Bicycle Therapeutics (BCYC) EBITDA Margin (2018 - 2026)
Bicycle Therapeutics (BCYC) recorded EBITDA Margin of -8504.29% in Q2 2026, down 5596.55 percentage points from -2907.74% a year earlier and down 1249.16 percentage points from the prior quarter.
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Analysis
Bicycle Therapeutics (BCYC) EBITDA Margin (2018 - 2026) Analysis & Trends
On a TTM basis, Bicycle Therapeutics' EBITDA Margin came in at -334.96% as of Jun 30, 2026, up 1123.00 percentage points year-over-year; for FY2025, it was -331.53%, up 243.09 percentage points from FY2024.
- Annual EBITDA Margin has increased for three straight years, with a five-year change of +156.28 percentage points (FY2020 to FY2025).
- Across earlier years, EBITDA Margin came in at -574.62% in FY2024 (+105.24 pp), -679.86% in FY2023 (+101.19 pp), -781.06% in FY2022 (-232.12 pp) and -548.94% in FY2021 (-61.13 pp).
- The Q2 2026 figure is the lowest quarterly EBITDA Margin in data going back to Q2 2018.
- On a year-over-year basis, EBITDA Margin rose in two of the last eight quarters, with an average year-over-year change of -1726.66 percentage points.
- Peak year-over-year performance for EBITDA Margin in the last five years was a gain of 1761.03 percentage points in Q3 2025, against a drop of 6567.85 percentage points in Q1 2026 at the low end.
- Per Business Quant, the preceding three quarters came in at -7255.13% (Q1 2026), -48.74% (Q4 2025) and -543.68% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 35.95% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 49.01% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | 6.02% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | - |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 33.11% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 46.01% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -124.26% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 39.16% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 39.10% |
| 10 | Bicycle Therapeutics | 259.01 Mn | 259.01 Mn | - | -8,504.29% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -8,504.29% |
| Mar 31, 2026 | -7,255.13% |
| Dec 31, 2025 | -48.74% |
| Sep 30, 2025 | -543.68% |
| Jun 30, 2025 | -2,907.74% |
| Mar 31, 2025 | -687.28% |
| Dec 31, 2024 | -1,778.83% |
| Sep 30, 2024 | -2,304.71% |
| Jun 30, 2024 | -480.79% |
| Mar 31, 2024 | -153.91% |
| Dec 31, 2023 | -986.33% |
| Sep 30, 2023 | -917.54% |
| Jun 30, 2023 | -363.83% |
| Mar 31, 2023 | -822.02% |
| Dec 31, 2022 | -967.82% |
| Sep 30, 2022 | -937.34% |
| Jun 30, 2022 | -609.48% |
| Mar 31, 2022 | -698.47% |
| Dec 31, 2021 | -467.17% |
| Sep 30, 2021 | -322.11% |
API Access
Bicycle Therapeutics EBITDA Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda-margin&ticker=BCYC&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda-margin", "ticker": "BCYC", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebitda-margin&ticker=BCYC&period=max&api_key=YOUR_API_KEY");
const data = await res.json();