Growth Metrics

Caribou Biosciences (CRBU) Free Cash Flow (2020 - 2026)

Caribou Biosciences (CRBU) reported Free Cash Flow of -$27.0 million for Q1 2026, up 26.71% year-over-year from -$21.3 million in Q1 2025, and down 30.97% on a QoQ basis from -$20.6 million in Q4 2025.

Caribou Biosciences (CRBU) has 7 years of Free Cash Flow data on file, last reported at -$27.0 million in Q1 2026.

  • Quarterly Free Cash Flow rose 26.71% year-over-year to -$27.0 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$102.5 million (up 25.57% YoY) and the FY2025 annual result came in at -$112.4 million, up 19.14% from the prior year.
  • Free Cash Flow retreated to -$27.0 million in Q1 2026 per CRBU's latest filing, from -$20.6 million in the prior quarter.
  • Across five years, Free Cash Flow topped out at -$18.1 million in Q2 2023 and bottomed at -$38.1 million in Q1 2024.
  • The 5-year median for Free Cash Flow is -$26.4 million (2022), against an average of -$27.3 million.
  • The widest annual swing landed in 2022, when Free Cash Flow sank 211.65%; it then soared 42.5% in 2025.
  • Tracing CRBU's Free Cash Flow over 5 years: stood at -$21.6 million in 2022, then increased by 0.25% to -$21.5 million in 2023, then plunged by 66.63% to -$35.9 million in 2024, then soared by 42.5% to -$20.6 million in 2025, then plunged by 30.97% to -$27.0 million in 2026.
  • Per Business Quant, the three latest CRBU Free Cash Flow figures stand at -$27.0 million (Q1 2026), -$20.6 million (Q4 2025), and -$25.3 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -1.67 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -12.20 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -2.49 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.29 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 848.30 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 48.67 Mn
10 Caribou Biosciences 232.46 Mn 114.84 Mn - -27.00 Mn

Historic Data

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DateValue
Mar 31, 2026 -27.00 Mn
Mar 31, 2026 -27.00 Mn
Dec 31, 2025 -20.62 Mn
Dec 31, 2025 -20.62 Mn
Sep 30, 2025 -25.30 Mn
Sep 30, 2025 -25.30 Mn
Jun 30, 2025 -29.60 Mn
Jun 30, 2025 -29.60 Mn
Mar 31, 2025 -36.84 Mn
Mar 31, 2025 -36.84 Mn
Dec 31, 2024 -35.85 Mn
Dec 31, 2024 -35.85 Mn
Sep 30, 2024 -32.86 Mn
Sep 30, 2024 -32.86 Mn
Jun 30, 2024 -32.19 Mn
Jun 30, 2024 -32.19 Mn
Mar 31, 2024 -38.05 Mn
Mar 31, 2024 -38.05 Mn
Dec 31, 2023 -21.52 Mn
Dec 31, 2023 -21.52 Mn
Sep 30, 2023 -24.76 Mn
Sep 30, 2023 -24.76 Mn
Jun 30, 2023 -18.06 Mn
Jun 30, 2023 -18.06 Mn
Mar 31, 2023 -29.65 Mn
Mar 31, 2023 -29.65 Mn
Dec 31, 2022 -21.57 Mn
Dec 31, 2022 -21.57 Mn
Sep 30, 2022 -26.37 Mn
Sep 30, 2022 -26.37 Mn
Jun 30, 2022 -21.60 Mn
Jun 30, 2022 -21.60 Mn
Mar 31, 2022 -22.65 Mn
Mar 31, 2022 -22.65 Mn
Dec 31, 2021 -22.07 Mn
Dec 31, 2021 -22.07 Mn
Sep 30, 2021 -15.90 Mn
Sep 30, 2021 -15.90 Mn
Jun 30, 2021 -16.96 Mn
Jun 30, 2021 -16.96 Mn
Mar 31, 2021 20.29 Mn
Mar 31, 2021 20.29 Mn
Dec 31, 2020 -8.10 Mn
Dec 31, 2020 -8.10 Mn
Sep 30, 2020 -8.71 Mn
Sep 30, 2020 -8.71 Mn