Bicycle Therapeutics (BCYC) Net Margin (2018 - 2026)
Bicycle Therapeutics posted quarterly Net Margin of 6857.38% for Q1 2026, down 624844.0% year-on-year from N/an in Q1 2025, and down 16216.66% on a QoQ basis from 42.03% in Q4 2025.
Bicycle Therapeutics (BCYC) has 9 years of Net Margin data on file, last reported at 6857.38% in Q1 2026.
- For the quarter ending Q1 2026, Net Margin fell 624844.0% year-over-year to 6857.38%; the trailing twelve-month figure through Mar 2026 stood at 344.95% (up 44512.0% YoY), and the FY2025 full-year result was 301.66%, up 17752.0% from the prior year.
- Net Margin for Q1 2026 stood at 6857.38%, down from 42.03% in the prior quarter.
- Across five years, Net Margin topped out at 42.03% in Q4 2025 and bottomed at 6857.38% in Q1 2026.
- The 5-year median for Net Margin is 714.09% (2022), against an average of 1178.9%.
- The widest annual swing landed in 2025, when Net Margin surged 139477 bps; it then plunged 624844 bps in 2026.
- A 5-year view of Net Margin shows it stood at 356.88% in 2022, then slumped by 158 bps to 921.01% in 2023, then sank by 52 bps to 1398.44% in 2024, then soared by 97 bps to 42.03% in 2025, then slumped by 16217 bps to 6857.38% in 2026.
- The last three Net Margin figures came in at 6857.38% (Q1 2026), 42.03% (Q4 2025), and 503.66% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 1,216,509.61 Bn | 1,216,509.61 Bn | - | - |
| 2 | Alterity Therapeutics | 764,224.41 Bn | 764,224.38 Bn | - | - |
| 3 | Legend Biotech | 2,716.00 Bn | 2,715.71 Bn | 242.10 Mn | 0.82% |
| 4 | Nanobiotix | 2,248.83 Bn | 2,248.77 Bn | - | - |
| 5 | Akari Therapeutics | 1,951.18 Bn | 1,951.17 Bn | - | - |
| 6 | Vertex Pharmaceuticals | 113.69 Bn | 106.44 Bn | 2.59 Bn | 34.53% |
| 7 | Evaxion A | 64.16 Bn | 64.14 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 63.94 Bn | 55.18 Bn | 3.31 Bn | 20.17% |
| 9 | Alnylam Pharmaceuticals | 40.13 Bn | 37.12 Bn | 959.66 Mn | 17.65% |
| 10 | Bicycle Therapeutics | 326.82 Mn | 326.82 Mn | - | -6,857.38% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -6,857.38% |
| Dec 31, 2025 | -42.03% |
| Sep 30, 2025 | -503.66% |
| Jun 30, 2025 | -2,703.84% |
| Mar 31, 2025 | -608.94% |
| Dec 31, 2024 | -1,398.44% |
| Sep 30, 2024 | -1,898.43% |
| Jun 30, 2024 | -425.30% |
| Mar 31, 2024 | -255.41% |
| Dec 31, 2023 | -921.01% |
| Sep 30, 2023 | -932.32% |
| Jun 30, 2023 | -373.81% |
| Mar 31, 2023 | -797.88% |
| Dec 31, 2022 | -356.88% |
| Sep 30, 2022 | -932.47% |
| Jun 30, 2022 | -319.38% |
| Mar 31, 2022 | -714.09% |
| Dec 31, 2021 | -1,127.31% |
| Sep 30, 2021 | -338.75% |
| Jun 30, 2021 | -1,003.53% |
| Mar 31, 2021 | -895.52% |
| Dec 31, 2020 | -453.04% |
| Sep 30, 2020 | -263.87% |
| Jun 30, 2020 | -771.16% |
| Mar 31, 2020 | -1,003.01% |
| Dec 31, 2019 | -83.43% |
| Sep 30, 2019 | -1,544.30% |
| Jun 30, 2019 | -671.29% |
| Mar 31, 2019 | -101.86% |
| Dec 31, 2018 | -628.29% |
| Sep 30, 2018 | -477.76% |
| Jun 30, 2018 | -299.76% |
| Mar 31, 2018 | -90.24% |