Cellectis (CLLS) Return on Capital Employed (2015 - 2026)

Cellectis' (CLLS) quarterly Return on Capital Employed came in at 25.55% in Q1 2026, down 54.0% year-on-year from 55.55% in Q1 2025, and down 45.33% quarter-over-quarter from 17.58% in Q4 2025.

Cellectis (CLLS) Return on Capital Employed (2015 - 2026) Analysis & Trends

Cellectis' Return on Capital Employed history runs 12 years deep, the most recent figure standing at 25.55% for Q1 2026.

  • On a quarterly basis, Return on Capital Employed fell 54.0% year-over-year to 25.55% in Q1 2026; TTM through Mar 2026 was 25.55%, a 54.0% decrease from a year earlier, with the FY2025 full-year figure at 28.58%, up 234.0% from the prior year.
  • Return on Capital Employed fell to 25.55% in Q1 2026 per CLLS's latest filing, from 17.58% in the prior quarter.
  • Across five years, Return on Capital Employed topped out at 13.21% in Q3 2025 and bottomed at 83.28% in Q4 2023.
  • The 5-year median for Return on Capital Employed is 39.95% (2024), against an average of 37.18%.
  • Across the five-year window, Return on Capital Employed plunged 4299 bps in 2023 and jumped 5662 bps in 2024, its largest moves.
  • Year by year, Return on Capital Employed stood at 40.29% in 2022, then tumbled by 107 bps to 83.28% in 2023, then soared by 68 bps to 26.65% in 2024, then surged by 34 bps to 17.58% in 2025, then slumped by 45 bps to 25.55% in 2026.
  • Per Business Quant, the three latest CLLS Return on Capital Employed figures stand at 25.55% (Q1 2026), 17.58% (Q4 2025), and 13.21% (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -31.80%
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 10.46%
4 NuCana 279.75 Bn 279.75 Bn - -68.47%
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 21.10%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 10.19%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -68.84%
10 Cellectis 281.48 Mn 95.81 Mn - -25.55%

Historic Data

Download Data
DateValue
Mar 31, 2026 -25.55%
Dec 31, 2025 -17.58%
Sep 30, 2025 -13.21%
Jun 30, 2025 -23.60%
Mar 31, 2025 -25.01%
Dec 31, 2024 -26.65%
Sep 30, 2024 -33.26%
Jun 30, 2024 -39.95%
Mar 31, 2024 -50.97%
Dec 31, 2023 -83.28%
Sep 30, 2023 -42.00%
Jun 30, 2023 -40.54%
Mar 31, 2023 -39.29%
Dec 31, 2022 -40.29%
Sep 30, 2022 -43.87%
Jun 30, 2022 -44.29%
Mar 31, 2022 -42.79%
Dec 31, 2021 -35.71%
Sep 30, 2021 -36.02%
Jun 30, 2021 -31.58%