Bicycle Therapeutics (BCYC) Return on Sales [ROS] (2018 - 2026)
Bicycle Therapeutics (BCYC) posted Return on Sales [ROS] of -8673.93% for Q2 2026, down 5708.10 percentage points from -2965.82% a year earlier and down 1291.51 percentage points from the prior quarter.
Bicycle Therapeutics (BCYC) Return on Sales [ROS] (2018 - 2026) Analysis & Trends
For the trailing twelve months through Jun 30, 2026, Return on Sales [ROS] at Bicycle Therapeutics was -343.60%, up 1151.73 percentage points year-over-year; for FY2025, it came in at -340.38%, up 254.58 percentage points from FY2024.
- Annual Return on Sales [ROS] has increased for three consecutive years, with a five-year change of +159.72 percentage points (FY2020 to FY2025).
- In prior years, Bicycle Therapeutics' Return on Sales [ROS] was -594.96% in FY2024 (+109.17 pp), -704.13% in FY2023 (+102.43 pp), -806.56% in FY2022 (-245.58 pp) and -560.98% in FY2021 (-60.89 pp).
- The Q2 2026 figure stands as the lowest quarterly Return on Sales [ROS] in data going back to Q1 2018.
- On a year-over-year basis, Return on Sales [ROS] increased in two of the last eight quarters, with an average year-over-year change of -1754.92 percentage points.
- The strongest year-over-year quarter for Return on Sales [ROS] in the past five years was Q3 2025, with a gain of 1827.23 percentage points; the weakest was Q1 2026, with a drop of 6678.75 percentage points.
- According to Business Quant data, Return on Sales [ROS] for the three prior quarters was -7382.41% (Q1 2026), -51.52% (Q4 2025) and -558.64% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROS (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 34.46% |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 24.35% |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | 36.01% |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 30.74% |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 29.12% |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 35.79% |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | 41.71% |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 32.98% |
| 10 | Bicycle Therapeutics | 258.27 Mn | -1.91 Bn | - | -39.57% |
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | -39.57% |
| Jun 30, 2026 | -8,673.93% |
| Mar 31, 2026 | -7,382.41% |
| Dec 31, 2025 | -51.52% |
| Sep 30, 2025 | -558.64% |
| Jun 30, 2025 | -2,965.82% |
| Mar 31, 2025 | -703.66% |
| Dec 31, 2024 | -1,824.78% |
| Sep 30, 2024 | -2,385.87% |
| Jun 30, 2024 | -498.31% |
| Mar 31, 2024 | -162.40% |
| Dec 31, 2023 | -1,017.35% |
| Sep 30, 2023 | -949.12% |
| Jun 30, 2023 | -378.27% |
| Mar 31, 2023 | -853.82% |
| Dec 31, 2022 | -1,011.33% |
| Sep 30, 2022 | -978.91% |
| Jun 30, 2022 | -623.57% |
| Mar 31, 2022 | -709.40% |
| Dec 31, 2021 | -477.96% |
Bicycle Therapeutics Return on Sales [ROS] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-sales-%5Bros%5D&ticker=BCYC&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-sales-[ros]", "ticker": "BCYC", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-sales-%5Bros%5D&ticker=BCYC&period=max&api_key=YOUR_API_KEY");
const data = await res.json();