Bicycle Therapeutics (BCYC) Net Cash Flow (2018 - 2026)

Bicycle Therapeutics' (BCYC) quarterly Net Cash Flow came in at -$49.9 million in Q2 2026, up 31.92% YoY from -$37.8 million in Q2 2025, and up 25.15% on a QoQ basis from -$66.7 million in Q1 2026.

Bicycle Therapeutics (BCYC) Net Cash Flow (2018 - 2026) Analysis & Trends

Bicycle Therapeutics (BCYC) has 9 years of Net Cash Flow data on file, last reported at -$49.9 million in Q2 2026.

  • Quarterly Net Cash Flow rose 31.92% year-over-year to -$49.9 million in Q2 2026, while the trailing twelve-month figure through Jun 2026 was -$208.4 million (up 13.91% YoY) and the FY2025 annual result came in at -$252.2 million, down 171.27% from the prior year.
  • Net Cash Flow advanced to -$49.9 million in Q2 2026, from -$66.7 million in the prior quarter.
  • In the past five years, Net Cash Flow ranged from a high of $504.6 million in Q2 2024 to a low of -$87.0 million in Q1 2025.
  • A 5-year average of $4.1 million and a median of -$39.5 million in 2022 frame the typical range for Net Cash Flow.
  • Annual changes were most pronounced in 2022 — Net Cash Flow plunged 1200.46% — and 2023, when it surged 2780.59%.
  • Tracing BCYC's Net Cash Flow over 5 years: stood at -$25.9 million in 2022, then slumped by 81.5% to -$47.0 million in 2023, then surged by 79.64% to -$9.6 million in 2024, then plunged by 108.5% to -$19.9 million in 2025, then slumped by 150.42% to -$49.9 million in 2026.
  • The last three Net Cash Flow figures came in at -$49.9 million (Q2 2026), -$66.7 million (Q1 2026), and -$19.9 million (Q4 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Cash Flow (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 652.90 Mn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn -504.30 Mn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -
4 Revolution Medicines 43.64 Bn 43.64 Bn - 374.50 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 407.41 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 17.81 Mn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 225.59 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn -496,000.00
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -37.14 Mn
10 Bicycle Therapeutics 272.28 Mn 272.28 Mn - -49.92 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -49.92 Mn
Jun 30, 2026 -49.92 Mn
Mar 31, 2026 -66.69 Mn
Mar 31, 2026 -66.69 Mn
Dec 31, 2025 -19.94 Mn
Dec 31, 2025 -19.94 Mn
Sep 30, 2025 -71.88 Mn
Sep 30, 2025 -71.88 Mn
Jun 30, 2025 -73.33 Mn
Jun 30, 2025 -73.33 Mn
Mar 31, 2025 -87.02 Mn
Mar 31, 2025 -87.02 Mn
Dec 31, 2024 -9.56 Mn
Dec 31, 2024 -9.56 Mn
Sep 30, 2024 -72.20 Mn
Sep 30, 2024 -72.20 Mn
Jun 30, 2024 504.56 Mn
Jun 30, 2024 504.56 Mn
Mar 31, 2024 -69.01 Mn
Mar 31, 2024 -69.01 Mn