Cabaletta Bio (CABA) Return on Capital Employed (2019 - 2025)

Cabaletta Bio's (CABA) quarterly Return on Capital Employed came in at 135.34% in Q4 2025, down 6069.0% year-on-year from 2.27% in Q4 2024, and down 33.66% quarter-over-quarter from 101.25% in Q3 2025.

Cabaletta Bio (CABA) Return on Capital Employed (2019 - 2025) Analysis & Trends

Cabaletta Bio's Return on Capital Employed history runs 7 years deep, the most recent figure standing at 135.34% for Q4 2025.

  • On a quarterly basis, Return on Capital Employed fell 6069.0% year-over-year to 135.34% in Q4 2025; TTM through Dec 2025 was 135.34%, a 6069.0% decrease from a year earlier, with the FY2025 full-year figure at 137.89%, down 7280.0% from the prior year.
  • Return on Capital Employed declined to 135.34% in Q4 2025 per CABA's latest filing, from 101.25% in the prior quarter.
  • Across five years, Return on Capital Employed topped out at 33.31% in Q1 2021 and bottomed at 135.34% in Q4 2025.
  • The 5-year median for Return on Capital Employed is 49.14% (2024), against an average of 59.44%.
  • Across the five-year window, Return on Capital Employed soared 2015 bps in 2024 and sank 6069 bps in 2025, its largest moves.
  • Year by year, Return on Capital Employed stood at 39.89% in 2021, then plunged by 43 bps to 57.09% in 2022, then surged by 34 bps to 37.81% in 2023, then slumped by 97 bps to 74.65% in 2024, then sank by 81 bps to 135.34% in 2025.
  • Per Business Quant, the three latest CABA Return on Capital Employed figures stand at 135.34% (Q4 2025), 101.25% (Q3 2025), and 97.78% (Q2 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -31.80%
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 10.46%
4 NuCana 279.75 Bn 279.75 Bn - -68.47%
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 21.10%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 10.19%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -68.84%
10 Cabaletta Bio 182.04 Mn 182.04 Mn - -135.34%

Historic Data

Download Data
DateValue
Dec 31, 2025 -135.34%
Sep 30, 2025 -101.25%
Jun 30, 2025 -97.78%
Mar 31, 2025 -95.14%
Dec 31, 2024 -74.65%
Sep 30, 2024 -60.89%
Jun 30, 2024 -47.44%
Mar 31, 2024 -37.43%
Dec 31, 2023 -37.81%
Sep 30, 2023 -40.28%
Jun 30, 2023 -44.94%
Mar 31, 2023 -57.58%
Dec 31, 2022 -57.09%
Sep 30, 2022 -56.82%
Jun 30, 2022 -50.83%
Mar 31, 2022 -43.87%
Dec 31, 2021 -39.89%
Sep 30, 2021 -38.39%
Jun 30, 2021 -38.03%
Mar 31, 2021 -33.31%