Cabaletta Bio (CABA) Return on Capital Employed (2019 - 2026)

Cabaletta Bio (CABA) posted quarterly Return on Capital Employed of 135.34% for Q4 2025, down 6069.0% year-over-year from 2.27% in Q4 2024, and down 33.66% quarter-over-quarter from 101.25% in Q3 2025.

Cabaletta Bio (CABA) Return on Capital Employed (2019 - 2026) Analysis & Trends

Cabaletta Bio's Return on Capital Employed history runs 7 years deep, the most recent figure standing at 135.34% for Q4 2025.

  • In Q4 2025, Return on Capital Employed fell 6069.0% year-over-year to 135.34%; the TTM figure through Dec 2025 stood at 135.34% (down 6069.0% YoY), while the FY2025 annual figure was 137.89%, down 7280.0% from the prior year.
  • Return on Capital Employed for Q4 2025 stood at 135.34%, down from 101.25% in the prior quarter.
  • The five-year high for Return on Capital Employed was 33.31% in Q1 2021, with the low at 135.34% in Q4 2025.
  • The 5-year median for Return on Capital Employed is 49.14% (2024), against an average of 59.44%.
  • The sharpest annual moves came in 2024 and 2025: Return on Capital Employed soared 2015 bps in 2024, then plunged 6069 bps in 2025.
  • Cabaletta Bio's Return on Capital Employed stood at 39.89% in 2021, then sank by 43 bps to 57.09% in 2022, then jumped by 34 bps to 37.81% in 2023, then tumbled by 97 bps to 74.65% in 2024, then slumped by 81 bps to 135.34% in 2025.
  • Business Quant data shows CABA's Return on Capital Employed at 135.34% in Q4 2025, 101.25% in Q3 2025, and 97.78% in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 20.76%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 10.74%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -
4 Revolution Medicines 43.64 Bn 43.64 Bn - -55.45%
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 13.68%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -0.20%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 7.88%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 26.09%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -50.93%
10 Cabaletta Bio 466.25 Mn 466.25 Mn - -109.43%

Historic Data

Download Data
DateValue
Jun 30, 2026 -109.43%
Dec 31, 2025 -135.34%
Sep 30, 2025 -101.25%
Jun 30, 2025 -97.78%
Mar 31, 2025 -95.14%
Dec 31, 2024 -74.65%
Sep 30, 2024 -60.89%
Jun 30, 2024 -47.44%
Mar 31, 2024 -37.43%
Dec 31, 2023 -37.81%
Sep 30, 2023 -40.28%
Jun 30, 2023 -44.94%
Mar 31, 2023 -57.58%
Dec 31, 2022 -57.09%
Sep 30, 2022 -56.82%
Jun 30, 2022 -50.83%
Mar 31, 2022 -43.87%
Dec 31, 2021 -39.89%
Sep 30, 2021 -38.39%
Jun 30, 2021 -38.03%