Crinetics Pharmaceuticals (CRNX) EBIT (2017 - 2026)

Crinetics Pharmaceuticals' (CRNX) quarterly EBIT came in at -$140.4 million in Q1 2026, down 26.01% year-on-year from -$189.7 million in Q1 2025, and down 5.02% quarter-over-quarter from -$133.7 million in Q4 2025.

Crinetics Pharmaceuticals (CRNX) EBIT (2017 - 2026) Analysis & Trends

Crinetics Pharmaceuticals' EBIT history runs 10 years deep, the most recent figure standing at -$140.4 million for Q1 2026.

  • On a quarterly basis, EBIT fell 26.01% year-over-year to -$140.4 million in Q1 2026; TTM through Mar 2026 was -$545.7 million, a 44.86% decrease from a year earlier, with the FY2025 full-year figure at -$516.8 million, down 52.5% from the prior year.
  • EBIT fell to -$140.4 million in Q1 2026 per CRNX's latest filing, from -$133.7 million in the prior quarter.
  • Across five years, EBIT topped out at -$33.8 million in Q1 2022 and bottomed at -$142.6 million in Q3 2025.
  • The 5-year median for EBIT is -$73.5 million (2024), against an average of -$81.6 million.
  • Across the five-year window, EBIT tumbled 64.99% in 2022 and declined 23.12% in 2023, its largest moves.
  • Year by year, EBIT stood at -$47.6 million in 2022, then tumbled by 31.76% to -$62.7 million in 2023, then tumbled by 51.21% to -$94.7 million in 2024, then tumbled by 41.08% to -$133.7 million in 2025, then dropped by 5.02% to -$140.4 million in 2026.
  • Per Business Quant, the three latest CRNX EBIT figures stand at -$140.4 million (Q1 2026), -$133.7 million (Q4 2025), and -$142.6 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -27.75 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 249.90 Mn
4 NuCana 279.75 Bn 279.75 Bn - -3.72 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -32.68 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 493.00 Mn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -445.22 Mn
10 Crinetics Pharmaceuticals 8.71 Bn 8.71 Bn 10.53 Mn -140.38 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -140.38 Mn
Dec 31, 2025 -133.67 Mn
Sep 30, 2025 -142.59 Mn
Jun 30, 2025 -129.11 Mn
Mar 31, 2025 -111.41 Mn
Dec 31, 2024 -94.75 Mn
Sep 30, 2024 -87.80 Mn
Jun 30, 2024 -82.78 Mn
Mar 31, 2024 -73.53 Mn
Dec 31, 2023 -62.66 Mn
Sep 30, 2023 -58.98 Mn
Jun 30, 2023 -53.00 Mn
Mar 31, 2023 -47.98 Mn
Dec 31, 2022 -47.56 Mn
Sep 30, 2022 -43.45 Mn
Jun 30, 2022 -43.05 Mn
Mar 31, 2022 -33.83 Mn
Dec 31, 2021 -30.89 Mn
Sep 30, 2021 -27.81 Mn
Jun 30, 2021 -26.09 Mn