Bicycle Therapeutics (BCYC) Net Cash Flow (2018 - 2026)
Bicycle Therapeutics posted quarterly Net Cash Flow of -$66.7 million for Q1 2026, up 23.36% year-on-year from -$54.1 million in Q1 2025, and down 234.55% on a QoQ basis from -$19.9 million in Q4 2025.
Bicycle Therapeutics (BCYC) has 9 years of Net Cash Flow data on file, last reported at -$66.7 million in Q1 2026.
- For the quarter ending Q1 2026, Net Cash Flow rose 23.36% year-over-year to -$66.7 million; the trailing twelve-month figure through Mar 2026 stood at -$231.8 million (down 169.04% YoY), and the FY2025 full-year result was -$252.2 million, down 171.27% from the prior year.
- Net Cash Flow for Q1 2026 stood at -$66.7 million, down from -$19.9 million in the prior quarter.
- Across five years, Net Cash Flow topped out at $504.6 million in Q2 2024 and bottomed at -$87.0 million in Q1 2025.
- The 5-year median for Net Cash Flow is -$33.1 million (2022), against an average of $7.2 million.
- The widest annual swing landed in 2022, when Net Cash Flow slumped 1200.46%; it then surged 2780.59% in 2023.
- A 5-year view of Net Cash Flow shows it stood at -$25.9 million in 2022, then sank by 81.5% to -$47.0 million in 2023, then soared by 79.64% to -$9.6 million in 2024, then tumbled by 108.5% to -$19.9 million in 2025, then sank by 234.55% to -$66.7 million in 2026.
- The last three Net Cash Flow figures came in at -$66.7 million (Q1 2026), -$19.9 million (Q4 2025), and -$71.9 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Cash Flow (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 1,216,509.61 Bn | 1,216,509.61 Bn | - | 2.44 Mn |
| 2 | Alterity Therapeutics | 764,224.41 Bn | 764,224.38 Bn | - | - |
| 3 | Legend Biotech | 2,716.00 Bn | 2,715.71 Bn | 242.10 Mn | 625.70 Mn |
| 4 | Nanobiotix | 2,248.83 Bn | 2,248.77 Bn | - | - |
| 5 | Akari Therapeutics | 1,951.18 Bn | 1,951.17 Bn | - | -2.44 Mn |
| 6 | Vertex Pharmaceuticals | 113.69 Bn | 106.44 Bn | 2.59 Bn | 457.40 Mn |
| 7 | Evaxion A | 64.16 Bn | 64.14 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 63.94 Bn | 55.18 Bn | 3.31 Bn | -152.20 Mn |
| 9 | Alnylam Pharmaceuticals | 40.13 Bn | 37.12 Bn | 959.66 Mn | 60.68 Mn |
| 10 | Bicycle Therapeutics | 326.82 Mn | 326.82 Mn | - | -66.69 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -66.69 Mn |
| Mar 31, 2026 | -66.69 Mn |
| Dec 31, 2025 | -19.94 Mn |
| Dec 31, 2025 | -19.94 Mn |
| Sep 30, 2025 | -71.88 Mn |
| Sep 30, 2025 | -71.88 Mn |
| Jun 30, 2025 | -73.33 Mn |
| Jun 30, 2025 | -73.33 Mn |
| Mar 31, 2025 | -87.02 Mn |
| Mar 31, 2025 | -87.02 Mn |
| Dec 31, 2024 | -9.56 Mn |
| Dec 31, 2024 | -9.56 Mn |
| Sep 30, 2024 | -72.20 Mn |
| Sep 30, 2024 | -72.20 Mn |
| Jun 30, 2024 | 504.56 Mn |
| Jun 30, 2024 | 504.56 Mn |
| Mar 31, 2024 | -69.01 Mn |
| Mar 31, 2024 | -69.01 Mn |
| Dec 31, 2023 | -46.95 Mn |
| Dec 31, 2023 | -46.95 Mn |
| Sep 30, 2023 | 233.10 Mn |
| Sep 30, 2023 | 233.10 Mn |
| Jun 30, 2023 | 46.11 Mn |
| Jun 30, 2023 | 46.11 Mn |
| Mar 31, 2023 | -45.79 Mn |
| Mar 31, 2023 | -45.79 Mn |
| Dec 31, 2022 | -25.87 Mn |
| Dec 31, 2022 | -25.87 Mn |
| Sep 30, 2022 | -8.70 Mn |
| Sep 30, 2022 | -8.70 Mn |
| Jun 30, 2022 | -33.14 Mn |
| Jun 30, 2022 | -33.14 Mn |
| Mar 31, 2022 | -30.71 Mn |
| Mar 31, 2022 | -30.71 Mn |
| Dec 31, 2021 | 179.16 Mn |
| Dec 31, 2021 | 179.16 Mn |
| Sep 30, 2021 | 62.00 Mn |
| Sep 30, 2021 | 62.00 Mn |
| Jun 30, 2021 | 3.01 Mn |
| Jun 30, 2021 | 3.01 Mn |
| Mar 31, 2021 | 59.73 Mn |
| Mar 31, 2021 | 59.73 Mn |
| Dec 31, 2020 | -15.36 Mn |
| Dec 31, 2020 | -15.36 Mn |
| Sep 30, 2020 | 51.01 Mn |
| Sep 30, 2020 | 51.01 Mn |
| Jun 30, 2020 | -12.64 Mn |
| Jun 30, 2020 | -12.64 Mn |
| Mar 31, 2020 | 20.84 Mn |
| Mar 31, 2020 | 20.84 Mn |
| Dec 31, 2019 | -5.19 Mn |
| Dec 31, 2019 | -5.19 Mn |
| Sep 30, 2019 | -11.98 Mn |
| Sep 30, 2019 | -11.98 Mn |
| Jun 30, 2019 | 51.02 Mn |
| Jun 30, 2019 | 51.02 Mn |
| Mar 31, 2019 | -5.59 Mn |
| Mar 31, 2019 | -5.59 Mn |
| Dec 31, 2018 | 16.17 Mn |
| Dec 31, 2018 | 16.17 Mn |
| Sep 30, 2018 | -4.78 Mn |
| Sep 30, 2018 | -4.78 Mn |