Crinetics Pharmaceuticals (CRNX) EBIT (2017 - 2026)

Crinetics Pharmaceuticals (CRNX) recorded quarterly EBIT of -$140.4 million in Q1 2026, down 5.02% quarter-over-quarter from -$133.7 million in Q4 2025, and down 26.01% on a YoY basis from -$189.7 million in Q1 2025.

Crinetics Pharmaceuticals (CRNX) EBIT (2017 - 2026) Analysis & Trends

Crinetics Pharmaceuticals' EBIT history runs 10 years deep, the most recent figure standing at -$140.4 million for Q1 2026.

  • In Q1 2026, EBIT fell 26.01% year-over-year to -$140.4 million; the TTM figure through Mar 2026 stood at -$545.7 million (down 44.86% YoY), while the FY2025 annual figure was -$516.8 million, down 52.5% from the prior year.
  • EBIT was -$140.4 million for Q1 2026 at Crinetics Pharmaceuticals, down from -$133.7 million in the prior quarter.
  • In the past five years, EBIT ranged from a high of -$33.8 million in Q1 2022 to a low of -$142.6 million in Q3 2025.
  • Historically, EBIT has averaged -$81.6 million across 5 years, with a median of -$73.5 million in 2024.
  • The sharpest annual moves came in 2022 and 2023: EBIT tumbled 64.99% in 2022, then slipped 23.12% in 2023.
  • A 5-year view of EBIT shows it stood at -$47.6 million in 2022, then sank by 31.76% to -$62.7 million in 2023, then sank by 51.21% to -$94.7 million in 2024, then sank by 41.08% to -$133.7 million in 2025, then dropped by 5.02% to -$140.4 million in 2026.
  • The last three EBIT figures came in at -$140.4 million (Q1 2026), -$133.7 million (Q4 2025), and -$142.6 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -32.68 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -15.76 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -1.51 Mn
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Crinetics Pharmaceuticals 3.75 Bn 3.75 Bn 10.53 Mn -140.38 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -140.38 Mn
Dec 31, 2025 -133.67 Mn
Sep 30, 2025 -142.59 Mn
Jun 30, 2025 -129.11 Mn
Mar 31, 2025 -111.41 Mn
Dec 31, 2024 -94.75 Mn
Sep 30, 2024 -87.80 Mn
Jun 30, 2024 -82.78 Mn
Mar 31, 2024 -73.53 Mn
Dec 31, 2023 -62.66 Mn
Sep 30, 2023 -58.98 Mn
Jun 30, 2023 -53.00 Mn
Mar 31, 2023 -47.98 Mn
Dec 31, 2022 -47.56 Mn
Sep 30, 2022 -43.45 Mn
Jun 30, 2022 -43.05 Mn
Mar 31, 2022 -33.83 Mn
Dec 31, 2021 -30.89 Mn
Sep 30, 2021 -27.81 Mn
Jun 30, 2021 -26.09 Mn