Growth Metrics

Caribou Biosciences (CRBU) Net Cash Flow (2020 - 2026)

Caribou Biosciences (CRBU) reported Net Cash Flow of -$319000.0 for Q1 2026, down 102.43% year-over-year from $13.1 million in Q1 2025, and down 126.41% on a QoQ basis from $1.2 million in Q4 2025.

Caribou Biosciences (CRBU) has 7 years of Net Cash Flow data on file, last reported at -$319000.0 in Q1 2026.

  • Quarterly Net Cash Flow fell 102.43% year-over-year to -$319000.0 in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$17.4 million (up 13.01% YoY) and the FY2025 annual result came in at -$3.9 million, up 88.7% from the prior year.
  • Net Cash Flow fell to -$319000.0 in Q1 2026 per CRBU's latest filing, from $1.2 million in the prior quarter.
  • Across five years, Net Cash Flow topped out at $37.9 million in Q3 2023 and bottomed at -$92.8 million in Q1 2022.
  • The 5-year median for Net Cash Flow is -$5.9 million (2024), against an average of -$13.4 million.
  • The widest annual swing landed in 2024, when Net Cash Flow sank 185.75%; it then soared 844.84% in 2025.
  • Tracing CRBU's Net Cash Flow over 5 years: stood at -$23.7 million in 2022, then sank by 122.75% to -$52.9 million in 2023, then surged by 70.36% to -$15.7 million in 2024, then jumped by 107.71% to $1.2 million in 2025, then slumped by 126.41% to -$319000.0 in 2026.
  • Per Business Quant, the three latest CRBU Net Cash Flow figures stand at -$319000.0 (Q1 2026), $1.2 million (Q4 2025), and -$14.1 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Cash Flow (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 2.44 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 625.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -2.44 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 457.40 Mn
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn -152.20 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 60.68 Mn
10 Caribou Biosciences 232.46 Mn 114.84 Mn - -319,000.00

Historic Data

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DateValue
Mar 31, 2026 -319,000.00
Mar 31, 2026 -319,000.00
Dec 31, 2025 1.21 Mn
Dec 31, 2025 1.21 Mn
Sep 30, 2025 -14.06 Mn
Sep 30, 2025 -14.06 Mn
Jun 30, 2025 -4.22 Mn
Jun 30, 2025 -4.22 Mn
Mar 31, 2025 13.12 Mn
Mar 31, 2025 13.12 Mn
Dec 31, 2024 -15.68 Mn
Dec 31, 2024 -15.68 Mn
Sep 30, 2024 -5.90 Mn
Sep 30, 2024 -5.90 Mn
Jun 30, 2024 -11.53 Mn
Jun 30, 2024 -11.53 Mn
Mar 31, 2024 -1.76 Mn
Mar 31, 2024 -1.76 Mn
Dec 31, 2023 -52.90 Mn
Dec 31, 2023 -52.90 Mn
Sep 30, 2023 37.86 Mn
Sep 30, 2023 37.86 Mn
Jun 30, 2023 13.45 Mn
Jun 30, 2023 13.45 Mn
Mar 31, 2023 -5.59 Mn
Mar 31, 2023 -5.59 Mn
Dec 31, 2022 -23.75 Mn
Dec 31, 2022 -23.75 Mn
Sep 30, 2022 -30.06 Mn
Sep 30, 2022 -30.06 Mn
Jun 30, 2022 -35.48 Mn
Jun 30, 2022 -35.48 Mn
Mar 31, 2022 -92.79 Mn
Mar 31, 2022 -92.79 Mn
Dec 31, 2021 -194.89 Mn
Dec 31, 2021 -194.89 Mn
Sep 30, 2021 305.79 Mn
Sep 30, 2021 305.79 Mn
Jun 30, 2021 -16.35 Mn
Jun 30, 2021 -16.35 Mn
Mar 31, 2021 129.97 Mn
Mar 31, 2021 129.97 Mn
Dec 31, 2020 -8.59 Mn
Dec 31, 2020 -8.59 Mn
Sep 30, 2020 -8.58 Mn
Sep 30, 2020 -8.58 Mn