C4 Therapeutics (CCCC) Return on Capital Employed [ROCE] (2020 - 2026)
C4 Therapeutics' Return on Capital Employed [ROCE] was -37.77% in Q2 2026, up 9.13 percentage points from -46.90% a year earlier but down 1.83 percentage points from the prior quarter.
Powered by 
Analysis
C4 Therapeutics (CCCC) Return on Capital Employed [ROCE] (2020 - 2026) Analysis & Trends
For FY2025, Return on Capital Employed [ROCE] at C4 Therapeutics came in at -35.86%, up 1.77 percentage points from FY2024.
- Return on Capital Employed [ROCE] shows a five-year change of -7.79 percentage points (FY2020 to FY2025).
- In earlier years, Return on Capital Employed [ROCE] was -37.63% in FY2024 (+0.89 pp), -38.53% in FY2023 (-7.99 pp), -30.53% in FY2022 (-10.11 pp) and -20.42% in FY2021 (+7.65 pp).
- Quarterly Return on Capital Employed [ROCE] has moved between -52.96% (Q3 2025) and -18.01% (Q4 2021) over five years.
- Compared with a year earlier, Return on Capital Employed [ROCE] was higher in five of the last eight quarters, with an average year-over-year change of -0.51 percentage points.
- The best year-over-year quarter for Return on Capital Employed [ROCE] over five years was Q2 2026 (a gain of 9.13 percentage points); the worst was Q2 2023 (a drop of 21.40 percentage points).
- Per Business Quant data, CCCC's Return on Capital Employed [ROCE] in the three quarters before Q2 2026 was -35.94% (Q1 2026), -41.26% (Q4 2025) and -52.96% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROCE (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,082.65 Bn | 1,051.23 Bn | 19.71 Bn | 46.74% |
| 2 | Johnson & Johnson | 623.68 Bn | 542.21 Bn | 17.26 Bn | 17.83% |
| 3 | AbbVie | 459.43 Bn | 432.59 Bn | 12.70 Bn | 17.92% |
| 4 | Merck | 354.80 Bn | 309.23 Bn | 12.21 Bn | 6.28% |
| 5 | Novartis Ag | 269.16 Bn | 225.03 Bn | 11.24 Bn | 19.32% |
| 6 | Astrazeneca | 244.40 Bn | 217.97 Bn | 12.86 Bn | 9.54% |
| 7 | Amgen | 220.17 Bn | 175.57 Bn | 7.24 Bn | 16.66% |
| 8 | Gilead Sciences | 183.05 Bn | 157.16 Bn | 6.22 Bn | -5.97% |
| 9 | Pfizer | 160.27 Bn | 107.22 Bn | 10.94 Bn | 11.86% |
| 10 | C4 Therapeutics | 385.92 Mn | -543.83 Mn | - | -37.77% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -37.77% |
| Mar 31, 2026 | -35.94% |
| Dec 31, 2025 | -41.26% |
| Sep 30, 2025 | -52.96% |
| Jun 30, 2025 | -46.90% |
| Mar 31, 2025 | -39.68% |
| Dec 31, 2024 | -37.66% |
| Sep 30, 2024 | -35.59% |
| Jun 30, 2024 | -35.44% |
| Mar 31, 2024 | -40.62% |
| Dec 31, 2023 | -44.57% |
| Sep 30, 2023 | -43.21% |
| Jun 30, 2023 | -42.87% |
| Mar 31, 2023 | -35.93% |
| Dec 31, 2022 | -32.26% |
| Sep 30, 2022 | -24.67% |
| Jun 30, 2022 | -21.46% |
| Mar 31, 2022 | -20.04% |
| Dec 31, 2021 | -18.01% |
| Sep 30, 2021 | -18.27% |
API Access
C4 Therapeutics Return on Capital Employed [ROCE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-capital-employed-%5Broce%5D&ticker=CCCC&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-capital-employed-[roce]", "ticker": "CCCC", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-capital-employed-%5Broce%5D&ticker=CCCC&period=max&api_key=YOUR_API_KEY");
const data = await res.json();