Bicycle Therapeutics (BCYC) Net Margin (2018 - 2026)
Bicycle Therapeutics (BCYC) posted Net Margin of 6857.38% for Q1 2026, down 16216.66% on a QoQ basis from 42.03% in Q4 2025, and down 624844.0% year-over-year from N/an in Q1 2025.
Bicycle Therapeutics (BCYC) Net Margin (2018 - 2026) Analysis & Trends
Bicycle Therapeutics' Net Margin history runs 9 years deep, the most recent figure standing at 6857.38% for Q1 2026.
- Quarterly Net Margin fell 624844.0% year-over-year to 6857.38% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 344.95% (up 44512.0% YoY) and the FY2025 annual result came in at 301.66%, up 17752.0% from the prior year.
- Net Margin was 6857.38% for Q1 2026 at Bicycle Therapeutics, down from 42.03% in the prior quarter.
- Across five years, Net Margin topped out at 42.03% in Q4 2025 and bottomed at 6857.38% in Q1 2026.
- A 5-year average of 1189.89% and a median of 714.09% in 2022 frame the typical range for Net Margin.
- Annual changes were most pronounced in 2025 — Net Margin surged 139477 bps — and 2026, when it sank 624844 bps.
- Bicycle Therapeutics' Net Margin stood at 356.88% in 2022, then sank by 158 bps to 921.01% in 2023, then plunged by 52 bps to 1398.44% in 2024, then jumped by 97 bps to 42.03% in 2025, then sank by 16217 bps to 6857.38% in 2026.
- Business Quant data shows BCYC's Net Margin at 6857.38% in Q1 2026, 42.03% in Q4 2025, and 503.66% in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | - |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 15.02% |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 34.53% |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 20.17% |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 30.33% |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | - |
| 10 | Bicycle Therapeutics | 289.88 Mn | 289.88 Mn | - | -6,857.38% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -6,857.38% |
| Dec 31, 2025 | -42.03% |
| Sep 30, 2025 | -503.66% |
| Jun 30, 2025 | -2,703.84% |
| Mar 31, 2025 | -608.94% |
| Dec 31, 2024 | -1,398.44% |
| Sep 30, 2024 | -1,898.43% |
| Jun 30, 2024 | -425.30% |
| Mar 31, 2024 | -255.41% |
| Dec 31, 2023 | -921.01% |
| Sep 30, 2023 | -932.32% |
| Jun 30, 2023 | -373.81% |
| Mar 31, 2023 | -797.88% |
| Dec 31, 2022 | -356.88% |
| Sep 30, 2022 | -932.47% |
| Jun 30, 2022 | -506.19% |
| Mar 31, 2022 | -714.09% |
| Dec 31, 2021 | -1,127.31% |
| Sep 30, 2021 | -338.75% |
| Jun 30, 2021 | -1,003.53% |