Curis (CRIS) Net Margin (2010 - 2025)
Curis (CRIS) reported Net Margin of 1700.88% for Q4 2025, up 198841.0% on a YoY basis from N/an in Q4 2024, and up 798.92% quarter-over-quarter from 243.36% in Q3 2025.
Curis (CRIS) Net Margin (2010 - 2025) Analysis & Trends
Curis has reported Net Margin for 16 years, with the latest figure at 1700.88% in Q4 2025.
- For the quarter ending Q4 2025, Net Margin rose 198841.0% year-over-year to 1700.88%; the trailing twelve-month figure through Mar 2026 stood at 119.04% (up 25704.0% YoY), and the FY2025 full-year result was 80.29%, up 31748.0% from the prior year.
- Net Margin for Q4 2025 stood at 1700.88%, up from 243.36% in the prior quarter.
- The five-year high for Net Margin was 1700.88% in Q4 2025, with the low at 783.13% in Q1 2022.
- Historically, Net Margin has averaged 347.74% across 5 years, with a median of 440.25% in 2021.
- Annual changes were most pronounced in 2022 — Net Margin plunged 32964 bps — and 2025, when it jumped 198841 bps.
- Curis' Net Margin stood at 434.45% in 2021, then climbed by 10 bps to 392.41% in 2022, then fell by 11 bps to 434.42% in 2023, then soared by 34 bps to 287.53% in 2024, then surged by 692 bps to 1700.88% in 2025.
- The last three Net Margin figures came in at 1700.88% (Q4 2025), 243.36% (Q3 2025), and 312.59% (Q2 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 788,338.31 Bn | 788,338.28 Bn | - | - |
| 2 | Belite Bio | 56,560.00 Bn | 56,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,329.30 Bn | 17,329.30 Bn | - | - |
| 4 | Legend Biotech | 3,341.00 Bn | 3,340.71 Bn | 242.10 Mn | 0.82% |
| 5 | Akari Therapeutics | 1,727.91 Bn | 1,727.91 Bn | - | - |
| 6 | Evaxion A | 1,536.68 Bn | 1,536.67 Bn | - | - |
| 7 | Psyence Biomedical | 238.34 Bn | 238.33 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 113.42 Bn | 106.17 Bn | 2.59 Bn | 34.53% |
| 9 | Abivax | 95.45 Bn | 95.45 Bn | - | - |
| 10 | Curis | 8.58 Mn | -6.42 Mn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 1,700.88% |
| Sep 30, 2025 | -243.36% |
| Jun 30, 2025 | -312.59% |
| Mar 31, 2025 | -446.05% |
| Dec 31, 2024 | -287.53% |
| Sep 30, 2024 | -344.32% |
| Jun 30, 2024 | -463.59% |
| Mar 31, 2024 | -569.32% |
| Dec 31, 2023 | -434.42% |
| Sep 30, 2023 | -429.97% |
| Jun 30, 2023 | -544.42% |
| Mar 31, 2023 | -503.22% |
| Dec 31, 2022 | -392.41% |
| Sep 30, 2022 | -470.58% |
| Jun 30, 2022 | -666.11% |
| Mar 31, 2022 | -783.13% |
| Dec 31, 2021 | -434.45% |
| Sep 30, 2021 | -363.64% |
| Jun 30, 2021 | -513.04% |
| Mar 31, 2021 | -453.49% |