Caribou Biosciences (CRBU) Return on Equity [ROE] (2021 - 2026)
Caribou Biosciences (CRBU) reported Return on Equity [ROE] of -109.41% for Q2 2026, down 21.97 percentage points from -87.44% a year earlier but up 8.09 percentage points from the prior quarter.
Caribou Biosciences (CRBU) Return on Equity [ROE] (2021 - 2026) Analysis & Trends
For FY2025, Caribou Biosciences posted Return on Equity [ROE] of -78.97%, down 30.98 percentage points from FY2024.
- Return on Equity [ROE] has declined for three consecutive years, with a four-year change of -42.24 percentage points (FY2021 to FY2025).
- By year, Return on Equity [ROE] came in at -47.99% in FY2024 (-17.49 pp), -30.50% in FY2023 (-1.63 pp), -28.87% in FY2022 (+7.86 pp) and -36.73% in FY2021.
- Five-year quarterly Return on Equity [ROE] spans a low of -117.50% in Q1 2026 and a high of -16.89% in Q4 2021.
- Year over year, Return on Equity [ROE] has now declined in each of the last eight quarters, with an average year-over-year change of -37.41 percentage points over the last eight quarters.
- The high point for year-over-year Return on Equity [ROE] in five years was Q3 2022 (a gain of 7.34 percentage points); the low point was Q4 2025 (a drop of 49.99 percentage points).
- Per Business Quant data, the three quarters before Q2 2026 came in at -117.50% (Q1 2026), -112.37% (Q4 2025) and -103.10% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 25.32% |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | - |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | 7.21% |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 84.40% |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | 21.39% |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 83.75% |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | -18.38% |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | 4.97% |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 22.24% |
| 10 | Caribou Biosciences | 134.61 Mn | -381.92 Mn | - | -109.41% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -109.41% |
| Mar 31, 2026 | -117.50% |
| Dec 31, 2025 | -112.37% |
| Sep 30, 2025 | -103.10% |
| Jun 30, 2025 | -87.44% |
| Mar 31, 2025 | -69.56% |
| Dec 31, 2024 | -62.39% |
| Sep 30, 2024 | -55.84% |
| Jun 30, 2024 | -43.31% |
| Mar 31, 2024 | -36.80% |
| Dec 31, 2023 | -30.28% |
| Sep 30, 2023 | -32.71% |
| Jun 30, 2023 | -44.22% |
| Mar 31, 2023 | -40.29% |
| Dec 31, 2022 | -34.05% |
| Sep 30, 2022 | -28.07% |
| Jun 30, 2022 | -24.66% |
| Mar 31, 2022 | -19.65% |
| Dec 31, 2021 | -16.89% |
| Sep 30, 2021 | -35.41% |
Caribou Biosciences Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=CRBU&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "CRBU", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=CRBU&period=max&api_key=YOUR_API_KEY");
const data = await res.json();