Candel Therapeutics (CADL) Return on Capital Employed (2021 - 2025)

Candel Therapeutics (CADL) reported Return on Capital Employed of 48.07% for Q4 2025, up 7709.0% on a YoY basis from 0.62% in Q4 2024, and down 5.07% sequentially from 45.75% in Q3 2025.

Candel Therapeutics (CADL) Return on Capital Employed (2021 - 2025) Analysis & Trends

Candel Therapeutics (CADL) has 5 years of Return on Capital Employed data on file, last reported at 48.07% in Q4 2025.

  • For the quarter ending Q4 2025, Return on Capital Employed rose 7709.0% year-over-year to 48.07%; the trailing twelve-month figure through Dec 2025 stood at 48.07% (up 7709.0% YoY), and the FY2025 full-year result was 45.09%, up 4632.0% from the prior year.
  • Return on Capital Employed slipped to 48.07% in Q4 2025, from 45.75% in the prior quarter.
  • In the past five years, Return on Capital Employed ranged from a high of 29.5% in Q4 2021 to a low of 407.05% in Q3 2024.
  • A 5-year average of 92.3% and a median of 46.96% in 2025 frame the typical range for Return on Capital Employed.
  • Across the five-year window, Return on Capital Employed sank 32495 bps in 2024 and soared 36130 bps in 2025, its largest moves.
  • Tracing CADL's Return on Capital Employed over 5 years: stood at 29.5% in 2021, then slumped by 55 bps to 45.85% in 2022, then plunged by 166 bps to 122.08% in 2023, then fell by 3 bps to 125.16% in 2024, then jumped by 62 bps to 48.07% in 2025.
  • Business Quant data shows CADL's Return on Capital Employed at 48.07% in Q4 2025, 45.75% in Q3 2025, and 41.99% in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -31.80%
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 10.46%
4 NuCana 279.75 Bn 279.75 Bn - -68.47%
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 21.10%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 10.19%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -68.84%
10 Candel Therapeutics 542.51 Mn 542.51 Mn - -48.07%

Historic Data

Download Data
DateValue
Dec 31, 2025 -48.07%
Sep 30, 2025 -45.75%
Jun 30, 2025 -41.99%
Mar 31, 2025 -41.32%
Dec 31, 2024 -125.16%
Sep 30, 2024 -407.05%
Jun 30, 2024 -240.00%
Mar 31, 2024 -161.70%
Dec 31, 2023 -122.08%
Sep 30, 2023 -82.11%
Jun 30, 2023 -66.04%
Mar 31, 2023 -52.61%
Dec 31, 2022 -45.85%
Sep 30, 2022 -41.27%
Jun 30, 2022 -36.60%
Mar 31, 2022 -33.43%
Dec 31, 2021 -29.50%
Sep 30, 2021 -40.90%