Bicycle Therapeutics (BCYC) Net Margin (2018 - 2026)

Bicycle Therapeutics (BCYC) reported Net Margin of 6857.38% for Q1 2026, down 624844.0% on a YoY basis from N/an in Q1 2025, and down 16216.66% quarter-over-quarter from 42.03% in Q4 2025.

Bicycle Therapeutics (BCYC) Net Margin (2018 - 2026) Analysis & Trends

Bicycle Therapeutics has reported Net Margin for 9 years, with the latest figure at 6857.38% in Q1 2026.

  • For the quarter ending Q1 2026, Net Margin fell 624844.0% year-over-year to 6857.38%; the trailing twelve-month figure through Mar 2026 stood at 344.95% (up 44512.0% YoY), and the FY2025 full-year result was 301.66%, up 17752.0% from the prior year.
  • Net Margin for Q1 2026 stood at 6857.38%, down from 42.03% in the prior quarter.
  • The five-year high for Net Margin was 42.03% in Q4 2025, with the low at 6857.38% in Q1 2026.
  • Historically, Net Margin has averaged 1178.9% across 5 years, with a median of 714.09% in 2022.
  • Annual changes were most pronounced in 2025 — Net Margin surged 139477 bps — and 2026, when it slumped 624844 bps.
  • Bicycle Therapeutics' Net Margin stood at 356.88% in 2022, then tumbled by 158 bps to 921.01% in 2023, then slumped by 52 bps to 1398.44% in 2024, then surged by 97 bps to 42.03% in 2025, then tumbled by 16217 bps to 6857.38% in 2026.
  • The last three Net Margin figures came in at 6857.38% (Q1 2026), 42.03% (Q4 2025), and 503.66% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 0.82%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 34.53%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Bicycle Therapeutics 278.04 Mn 278.04 Mn - -6,857.38%

Historic Data

Download Data
DateValue
Mar 31, 2026 -6,857.38%
Dec 31, 2025 -42.03%
Sep 30, 2025 -503.66%
Jun 30, 2025 -2,703.84%
Mar 31, 2025 -608.94%
Dec 31, 2024 -1,398.44%
Sep 30, 2024 -1,898.43%
Jun 30, 2024 -425.30%
Mar 31, 2024 -255.41%
Dec 31, 2023 -921.01%
Sep 30, 2023 -932.32%
Jun 30, 2023 -373.81%
Mar 31, 2023 -797.88%
Dec 31, 2022 -356.88%
Sep 30, 2022 -932.47%
Jun 30, 2022 -319.38%
Mar 31, 2022 -714.09%
Dec 31, 2021 -1,127.31%
Sep 30, 2021 -338.75%
Jun 30, 2021 -1,003.53%