Bicycle Therapeutics (BCYC) Enterprise Value (2018 - 2026)

Bicycle Therapeutics (BCYC) posted Enterprise Value of -$559.5 million for Q1 2026, up 10.93% on a QoQ basis from -$628.1 million in Q4 2025, and up 29.45% year-over-year from -$432.2 million in Q1 2025.

Bicycle Therapeutics (BCYC) Enterprise Value (2018 - 2026) Analysis & Trends

Bicycle Therapeutics' Enterprise Value history runs 9 years deep, the most recent figure standing at -$559.5 million for Q1 2026.

  • Quarterly Enterprise Value rose 29.45% year-over-year to -$559.5 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$559.5 million (up 29.45% YoY) and the FY2025 annual result came in at -$628.1 million, up 5.53% from the prior year.
  • Enterprise Value was -$559.5 million for Q1 2026 at Bicycle Therapeutics, up from -$628.1 million in the prior quarter.
  • Across five years, Enterprise Value topped out at -$100.0 million in Q1 2022 and bottomed at -$961.4 million in Q2 2024.
  • A 5-year average of -$543.0 million and a median of -$559.5 million in 2026 frame the typical range for Enterprise Value.
  • Annual changes were most pronounced in 2022 — Enterprise Value surged 48.95% — and 2023, when it tumbled 193.81%.
  • Bicycle Therapeutics' Enterprise Value stood at -$339.2 million in 2022, then slumped by 55.22% to -$526.4 million in 2023, then slipped by 26.31% to -$664.9 million in 2024, then advanced by 5.53% to -$628.1 million in 2025, then rose by 10.93% to -$559.5 million in 2026.
  • Business Quant data shows BCYC's Enterprise Value at -$559.5 million in Q1 2026, -$628.1 million in Q4 2025, and -$648.3 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -283.54 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -61.40 Mn
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn -4.79 Bn
4 NuCana 279.75 Bn 279.75 Bn - -32.26 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn -7.25 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn -8.75 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -5.18 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -1.91 Bn
10 Bicycle Therapeutics 289.88 Mn 289.88 Mn - -559.47 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -559.47 Mn
Dec 31, 2025 -628.11 Mn
Sep 30, 2025 -648.30 Mn
Jun 30, 2025 -721.50 Mn
Mar 31, 2025 -792.97 Mn
Dec 31, 2024 -664.90 Mn
Sep 30, 2024 -890.86 Mn
Jun 30, 2024 -961.36 Mn
Mar 31, 2024 -457.00 Mn
Dec 31, 2023 -526.42 Mn
Sep 30, 2023 -572.09 Mn
Jun 30, 2023 -340.43 Mn
Mar 31, 2023 -293.82 Mn
Dec 31, 2022 -339.15 Mn
Sep 30, 2022 -361.47 Mn
Jun 30, 2022 -372.80 Mn
Mar 31, 2022 -100.00 Mn
Dec 31, 2021 -438.68 Mn
Sep 30, 2021 -259.52 Mn
Jun 30, 2021 -198.74 Mn