Biofrontera (BFRI) Return on Capital Employed (2021 - 2025)
Biofrontera (BFRI) recorded quarterly Return on Capital Employed of 112.39% in Q4 2025, up 66.66% quarter-over-quarter from 337.12% in Q3 2025, and up 9527.0% on a YoY basis from 1.17% in Q4 2024.
Biofrontera (BFRI) Return on Capital Employed (2021 - 2025) Analysis & Trends
Biofrontera's Return on Capital Employed history runs 5 years deep, the most recent figure standing at 112.39% for Q4 2025.
- In Q4 2025, Return on Capital Employed rose 9527.0% year-over-year to 112.39%; the TTM figure through Dec 2025 stood at 112.39% (up 9527.0% YoY), while the FY2025 annual figure was 84.45%, up 4798.0% from the prior year.
- Return on Capital Employed was 112.39% for Q4 2025 at Biofrontera, up from 337.12% in the prior quarter.
- In the past five years, Return on Capital Employed ranged from a high of 1232.83% in Q2 2025 to a low of 337.12% in Q3 2025.
- Historically, Return on Capital Employed has averaged 51.48% across 5 years, with a median of 123.19% in 2021.
- Biggest YoY gain for Return on Capital Employed was 137061 bps in 2025; the steepest drop was 12228 bps in 2025.
- A 5-year view of Return on Capital Employed shows it stood at 123.19% in 2021, then surged by 53 bps to 57.8% in 2022, then sank by 203 bps to 175.38% in 2023, then fell by 18 bps to 207.66% in 2024, then surged by 46 bps to 112.39% in 2025.
- The last three Return on Capital Employed figures came in at 112.39% (Q4 2025), 337.12% (Q3 2025), and 1232.83% (Q2 2025), per Business Quant data.
Powered by 
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROCE (Qtr) |
|---|---|---|---|---|---|
| 1 | Teva Pharmaceutical Industries | 39.72 Bn | 35.98 Bn | 1.97 Bn | 8.52% |
| 2 | Zoetis | 34.61 Bn | 32.67 Bn | 1.62 Bn | 27.58% |
| 3 | United Therapeutics | 24.07 Bn | 21.91 Bn | 648.10 Mn | 21.43% |
| 4 | Aurora Cannabis | 16.98 Bn | 16.91 Bn | 33.43 Mn | - |
| 5 | Neurocrine Biosciences | 16.64 Bn | 15.32 Bn | 800.70 Mn | 20.04% |
| 6 | Elanco Animal Health | 12.19 Bn | 11.76 Bn | 785.00 Mn | 7.34% |
| 7 | Alkermes | 7.37 Bn | 6.86 Bn | -116.06 Mn | 6.92% |
| 8 | Hims & Hers Health | 6.62 Bn | 5.87 Bn | 396.79 Mn | -1.92% |
| 9 | Lantheus Holdings | 6.47 Bn | 5.97 Bn | 230.92 Mn | 14.85% |
| 10 | Biofrontera | 8.65 Mn | 2.24 Mn | 14.09 Mn | -112.39% |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -112.39% |
| Sep 30, 2025 | -337.12% |
| Jun 30, 2025 | 1,232.83% |
| Mar 31, 2025 | -194.26% |
| Dec 31, 2024 | -207.66% |
| Sep 30, 2024 | -214.83% |
| Jun 30, 2024 | -137.78% |
| Mar 31, 2024 | -185.40% |
| Dec 31, 2023 | -175.38% |
| Mar 31, 2023 | -80.56% |
| Dec 31, 2022 | -57.80% |
| Sep 30, 2022 | -39.95% |
| Jun 30, 2022 | -74.79% |
| Mar 31, 2022 | -63.84% |
| Dec 31, 2021 | -123.19% |