BioNTech SE (BNTX) Research & Development (2018 - 2025)

BioNTech SE's (BNTX) quarterly Research & Development came in at -$588.3 million in Q4 2025, up 10.01% year-on-year from -$534.8 million in Q4 2024, and up 10.9% quarter-over-quarter from -$660.3 million in Q3 2025.

BioNTech SE (BNTX) Research & Development (2018 - 2025) Analysis & Trends

BioNTech SE has disclosed Research & Development across 8 years of filings, most recently posting -$588.3 million for Q4 2025.

  • Research & Development for Q4 2025 came in at -$588.3 million, up 10.01% year-over-year; the trailing twelve-month figure through Dec 2025 was -$2.4 billion (up 2.51% YoY), and the FY2025 annual result was -$2.4 billion, up 1.27% from the prior year.
  • Research & Development came in at -$588.3 million for Q4 2025 at BioNTech SE, up from -$660.3 million in the prior quarter.
  • In the past five years, Research & Development ranged from a high of -$242.2 million in Q2 2021 to a low of -$660.3 million in Q3 2025.
  • The 5-year median for Research & Development is -$531.1 million (2022), against an average of -$473.9 million.
  • Across the five-year window, Research & Development sank 101360660.56% in 2021 and advanced 10.01% in 2025, its largest moves.
  • BioNTech SE's Research & Development stood at -$310.6 million in 2021, then plunged by 67.46% to -$520.1 million in 2022, then dropped by 19.53% to -$621.7 million in 2023, then fell by 5.16% to -$653.8 million in 2024, then advanced by 10.01% to -$588.3 million in 2025.
  • The last three Research & Development figures came in at -$588.3 million (Q4 2025), -$660.3 million (Q3 2025), and -$576.3 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) R&D (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - 4.32 Mn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - 15.66 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 626,092.00
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -101.30 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -2.30 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - 1.46 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - 357,444.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 961.60 Mn
9 Abivax 91.96 Bn 91.96 Bn - -58.00 Mn
10 BioNTech SE 27.38 Bn 10.07 Bn 668.28 Mn -588.31 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -588.31 Mn
Sep 30, 2025 -660.28 Mn
Jun 30, 2025 -576.28 Mn
Mar 31, 2025 -552.87 Mn
Dec 31, 2024 -653.77 Mn
Sep 30, 2024 -604.35 Mn
Jun 30, 2024 -629.55 Mn
Mar 31, 2024 -551.33 Mn
Dec 31, 2023 -621.68 Mn
Sep 30, 2023 -542.01 Mn
Jun 30, 2023 -406.60 Mn
Mar 31, 2023 -358.50 Mn
Dec 31, 2022 -520.12 Mn
Sep 30, 2022 -344.63 Mn
Jun 30, 2022 -426.40 Mn
Mar 31, 2022 -320.76 Mn
Dec 31, 2021 -310.59 Mn
Sep 30, 2021 -307.09 Mn
Jun 30, 2021 -242.18 Mn
Mar 31, 2021 -260.79 Mn