Bicycle Therapeutics (BCYC) Free Cash Flow (2018 - 2026)

Bicycle Therapeutics (BCYC) reported Free Cash Flow of -$66.6 million for Q1 2026, up 23.38% on a YoY basis from -$54.0 million in Q1 2025, and down 234.53% quarter-over-quarter from -$19.9 million in Q4 2025.

Bicycle Therapeutics (BCYC) Free Cash Flow (2018 - 2026) Analysis & Trends

Bicycle Therapeutics has reported Free Cash Flow for 9 years, with the latest figure at -$66.6 million in Q1 2026.

  • For the quarter ending Q1 2026, Free Cash Flow rose 23.38% year-over-year to -$66.6 million; the trailing twelve-month figure through Mar 2026 stood at -$231.7 million (down 27.27% YoY), and the FY2025 full-year result was -$252.0 million, down 51.86% from the prior year.
  • Free Cash Flow for Q1 2026 stood at -$66.6 million, down from -$19.9 million in the prior quarter.
  • The five-year high for Free Cash Flow was $33.8 million in Q2 2023, with the low at -$87.0 million in Q1 2025.
  • Historically, Free Cash Flow has averaged -$38.4 million across 5 years, with a median of -$40.3 million in 2024.
  • Annual changes were most pronounced in 2023 — Free Cash Flow soared 201.47% — and 2024, when it plunged 2537.0%.
  • Bicycle Therapeutics' Free Cash Flow stood at -$31.8 million in 2022, then tumbled by 49.07% to -$47.3 million in 2023, then jumped by 79.37% to -$9.8 million in 2024, then sank by 104.01% to -$19.9 million in 2025, then tumbled by 234.53% to -$66.6 million in 2026.
  • The last three Free Cash Flow figures came in at -$66.6 million (Q1 2026), -$19.9 million (Q4 2025), and -$71.8 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -1.67 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -12.20 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -2.49 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.29 Bn
9 Abivax 91.96 Bn 91.96 Bn - 63,220.27
10 Bicycle Therapeutics 278.04 Mn 278.04 Mn - -66.64 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -66.64 Mn
Mar 31, 2026 -66.64 Mn
Dec 31, 2025 -19.92 Mn
Dec 31, 2025 -19.92 Mn
Sep 30, 2025 -71.85 Mn
Sep 30, 2025 -71.85 Mn
Jun 30, 2025 -73.28 Mn
Jun 30, 2025 -73.28 Mn
Mar 31, 2025 -86.97 Mn
Mar 31, 2025 -86.97 Mn
Dec 31, 2024 -9.76 Mn
Dec 31, 2024 -9.76 Mn
Sep 30, 2024 -40.27 Mn
Sep 30, 2024 -40.27 Mn
Jun 30, 2024 -45.05 Mn
Jun 30, 2024 -45.05 Mn
Mar 31, 2024 -70.88 Mn
Mar 31, 2024 -70.88 Mn
Dec 31, 2023 -47.34 Mn
Dec 31, 2023 -47.34 Mn