Growth Metrics

Cabaletta Bio (CABA) Return on Capital Employed (2019 - 2025)

Cabaletta Bio's quarterly Return on Capital Employed came in at 135.34% in Q4 2025, down 6069.0% year-on-year from 2.27% in Q4 2024, and down 33.66% quarter-over-quarter from 101.25% in Q3 2025.

Cabaletta Bio has reported Return on Capital Employed for 7 years, with the latest figure at 135.34% in Q4 2025.

  • For the quarter ending Q4 2025, Return on Capital Employed fell 6069.0% year-over-year to 135.34%; the trailing twelve-month figure through Dec 2025 stood at 135.34% (down 6069.0% YoY), and the FY2025 full-year result was 137.89%, down 7280.0% from the prior year.
  • Return on Capital Employed for Q4 2025 stood at 135.34%, down from 101.25% in the prior quarter.
  • The five-year high for Return on Capital Employed was 33.31% in Q1 2021, with the low at 135.34% in Q4 2025.
  • Average Return on Capital Employed over 5 years is 59.44%, with a median of 49.14% recorded in 2024.
  • Year-over-year, Return on Capital Employed soared 2015 bps in 2024 and sank 6069 bps in 2025.
  • Tracing CABA's Return on Capital Employed over 5 years: stood at 39.89% in 2021, then sank by 43 bps to 57.09% in 2022, then soared by 34 bps to 37.81% in 2023, then tumbled by 97 bps to 74.65% in 2024, then slumped by 81 bps to 135.34% in 2025.
  • The last three Return on Capital Employed figures came in at 135.34% (Q4 2025), 101.25% (Q3 2025), and 97.78% (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 450.31%
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 51.73%
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -107.40%
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 21.10%
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 10.19%
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 20.34%
10 Cabaletta Bio 194.84 Mn 61.24 Mn - -135.34%

Historic Data

Download Data 🔒
DateValue
Dec 31, 2025 -135.34%
Sep 30, 2025 -101.25%
Jun 30, 2025 -97.78%
Mar 31, 2025 -95.14%
Dec 31, 2024 -74.65%
Sep 30, 2024 -60.89%
Jun 30, 2024 -47.44%
Mar 31, 2024 -37.43%
Dec 31, 2023 -37.81%
Sep 30, 2023 -40.28%
Jun 30, 2023 -44.94%
Mar 31, 2023 -57.58%
Dec 31, 2022 -57.09%
Sep 30, 2022 -56.82%
Jun 30, 2022 -50.83%
Mar 31, 2022 -43.87%
Dec 31, 2021 -39.89%
Sep 30, 2021 -38.39%
Jun 30, 2021 -38.03%
Mar 31, 2021 -33.31%
Dec 31, 2020 -29.92%
Sep 30, 2020 -25.18%
Jun 30, 2020 -21.05%
Mar 31, 2020 -16.74%
Dec 31, 2019 -17.78%