Bicycle Therapeutics (BCYC) Return on Sales [ROS] (2018 - 2026)
Bicycle Therapeutics (BCYC) posted Return on Sales [ROS] of -8673.93% for Q2 2026, down 5708.10 percentage points from -2965.82% a year earlier and down 1291.51 percentage points from the prior quarter.
Bicycle Therapeutics (BCYC) Return on Sales [ROS] (2018 - 2026) Analysis & Trends
For the trailing twelve months through Jun 30, 2026, Return on Sales [ROS] at Bicycle Therapeutics was -343.60%, up 1151.73 percentage points year-over-year; for FY2025, it came in at -340.38%, up 254.58 percentage points from FY2024.
- Annual Return on Sales [ROS] has increased for three consecutive years, with a five-year change of +159.72 percentage points (FY2020 to FY2025).
- In prior years, Bicycle Therapeutics' Return on Sales [ROS] was -594.96% in FY2024 (+109.17 pp), -704.13% in FY2023 (+102.43 pp), -806.56% in FY2022 (-245.58 pp) and -560.98% in FY2021 (-60.89 pp).
- The Q2 2026 figure stands as the lowest quarterly Return on Sales [ROS] in data going back to Q1 2018.
- On a year-over-year basis, Return on Sales [ROS] increased in two of the last eight quarters, with an average year-over-year change of -1754.92 percentage points.
- The strongest year-over-year quarter for Return on Sales [ROS] in the past five years was Q3 2025, with a gain of 1827.23 percentage points; the weakest was Q1 2026, with a drop of 6678.75 percentage points.
- According to Business Quant data, Return on Sales [ROS] for the three prior quarters was -7382.41% (Q1 2026), -51.52% (Q4 2025) and -558.64% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROS (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,076.25 Bn | 1,044.84 Bn | 19.71 Bn | 51.16% |
| 2 | Johnson & Johnson | 617.18 Bn | 535.70 Bn | 17.26 Bn | 28.21% |
| 3 | AbbVie | 464.58 Bn | 437.73 Bn | 12.70 Bn | 37.86% |
| 4 | Merck | 356.04 Bn | 310.47 Bn | 12.21 Bn | -3.52% |
| 5 | Novartis Ag | 269.07 Bn | 224.94 Bn | 11.24 Bn | 32.97% |
| 6 | Astrazeneca | 243.21 Bn | 216.77 Bn | 12.86 Bn | 20.57% |
| 7 | Amgen | 217.88 Bn | 173.28 Bn | 7.24 Bn | 34.95% |
| 8 | Gilead Sciences | 179.62 Bn | 153.74 Bn | 6.22 Bn | -133.21% |
| 9 | Pfizer | 158.45 Bn | 105.40 Bn | 10.94 Bn | 28.37% |
| 10 | Bicycle Therapeutics | 235.97 Mn | 235.97 Mn | - | -8,673.93% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -8,673.93% |
| Mar 31, 2026 | -7,382.41% |
| Dec 31, 2025 | -51.52% |
| Sep 30, 2025 | -558.64% |
| Jun 30, 2025 | -2,965.82% |
| Mar 31, 2025 | -703.66% |
| Dec 31, 2024 | -1,824.78% |
| Sep 30, 2024 | -2,385.87% |
| Jun 30, 2024 | -498.31% |
| Mar 31, 2024 | -162.40% |
| Dec 31, 2023 | -1,017.35% |
| Sep 30, 2023 | -949.12% |
| Jun 30, 2023 | -378.27% |
| Mar 31, 2023 | -853.82% |
| Dec 31, 2022 | -1,011.33% |
| Sep 30, 2022 | -978.91% |
| Jun 30, 2022 | -623.57% |
| Mar 31, 2022 | -709.40% |
| Dec 31, 2021 | -477.96% |
| Sep 30, 2021 | -329.89% |
Bicycle Therapeutics Return on Sales [ROS] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-sales-%5Bros%5D&ticker=BCYC&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-sales-[ros]", "ticker": "BCYC", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-sales-%5Bros%5D&ticker=BCYC&period=max&api_key=YOUR_API_KEY");
const data = await res.json();