Cabaletta Bio (CABA) Return on Capital Employed (2019 - 2025)

Cabaletta Bio (CABA) recorded quarterly Return on Capital Employed of 135.34% in Q4 2025, down 33.66% quarter-over-quarter from 101.25% in Q3 2025, and down 6069.0% on a YoY basis from 2.27% in Q4 2024.

Cabaletta Bio (CABA) Return on Capital Employed (2019 - 2025) Analysis & Trends

Cabaletta Bio's Return on Capital Employed history runs 7 years deep, the most recent figure standing at 135.34% for Q4 2025.

  • In Q4 2025, Return on Capital Employed fell 6069.0% year-over-year to 135.34%; the TTM figure through Dec 2025 stood at 135.34% (down 6069.0% YoY), while the FY2025 annual figure was 137.89%, down 7280.0% from the prior year.
  • Return on Capital Employed was 135.34% for Q4 2025 at Cabaletta Bio, down from 101.25% in the prior quarter.
  • In the past five years, Return on Capital Employed ranged from a high of 33.31% in Q1 2021 to a low of 135.34% in Q4 2025.
  • Historically, Return on Capital Employed has averaged 59.44% across 5 years, with a median of 49.14% in 2024.
  • The sharpest annual moves came in 2024 and 2025: Return on Capital Employed jumped 2015 bps in 2024, then sank 6069 bps in 2025.
  • A 5-year view of Return on Capital Employed shows it stood at 39.89% in 2021, then slumped by 43 bps to 57.09% in 2022, then surged by 34 bps to 37.81% in 2023, then plunged by 97 bps to 74.65% in 2024, then tumbled by 81 bps to 135.34% in 2025.
  • The last three Return on Capital Employed figures came in at 135.34% (Q4 2025), 101.25% (Q3 2025), and 97.78% (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 450.31%
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 51.73%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -107.40%
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 21.10%
9 Abivax 91.96 Bn 91.96 Bn - -50.43%
10 Cabaletta Bio 151.84 Mn 18.24 Mn - -135.34%

Historic Data

Download Data
DateValue
Dec 31, 2025 -135.34%
Sep 30, 2025 -101.25%
Jun 30, 2025 -97.78%
Mar 31, 2025 -95.14%
Dec 31, 2024 -74.65%
Sep 30, 2024 -60.89%
Jun 30, 2024 -47.44%
Mar 31, 2024 -37.43%
Dec 31, 2023 -37.81%
Sep 30, 2023 -40.28%
Jun 30, 2023 -44.94%
Mar 31, 2023 -57.58%
Dec 31, 2022 -57.09%
Sep 30, 2022 -56.82%
Jun 30, 2022 -50.83%
Mar 31, 2022 -43.87%
Dec 31, 2021 -39.89%
Sep 30, 2021 -38.39%
Jun 30, 2021 -38.03%
Mar 31, 2021 -33.31%