BioNTech SE (BNTX) Research & Development (2018 - 2025)

BioNTech SE (BNTX) posted Research & Development of -$588.3 million for Q4 2025, up 10.9% sequentially from -$660.3 million in Q3 2025, and up 10.01% YoY from -$534.8 million in Q4 2024.

BioNTech SE (BNTX) Research & Development (2018 - 2025) Analysis & Trends

BioNTech SE has reported Research & Development for 8 years, with the latest figure at -$588.3 million in Q4 2025.

  • Quarterly Research & Development rose 10.01% year-over-year to -$588.3 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was -$2.4 billion (up 2.51% YoY) and the FY2025 annual result came in at $2.4 billion, down 1.27% from the prior year.
  • Research & Development improved to -$588.3 million in Q4 2025 per BNTX's latest filing, from -$660.3 million in the prior quarter.
  • Over five years, Research & Development peaked at -$242.2 million in Q2 2021 and troughed at -$660.3 million in Q3 2025.
  • A 5-year average of -$473.9 million and a median of -$531.1 million in 2022 frame the typical range for Research & Development.
  • The sharpest annual moves came in 2021 and 2025: Research & Development sank 101360660.56% in 2021, then grew 10.01% in 2025.
  • Over 5 years, Research & Development stood at -$310.6 million in 2021, then plunged by 67.46% to -$520.1 million in 2022, then fell by 19.53% to -$621.7 million in 2023, then decreased by 5.16% to -$653.8 million in 2024, then grew by 10.01% to -$588.3 million in 2025.
  • According to Business Quant data, Research & Development over the past three periods registered -$588.3 million, -$660.3 million, and -$576.3 million for Q4 2025, Q3 2025, and Q2 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) R&D (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 993.80 Mn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 1.63 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 1.37 Bn
4 Revolution Medicines 43.64 Bn 43.64 Bn - 394.92 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 612.28 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 1,146.05
7 Royalty Pharma 33.72 Bn 35.84 Bn - 97.90 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 413.13 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn 210.03 Mn
10 BioNTech SE 23.54 Bn 5.15 Bn 668.28 Mn -588.31 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -588.31 Mn
Sep 30, 2025 -660.28 Mn
Jun 30, 2025 -576.28 Mn
Mar 31, 2025 -552.87 Mn
Dec 31, 2024 -653.77 Mn
Sep 30, 2024 -604.35 Mn
Jun 30, 2024 -629.55 Mn
Mar 31, 2024 -551.33 Mn
Dec 31, 2023 -621.68 Mn
Sep 30, 2023 -542.01 Mn
Jun 30, 2023 -406.60 Mn
Mar 31, 2023 -358.50 Mn
Dec 31, 2022 -520.12 Mn
Sep 30, 2022 -344.63 Mn
Jun 30, 2022 -426.40 Mn
Mar 31, 2022 -320.76 Mn
Dec 31, 2021 -310.59 Mn
Sep 30, 2021 -307.09 Mn
Jun 30, 2021 -242.18 Mn
Mar 31, 2021 -260.79 Mn