Cardiff Oncology CRDF
NASDAQ CRDF
$0.88 -0.03 (-3.15%)
At close: Aug 21, 2026 · 4:00 PM EDT

Cardiff Oncology (CRDF) Return on Capital Employed (2012 - 2026)

Cardiff Oncology (CRDF) posted Return on Capital Employed of 105.43% for Q4 2025, down 8.08% sequentially from 97.55% in Q3 2025, and down 3240.0% YoY from 3.36% in Q4 2024.

Cardiff Oncology (CRDF) Return on Capital Employed (2012 - 2026) Analysis & Trends

Cardiff Oncology has reported Return on Capital Employed for 14 years, with the latest figure at 105.43% in Q4 2025.

  • Quarterly Return on Capital Employed fell 3240.0% year-over-year to 105.43% in Q4 2025, while the trailing twelve-month figure through Dec 2025 was 105.43% (down 3240.0% YoY) and the FY2025 annual result came in at 77.54%, down 1351.0% from the prior year.
  • Return on Capital Employed slipped to 105.43% in Q4 2025 per CRDF's latest filing, from 97.55% in the prior quarter.
  • Over five years, Return on Capital Employed peaked at 15.98% in Q1 2021 and troughed at 105.43% in Q4 2025.
  • A 5-year average of 52.96% and a median of 49.45% in 2023 frame the typical range for Return on Capital Employed.
  • The sharpest annual moves came in 2021 and 2024: Return on Capital Employed jumped 20649 bps in 2021, then slumped 3636 bps in 2024.
  • Over 5 years, Return on Capital Employed stood at 20.78% in 2021, then plunged by 71 bps to 35.59% in 2022, then slumped by 71 bps to 60.87% in 2023, then slipped by 20 bps to 73.03% in 2024, then slumped by 44 bps to 105.43% in 2025.
  • According to Business Quant data, Return on Capital Employed over the past three periods registered 105.43%, 97.55%, and 85.42% for Q4 2025, Q3 2025, and Q2 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Vertex Pharmaceuticals 139.13 Bn 131.28 Bn 2.84 Bn 20.76%
2 Regeneron Pharmaceuticals 85.77 Bn 77.77 Bn 3.93 Bn 10.74%
3 Argenx Se 64.64 Bn 59.46 Bn 1.37 Bn -
4 Moderna 58.29 Bn 53.16 Bn 52.00 Mn -38.20%
5 BeOne Medicines 41.92 Bn 36.82 Bn 1.53 Bn 13.68%
6 Alnylam Pharmaceuticals 31.58 Bn 28.28 Bn 992.69 Mn 26.09%
7 BioNTech SE 28.12 Bn 9.73 Bn 668.28 Mn -6.85%
8 Insmed 27.39 Bn 26.22 Bn 358.27 Mn -50.93%
9 Royalty Pharma 27.27 Bn 26.43 Bn - 7.88%
10 Cardiff Oncology 60.21 Mn 60.21 Mn - -113.87%

Historic Data

Download Data
DateValue
Jun 30, 2026 -113.87%
Dec 31, 2025 -105.43%
Sep 30, 2025 -97.55%
Jun 30, 2025 -85.42%
Mar 31, 2025 -67.05%
Dec 31, 2024 -73.03%
Sep 30, 2024 -89.34%
Jun 30, 2024 -77.59%
Mar 31, 2024 -67.12%
Dec 31, 2023 -60.87%
Sep 30, 2023 -52.98%
Jun 30, 2023 -45.91%
Mar 31, 2023 -39.60%
Dec 31, 2022 -35.59%
Sep 30, 2022 -33.59%
Jun 30, 2022 -30.01%
Mar 31, 2022 -25.04%
Dec 31, 2021 -20.78%
Sep 30, 2021 -18.79%
Jun 30, 2021 -17.56%