4 million, down 55.62% from the prior year.
  • EBITDA was -$131.0 million for Q1 2026 at Crinetics Pharmaceuticals, down from -$123.1 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of -$36.4 million in Q1 2022 to a low of -$131.0 million in Q1 2026.
  • Historically, EBITDA has averaged -$74.8 million across 5 years, with a median of -$67.8 million in 2024.
  • The sharpest annual moves came in 2023 and 2025: EBITDA dropped 14.54% in 2023, then tumbled 73.62% in 2025.
  • A 5-year view of EBITDA shows it stood at -$43.9 million in 2022, then sank by 32.66% to -$58.3 million in 2023, then sank by 40.19% to -$81.7 million in 2024, then plunged by 50.78% to -$123.1 million in 2025, then declined by 6.35% to -$131.0 million in 2026.
  • The last three EBITDA figures came in at -$131.0 million (Q1 2026), -$123.1 million (Q4 2025), and -$129.5 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -26.92 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -13.63 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -14.44 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -752,618.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Crinetics Pharmaceuticals 3.75 Bn 3.75 Bn 10.53 Mn -130.96 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -130.96 Mn
Dec 31, 2025 -123.14 Mn
Sep 30, 2025 -129.52 Mn
Jun 30, 2025 -116.02 Mn
Mar 31, 2025 -95.74 Mn
Dec 31, 2024 -81.67 Mn
Sep 30, 2024 -74.60 Mn
Jun 30, 2024 -74.40 Mn
Mar 31, 2024 -67.76 Mn
Dec 31, 2023 -58.26 Mn
Sep 30, 2023 -56.62 Mn
Jun 30, 2023 -50.17 Mn
Mar 31, 2023 -44.58 Mn
Dec 31, 2022 -43.91 Mn
Sep 30, 2022 -43.32 Mn
Jun 30, 2022 -43.80 Mn
Mar 31, 2022 -36.44 Mn
Dec 31, 2021 -31.16 Mn
Sep 30, 2021 -27.87 Mn
Jun 30, 2021 -26.10 Mn