Bicycle Therapeutics (BCYC) Enterprise Value (2018 - 2026)

Bicycle Therapeutics (BCYC) reported Enterprise Value of -$559.5 million for Q1 2026, up 29.44% on a YoY basis from -$432.2 million in Q1 2025, and up 10.92% quarter-over-quarter from -$628.1 million in Q4 2025.

Bicycle Therapeutics (BCYC) Enterprise Value (2018 - 2026) Analysis & Trends

Bicycle Therapeutics has reported Enterprise Value for 9 years, with the latest figure at -$559.5 million in Q1 2026.

  • For the quarter ending Q1 2026, Enterprise Value rose 29.44% year-over-year to -$559.5 million; the trailing twelve-month figure through Mar 2026 stood at -$559.5 million (up 29.44% YoY), and the FY2025 full-year result was -$628.1 million, up 5.53% from the prior year.
  • Enterprise Value for Q1 2026 stood at -$559.5 million, up from -$628.1 million in the prior quarter.
  • The five-year high for Enterprise Value was -$100.0 million in Q1 2022, with the low at -$961.4 million in Q2 2024.
  • Historically, Enterprise Value has averaged -$543.0 million across 5 years, with a median of -$559.5 million in 2026.
  • Annual changes were most pronounced in 2022 — Enterprise Value surged 48.95% — and 2023, when it plunged 193.81%.
  • Bicycle Therapeutics' Enterprise Value stood at -$339.2 million in 2022, then plunged by 55.22% to -$526.4 million in 2023, then retreated by 26.31% to -$664.9 million in 2024, then rose by 5.53% to -$628.1 million in 2025, then gained by 10.92% to -$559.5 million in 2026.
  • The last three Enterprise Value figures came in at -$559.5 million (Q1 2026), -$628.1 million (Q4 2025), and -$648.3 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -32.30 Mn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -4.14 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -286.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -18.44 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -2.77 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -7.20 Mn
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn -7.25 Bn
9 Abivax 91.96 Bn 91.96 Bn - -584.73 Mn
10 Bicycle Therapeutics 278.04 Mn 278.04 Mn - -559.50 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -559.50 Mn
Dec 31, 2025 -628.11 Mn
Sep 30, 2025 -648.30 Mn
Jun 30, 2025 -721.50 Mn
Mar 31, 2025 -792.97 Mn
Dec 31, 2024 -664.90 Mn
Sep 30, 2024 -890.86 Mn
Jun 30, 2024 -961.36 Mn
Mar 31, 2024 -457.00 Mn
Dec 31, 2023 -526.42 Mn
Sep 30, 2023 -572.09 Mn
Jun 30, 2023 -340.43 Mn
Mar 31, 2023 -293.82 Mn
Dec 31, 2022 -339.15 Mn
Sep 30, 2022 -361.47 Mn
Jun 30, 2022 -372.80 Mn
Mar 31, 2022 -100.00 Mn
Dec 31, 2021 -438.68 Mn
Jun 30, 2021 -198.74 Mn
Mar 31, 2021 -195.90 Mn