BioNTech SE (BNTX) EBITDA Margin (2018 - 2025)
BioNTech SE (BNTX) posted EBITDA Margin of 35.57% for Q4 2025, down 1052.1% on a QoQ basis from 3.09% in Q3 2025, and down 4806.0% year-over-year from 0.76% in Q4 2024.
BioNTech SE (BNTX) has 8 years of EBITDA Margin data on file, last reported at 35.57% in Q4 2025.
- In Q4 2025, EBITDA Margin fell 4806.0% year-over-year to 35.57%; the TTM figure through Dec 2025 stood at 42.64% (down 998.0% YoY), while the FY2025 annual figure was 48.95%, up 119095.0% from the prior year.
- EBITDA Margin slipped to 35.57% in Q4 2025, from 3.09% in the prior quarter.
- Across five years, EBITDA Margin topped out at 84.95% in Q4 2021 and bottomed at 2790.85% in Q2 2024.
- A 5-year average of 150.13% and a median of 26.28% in 2023 frame the typical range for EBITDA Margin.
- Annual changes were most pronounced in 2024 — EBITDA Margin tumbled 245496 bps — and 2025, when it jumped 262789 bps.
- Year by year, EBITDA Margin stood at 84.95% in 2021, then decreased by 9 bps to 76.97% in 2022, then tumbled by 54 bps to 35.58% in 2023, then plunged by 65 bps to 12.49% in 2024, then plunged by 385 bps to 35.57% in 2025.
- The last three EBITDA Margin figures came in at 35.57% (Q4 2025), 3.09% (Q3 2025), and 162.96% (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | - |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | -6.43% |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | - |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 38.10% |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 18.35% |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 17.24% |
| 10 | BioNTech SE | 27.66 Bn | 7.53 Bn | 668.28 Mn | -35.57% |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -35.57% |
| Sep 30, 2025 | -3.09% |
| Jun 30, 2025 | -162.96% |
| Mar 31, 2025 | -2,063.79% |
| Dec 31, 2024 | 4,503.03% |
| Sep 30, 2024 | 15.01% |
| Jun 30, 2024 | -2,790.85% |
| Mar 31, 2024 | -3,182.61% |
| Dec 31, 2023 | 35.58% |
| Sep 30, 2023 | 16.98% |
| Jun 30, 2023 | -335.90% |
| Mar 31, 2023 | 51.25% |
| Dec 31, 2022 | 76.97% |
| Sep 30, 2022 | 68.98% |
| Jun 30, 2022 | 69.13% |
| Mar 31, 2022 | 74.56% |
| Dec 31, 2021 | 84.95% |
| Sep 30, 2021 | 77.60% |
| Jun 30, 2021 | 79.09% |
| Mar 31, 2021 | 81.15% |
| Dec 31, 2020 | 70.70% |
| Sep 30, 2020 | 276.15% |
| Jun 30, 2020 | 193.72% |
| Mar 31, 2020 | 214.08% |
| Sep 30, 2019 | 128.65% |
| Jun 30, 2019 | 185.64% |
| Mar 31, 2019 | 167.60% |
| Dec 31, 2018 | 0.08% |
| Sep 30, 2018 | 0.00% |