BioNTech SE (BNTX) Research & Development (2018 - 2025)

BioNTech SE (BNTX) reported Research & Development of -$588.3 million for Q4 2025, up 10.01% on a YoY basis from -$534.8 million in Q4 2024, and up 10.9% sequentially from -$660.3 million in Q3 2025.

BioNTech SE (BNTX) Research & Development (2018 - 2025) Analysis & Trends

BioNTech SE (BNTX) has 8 years of Research & Development data on file, last reported at -$588.3 million in Q4 2025.

  • For the quarter ending Q4 2025, Research & Development rose 10.01% year-over-year to -$588.3 million; the trailing twelve-month figure through Dec 2025 stood at -$2.4 billion (up 2.51% YoY), and the FY2025 full-year result was -$2.4 billion, up 1.27% from the prior year.
  • Research & Development improved to -$588.3 million in Q4 2025, from -$660.3 million in the prior quarter.
  • In the past five years, Research & Development ranged from a high of -$242.2 million in Q2 2021 to a low of -$660.3 million in Q3 2025.
  • A 5-year average of -$473.9 million and a median of -$531.1 million in 2022 frame the typical range for Research & Development.
  • Across the five-year window, Research & Development tumbled 101360660.56% in 2021 and advanced 10.01% in 2025, its largest moves.
  • Tracing BNTX's Research & Development over 5 years: stood at -$310.6 million in 2021, then sank by 67.46% to -$520.1 million in 2022, then slipped by 19.53% to -$621.7 million in 2023, then declined by 5.16% to -$653.8 million in 2024, then gained by 10.01% to -$588.3 million in 2025.
  • Business Quant data shows BNTX's Research & Development at -$588.3 million in Q4 2025, -$660.3 million in Q3 2025, and -$576.3 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) R&D (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -17.94 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - 1.46 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 541.22 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 961.60 Mn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 1.54 Bn
7 Belite Bio 61.40 Bn 61.40 Bn - 15.66 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -443.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - 343.97 Mn
10 BioNTech SE 21.56 Bn 21.56 Bn 668.28 Mn -588.31 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -588.31 Mn
Sep 30, 2025 -660.28 Mn
Jun 30, 2025 -576.28 Mn
Mar 31, 2025 -552.87 Mn
Dec 31, 2024 -653.77 Mn
Sep 30, 2024 -604.35 Mn
Jun 30, 2024 -629.55 Mn
Mar 31, 2024 -551.33 Mn
Dec 31, 2023 -621.68 Mn
Sep 30, 2023 -542.01 Mn
Jun 30, 2023 -406.60 Mn
Mar 31, 2023 -358.50 Mn
Dec 31, 2022 -520.12 Mn
Sep 30, 2022 -344.63 Mn
Jun 30, 2022 -426.40 Mn
Mar 31, 2022 -320.76 Mn
Dec 31, 2021 -310.59 Mn
Sep 30, 2021 -307.09 Mn
Jun 30, 2021 -242.18 Mn
Mar 31, 2021 -260.79 Mn