BioNTech SE (BNTX) Research & Development (2018 - 2025)
BioNTech SE (BNTX) posted Research & Development of -$588.3 million for Q4 2025, up 10.9% sequentially from -$660.3 million in Q3 2025, and up 10.01% YoY from -$534.8 million in Q4 2024.
BioNTech SE (BNTX) Research & Development (2018 - 2025) Analysis & Trends
BioNTech SE has reported Research & Development for 8 years, with the latest figure at -$588.3 million in Q4 2025.
- Quarterly Research & Development rose 10.01% year-over-year to -$588.3 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was -$2.4 billion (up 2.51% YoY) and the FY2025 annual result came in at $2.4 billion, down 1.27% from the prior year.
- Research & Development improved to -$588.3 million in Q4 2025 per BNTX's latest filing, from -$660.3 million in the prior quarter.
- Over five years, Research & Development peaked at -$242.2 million in Q2 2021 and troughed at -$660.3 million in Q3 2025.
- A 5-year average of -$473.9 million and a median of -$531.1 million in 2022 frame the typical range for Research & Development.
- The sharpest annual moves came in 2021 and 2025: Research & Development sank 101360660.56% in 2021, then grew 10.01% in 2025.
- Over 5 years, Research & Development stood at -$310.6 million in 2021, then plunged by 67.46% to -$520.1 million in 2022, then fell by 19.53% to -$621.7 million in 2023, then decreased by 5.16% to -$653.8 million in 2024, then grew by 10.01% to -$588.3 million in 2025.
- According to Business Quant data, Research & Development over the past three periods registered -$588.3 million, -$660.3 million, and -$576.3 million for Q4 2025, Q3 2025, and Q2 2025 respectively.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | R&D (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 993.80 Mn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 1.63 Bn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | 1.37 Bn |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | 394.92 Mn |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 612.28 Mn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | 1,146.05 |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 97.90 Mn |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 413.13 Mn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | 210.03 Mn |
| 10 | BioNTech SE | 23.54 Bn | 5.15 Bn | 668.28 Mn | -588.31 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -588.31 Mn |
| Sep 30, 2025 | -660.28 Mn |
| Jun 30, 2025 | -576.28 Mn |
| Mar 31, 2025 | -552.87 Mn |
| Dec 31, 2024 | -653.77 Mn |
| Sep 30, 2024 | -604.35 Mn |
| Jun 30, 2024 | -629.55 Mn |
| Mar 31, 2024 | -551.33 Mn |
| Dec 31, 2023 | -621.68 Mn |
| Sep 30, 2023 | -542.01 Mn |
| Jun 30, 2023 | -406.60 Mn |
| Mar 31, 2023 | -358.50 Mn |
| Dec 31, 2022 | -520.12 Mn |
| Sep 30, 2022 | -344.63 Mn |
| Jun 30, 2022 | -426.40 Mn |
| Mar 31, 2022 | -320.76 Mn |
| Dec 31, 2021 | -310.59 Mn |
| Sep 30, 2021 | -307.09 Mn |
| Jun 30, 2021 | -242.18 Mn |
| Mar 31, 2021 | -260.79 Mn |