BioNTech SE (BNTX) Research & Development (2018 - 2025)
BioNTech SE (BNTX) reported Research & Development of -$588.3 million for Q4 2025, up 10.01% on a YoY basis from -$534.8 million in Q4 2024, and up 10.9% sequentially from -$660.3 million in Q3 2025.
BioNTech SE (BNTX) Research & Development (2018 - 2025) Analysis & Trends
BioNTech SE (BNTX) has 8 years of Research & Development data on file, last reported at -$588.3 million in Q4 2025.
- For the quarter ending Q4 2025, Research & Development rose 10.01% year-over-year to -$588.3 million; the trailing twelve-month figure through Dec 2025 stood at -$2.4 billion (up 2.51% YoY), and the FY2025 full-year result was -$2.4 billion, up 1.27% from the prior year.
- Research & Development improved to -$588.3 million in Q4 2025, from -$660.3 million in the prior quarter.
- In the past five years, Research & Development ranged from a high of -$242.2 million in Q2 2021 to a low of -$660.3 million in Q3 2025.
- A 5-year average of -$473.9 million and a median of -$531.1 million in 2022 frame the typical range for Research & Development.
- Across the five-year window, Research & Development tumbled 101360660.56% in 2021 and advanced 10.01% in 2025, its largest moves.
- Tracing BNTX's Research & Development over 5 years: stood at -$310.6 million in 2021, then sank by 67.46% to -$520.1 million in 2022, then slipped by 19.53% to -$621.7 million in 2023, then declined by 5.16% to -$653.8 million in 2024, then gained by 10.01% to -$588.3 million in 2025.
- Business Quant data shows BNTX's Research & Development at -$588.3 million in Q4 2025, -$660.3 million in Q3 2025, and -$576.3 million in Q2 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | R&D (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -17.94 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | 1.46 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 541.22 Mn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 961.60 Mn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 1.54 Bn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | 15.66 Mn |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | -443.00 Mn |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | 343.97 Mn |
| 10 | BioNTech SE | 21.56 Bn | 21.56 Bn | 668.28 Mn | -588.31 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -588.31 Mn |
| Sep 30, 2025 | -660.28 Mn |
| Jun 30, 2025 | -576.28 Mn |
| Mar 31, 2025 | -552.87 Mn |
| Dec 31, 2024 | -653.77 Mn |
| Sep 30, 2024 | -604.35 Mn |
| Jun 30, 2024 | -629.55 Mn |
| Mar 31, 2024 | -551.33 Mn |
| Dec 31, 2023 | -621.68 Mn |
| Sep 30, 2023 | -542.01 Mn |
| Jun 30, 2023 | -406.60 Mn |
| Mar 31, 2023 | -358.50 Mn |
| Dec 31, 2022 | -520.12 Mn |
| Sep 30, 2022 | -344.63 Mn |
| Jun 30, 2022 | -426.40 Mn |
| Mar 31, 2022 | -320.76 Mn |
| Dec 31, 2021 | -310.59 Mn |
| Sep 30, 2021 | -307.09 Mn |
| Jun 30, 2021 | -242.18 Mn |
| Mar 31, 2021 | -260.79 Mn |