Caribou Biosciences (CRBU) EBITDA Margin (2020 - 2026)
Caribou Biosciences (CRBU) recorded EBITDA Margin of -1648.70% in Q2 2026, up 91.50 percentage points from -1740.19% a year earlier but down 579.40 percentage points from the prior quarter.
Powered by 
Analysis
Caribou Biosciences (CRBU) EBITDA Margin (2020 - 2026) Analysis & Trends
On a TTM basis, Caribou Biosciences' EBITDA Margin came in at -1065.12% as of Jun 30, 2026, up 720.99 percentage points year-over-year; for FY2025, it came in at -1296.70%, up 331.16 percentage points from FY2024.
- Annual EBITDA Margin has a five-year change of -1011.74 percentage points (FY2020 to FY2025).
- Across earlier years, EBITDA Margin came in at -1627.87% in FY2024 (-1301.46 pp), -326.40% in FY2023 (+430.05 pp), -756.46% in FY2022 (-68.87 pp) and -687.59% in FY2021 (-402.63 pp).
- Quarterly EBITDA Margin has ranged from -1864.64% in Q1 2024 to -55.17% in Q3 2023 over the past five years.
- On a year-over-year basis, EBITDA Margin has increased for four consecutive quarters, with an average year-over-year change of -68.64 percentage points over the last eight quarters.
- Peak year-over-year performance for EBITDA Margin in the last five years was a gain of 1110.02 percentage points in Q4 2025, against a drop of 1775.91 percentage points in Q3 2024 at the low end.
- Per Business Quant, the preceding three quarters came in at -1069.29% (Q1 2026), -704.67% (Q4 2025) and -1308.87% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 35.95% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 49.01% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | 6.02% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | - |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 33.11% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 46.01% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -124.26% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 39.16% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 39.10% |
| 10 | Caribou Biosciences | 130.37 Mn | -386.16 Mn | - | -1,648.70% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -1,648.70% |
| Mar 31, 2026 | -1,069.29% |
| Dec 31, 2025 | -704.67% |
| Sep 30, 2025 | -1,308.87% |
| Jun 30, 2025 | -1,740.19% |
| Mar 31, 2025 | -1,774.25% |
| Dec 31, 2024 | -1,814.68% |
| Sep 30, 2024 | -1,831.08% |
| Jun 30, 2024 | -1,231.09% |
| Mar 31, 2024 | -1,864.64% |
| Dec 31, 2023 | -1,031.53% |
| Sep 30, 2023 | -55.17% |
| Jun 30, 2023 | -858.88% |
| Mar 31, 2023 | -871.70% |
| Dec 31, 2022 | -814.52% |
| Sep 30, 2022 | -789.80% |
| Jun 30, 2022 | -669.68% |
| Mar 31, 2022 | -771.21% |
| Dec 31, 2021 | -786.71% |
| Sep 30, 2021 | -461.55% |
API Access
Caribou Biosciences EBITDA Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda-margin&ticker=CRBU&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda-margin", "ticker": "CRBU", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebitda-margin&ticker=CRBU&period=max&api_key=YOUR_API_KEY");
const data = await res.json();