Cabaletta Bio, Inc. (CABA) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

101,968,182Shares Outstanding

19,364,145Shares held by institutions

$57,317,869Value of institutional holdings

66.25%Institutional ownership %

5.05%Shares Changed QoQ

89No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

The institutional landscape for Cabaletta Bio, Inc. (NASDAQ:CABA) includes 89 filers as of the latest reporting cycle ending December 2025.

Cabaletta Bio saw its institutional ownership percentage fell to 66.2% in December 2025 from 70.5% in September 2025.
Quarterly data indicates a 5.05% shift in institutional share volume, and the annual owner count reflects a decrease of 17.59%.
The latest 13F cycle for Cabaletta Bio reveals that of 89 total investors, 58 funds grew their exposure, whereas 18 reduced theirs and 13 made no changes.
This class of investors increased its holdings in Cabaletta Bio to 67.55Mn shares for the 13F-cycle ending December 2025, up by 3.25Mn shares quarter on quarter, and up 29.15Mn shares year over year.
With 9.68Mn shares, Bain Capital Life Sciences Investors, LLC commands the largest institutional position in Cabaletta Bio as of December 31, 2025, equating to 9.49% of the company.
Among the most significant buyers of Cabaletta Bio during December 2025 were MILLENNIUM MANAGEMENT LLC (2.05Mn), TWO SIGMA INVESTMENTS, LP (1.37Mn), SCHRODER INVESTMENT MANAGEMENT GROUP (756.64K), SUPERSTRING CAPITAL MANAGEMENT LP (709.02K), BlackRock, Inc. (707.60K).
Leading sellers of Cabaletta Bio stock in December 2025 included T. Rowe Price Investment Management, Inc. (4.36Mn), Woodline Partners LP (885.11K), CITADEL ADVISORS LLC (671.96K), Cormorant Asset Management, LP (600.00K), JPMORGAN CHASE & CO (527.84K).
The top 10 institutional holders of Cabaletta Bio for the quarter ending December 2025 included Bain Capital Life Sciences Investors, LLC (9.68Mn), JENNISON ASSOCIATES LLC (8.91Mn), ADAGE CAPITAL PARTNERS GP, L.L.C. (8.83Mn), VANGUARD GROUP INC (4.42Mn), Cormorant Asset Management, LP (4.40Mn), T. Rowe Price Investment Management, Inc. (4.00Mn), MILLENNIUM MANAGEMENT LLC (2.74Mn), BlackRock, Inc. (2.33Mn), SUPERSTRING CAPITAL MANAGEMENT LP (2.25Mn), TWO SIGMA INVESTMENTS, LP (1.84Mn).

89 Institutional Holders

19,364,145 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
Bain Capital Life Sciences Investors, LLC	31 Dec, 2025	9,677,125	0	0.00%	$21,192,904.00
JENNISON ASSOCIATES LLC	31 Dec, 2025	8,905,699	408,162	4.80%	$19,503,481.00
ADAGE CAPITAL PARTNERS GP, L.L.C.	31 Dec, 2025	8,829,758	0	0.00%	$19,337,170.00
VANGUARD GROUP INC	31 Dec, 2025	4,419,458	228,699	5.46%	$9,678,613.00
Cormorant Asset Management, LP	31 Dec, 2025	4,400,000	-600,000	-12.00%	$9,636,000.00
T. Rowe Price Investment Management, Inc.	31 Dec, 2025	4,004,046	-4,358,443	-52.12%	$8,769.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	2,736,912	2,050,099	298.49%	$5,993,837.00
BlackRock, Inc.	31 Dec, 2025	2,328,470	707,598	43.66%	$5,099,349.00
SUPERSTRING CAPITAL MANAGEMENT LP	31 Dec, 2025	2,253,550	709,025	45.91%	$4,935,275.00
TWO SIGMA INVESTMENTS, LP	31 Dec, 2025	1,839,799	1,369,324	291.05%	$4,029,160.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	1,522,583	183,160	13.67%	$3,334,457.00
MORGAN STANLEY	31 Dec, 2025	1,343,708	-130,968	-8.88%	$2,942,720.00
Woodline Partners LP	31 Dec, 2025	1,250,242	-885,106	-41.45%	$2,738,030.00
Schonfeld Strategic Advisors LLC	31 Dec, 2025	1,204,070	159,901	15.31%	$2,636,910.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	1,085,816	165,476	17.98%	$2,378,961.00
MARSHALL WACE, LLP	31 Dec, 2025	959,076	-366,967	-27.67%	$2,100,376.00
Opaleye Management Inc.	31 Dec, 2025	900,000	91,118	11.26%	$1,971,000.00
JANE STREET GROUP, LLC	31 Dec, 2025	841,249	546,387	185.30%	$1,842,336.00
SCHRODER INVESTMENT MANAGEMENT GROUP	31 Dec, 2025	756,637	756,637	0.00%	$1,626,770.00
TWO SIGMA ADVISERS, LP	31 Dec, 2025	737,900	406,900	122.93%	$1,616,001.00

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