CalciMedica (CALC) EBITDA Margin (2024 - 2026)
CalciMedica's (CALC) quarterly EBITDA Margin came in at 2634.27% in Q1 2026, down 1756.0% YoY from 159.07% in Q1 2025, and up 4.53% on a QoQ basis from 2520.11% in Q4 2025.
CalciMedica (CALC) EBITDA Margin (2024 - 2026) Analysis & Trends
CalciMedica (CALC) has 3 years of EBITDA Margin data on file, last reported at 2634.27% in Q1 2026.
- Quarterly EBITDA Margin fell 1756.0% year-over-year to 2634.27% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 645.05% (down 106042.0% YoY) and the FY2025 annual result came in at 25.15%, down 253.0% from the prior year.
- EBITDA Margin improved to 2634.27% in Q1 2026, from 2520.11% in the prior quarter.
- In the past five years, EBITDA Margin ranged from a high of 6366.35% in Q2 2025 to a low of 2884.11% in Q4 2024.
- A 3-year average of 1664.67% and a median of 1769.38% in 2024 frame the typical range for EBITDA Margin.
- The widest YoY moves for EBITDA Margin: up 540423 bps in 2025, down 35006 bps in 2025.
- Tracing CALC's EBITDA Margin over 3 years: stood at 2884.11% in 2024, then surged by 187 bps to 2520.11% in 2025, then advanced by 5 bps to 2634.27% in 2026.
- The last three EBITDA Margin figures came in at 2634.27% (Q1 2026), 2520.11% (Q4 2025), and 190.05% (Q3 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 139.13 Bn | 131.28 Bn | 2.84 Bn | 37.40% |
| 2 | Regeneron Pharmaceuticals | 85.77 Bn | 77.77 Bn | 3.93 Bn | 30.15% |
| 3 | Argenx Se | 64.64 Bn | 59.46 Bn | 1.37 Bn | 32.54% |
| 4 | Moderna | 58.29 Bn | 53.16 Bn | 52.00 Mn | -562.07% |
| 5 | BeOne Medicines | 41.92 Bn | 36.82 Bn | 1.53 Bn | 19.06% |
| 6 | Alnylam Pharmaceuticals | 31.58 Bn | 28.28 Bn | 992.69 Mn | 17.93% |
| 7 | BioNTech SE | 28.12 Bn | 9.73 Bn | 668.28 Mn | -35.57% |
| 8 | Insmed | 27.39 Bn | 26.22 Bn | 358.27 Mn | -0.36% |
| 9 | Royalty Pharma | 27.27 Bn | 26.43 Bn | - | 19.75% |
| 10 | CalciMedica | 9.80 Mn | -8.82 Mn | - | 1,480.44% |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | 1,480.44% |
| Mar 31, 2026 | 2,634.27% |
| Dec 31, 2025 | 2,520.11% |
| Sep 30, 2025 | 190.05% |
| Jun 30, 2025 | 6,366.35% |
| Mar 31, 2025 | 2,651.84% |
| Dec 31, 2024 | -2,884.11% |
| Sep 30, 2024 | 540.11% |
| Jun 30, 2024 | 1,769.38% |
| Mar 31, 2024 | 1,194.00% |