Growth Metrics

Cellectis (CLLS) EBITDA Margin (2015 - 2026)

Cellectis (CLLS) posted EBITDA Margin of 435.64% for Q1 2026, down 219.25% on a QoQ basis from 136.46% in Q4 2025, and down 30257.0% year-over-year from N/an in Q1 2025.

Cellectis (CLLS) has 12 years of EBITDA Margin data on file, last reported at 435.64% in Q1 2026.

  • In Q1 2026, EBITDA Margin fell 30257.0% year-over-year to 435.64%; the TTM figure through Mar 2026 stood at 62.6% (up 3287.0% YoY), while the FY2025 annual figure was 81.64%, up 3937.0% from the prior year.
  • EBITDA Margin slipped to 435.64% in Q1 2026, from 136.46% in the prior quarter.
  • Across five years, EBITDA Margin topped out at 22.86% in Q3 2025 and bottomed at 16856.83% in Q1 2023.
  • A 5-year average of 4408.53% and a median of 435.64% in 2026 frame the typical range for EBITDA Margin.
  • Annual changes were most pronounced in 2022 — EBITDA Margin slumped 1512056 bps — and 2024, when it jumped 1639539 bps.
  • Year by year, EBITDA Margin stood at 21.09% in 2022, then plunged by 49450 bps to 10451.94% in 2023, then soared by 99 bps to 52.28% in 2024, then plunged by 161 bps to 136.46% in 2025, then slumped by 219 bps to 435.64% in 2026.
  • The last three EBITDA Margin figures came in at 435.64% (Q1 2026), 136.46% (Q4 2025), and 22.86% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA Margin (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -6.43%
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 38.10%
7 Evaxion A 64.16 Bn 64.14 Bn - -
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 18.35%
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 17.24%
10 Cellectis 20.83 Bn 20.62 Bn - -435.64%

Historic Data

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DateValue
Mar 31, 2026 -435.64%
Dec 31, 2025 -136.46%
Sep 30, 2025 22.86%
Jun 30, 2025 -57.32%
Mar 31, 2025 -133.07%
Dec 31, 2024 -52.28%
Sep 30, 2024 -66.48%
Jun 30, 2024 -213.51%
Mar 31, 2024 -461.44%
Dec 31, 2023 -10,451.94%
Sep 30, 2023 -13,336.13%
Jun 30, 2023 -13,270.22%
Mar 31, 2023 -16,856.83%
Dec 31, 2022 -21.09%
Sep 30, 2022 -15,630.29%
Jun 30, 2022 -2,089.75%
Mar 31, 2022 -1,755.44%
Dec 31, 2021 -74.80%
Sep 30, 2021 -509.72%
Jun 30, 2021 -335.37%
Mar 31, 2021 -77.76%
Dec 31, 2020 -286.94%
Sep 30, 2020 -475.04%
Jun 30, 2020 -1,139.00%
Mar 31, 2020 28.75%
Dec 31, 2019 -870.34%
Sep 30, 2019 -314.02%
Jun 30, 2019 -3,049.13%
Mar 31, 2019 -2,231.56%
Dec 31, 2018 -3,023.24%
Sep 30, 2018 -3,190.29%
Jun 30, 2018 -429.71%
Mar 31, 2018 -412.28%
Dec 31, 2017 -401.77%
Sep 30, 2017 -419.85%
Jun 30, 2017 -305.45%
Mar 31, 2017 -293.25%
Dec 31, 2016 -247.87%
Sep 30, 2016 -114.48%
Jun 30, 2016 -1,678.06%
Mar 31, 2016 -292.48%
Dec 31, 2015 3.65%
Sep 30, 2015 -176.93%
Jun 30, 2015 -165.47%
Mar 31, 2015 -42.22%