Bicycle Therapeutics (BCYC) Free Cash Flow (2018 - 2026)

Bicycle Therapeutics (BCYC) posted Free Cash Flow of -$66.6 million for Q1 2026, down 234.53% on a QoQ basis from -$19.9 million in Q4 2025, and up 23.38% year-over-year from -$54.0 million in Q1 2025.

Bicycle Therapeutics (BCYC) Free Cash Flow (2018 - 2026) Analysis & Trends

Bicycle Therapeutics' Free Cash Flow history runs 9 years deep, the most recent figure standing at -$66.6 million for Q1 2026.

  • Quarterly Free Cash Flow rose 23.38% year-over-year to -$66.6 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$231.7 million (down 27.27% YoY) and the FY2025 annual result came in at -$252.0 million, down 51.86% from the prior year.
  • Free Cash Flow was -$66.6 million for Q1 2026 at Bicycle Therapeutics, down from -$19.9 million in the prior quarter.
  • Across five years, Free Cash Flow topped out at $33.8 million in Q2 2023 and bottomed at -$87.0 million in Q1 2025.
  • A 5-year average of -$38.4 million and a median of -$40.3 million in 2024 frame the typical range for Free Cash Flow.
  • Annual changes were most pronounced in 2023 — Free Cash Flow soared 201.47% — and 2024, when it tumbled 2537.0%.
  • Bicycle Therapeutics' Free Cash Flow stood at -$31.8 million in 2022, then sank by 49.07% to -$47.3 million in 2023, then soared by 79.37% to -$9.8 million in 2024, then tumbled by 104.01% to -$19.9 million in 2025, then sank by 234.53% to -$66.6 million in 2026.
  • Business Quant data shows BCYC's Free Cash Flow at -$66.6 million in Q1 2026, -$19.9 million in Q4 2025, and -$71.8 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -19.58 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 158.09 Mn
4 NuCana 279.75 Bn 279.75 Bn - -1.53 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.29 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 848.30 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -354.95 Mn
10 Bicycle Therapeutics 289.88 Mn 289.88 Mn - -66.64 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -66.64 Mn
Mar 31, 2026 -66.64 Mn
Dec 31, 2025 -19.92 Mn
Dec 31, 2025 -19.92 Mn
Sep 30, 2025 -71.85 Mn
Sep 30, 2025 -71.85 Mn
Jun 30, 2025 -73.28 Mn
Jun 30, 2025 -73.28 Mn
Mar 31, 2025 -86.97 Mn
Mar 31, 2025 -86.97 Mn
Dec 31, 2024 -9.76 Mn
Dec 31, 2024 -9.76 Mn
Sep 30, 2024 -40.27 Mn
Sep 30, 2024 -40.27 Mn
Jun 30, 2024 -45.05 Mn
Jun 30, 2024 -45.05 Mn
Mar 31, 2024 -70.88 Mn
Mar 31, 2024 -70.88 Mn
Dec 31, 2023 -47.34 Mn
Dec 31, 2023 -47.34 Mn