Bicycle Therapeutics (BCYC) EBITDA Margin (2018 - 2026)
Bicycle Therapeutics posted quarterly EBITDA Margin of 7057.38% for Q1 2026, down 643261.0% year-on-year from N/an in Q1 2025, and down 16664.26% on a QoQ basis from 42.1% in Q4 2025.
Bicycle Therapeutics (BCYC) has 9 years of EBITDA Margin data on file, last reported at 7057.38% in Q1 2026.
- For the quarter ending Q1 2026, EBITDA Margin fell 643261.0% year-over-year to 7057.38%; the trailing twelve-month figure through Mar 2026 stood at 350.97% (up 44176.0% YoY), and the FY2025 full-year result was 306.65%, up 16850.0% from the prior year.
- EBITDA Margin for Q1 2026 stood at 7057.38%, down from 42.1% in the prior quarter.
- Across five years, EBITDA Margin topped out at 42.1% in Q4 2025 and bottomed at 7057.38% in Q1 2026.
- The 5-year median for EBITDA Margin is 690.26% (2022), against an average of 1191.58%.
- The widest annual swing landed in 2025, when EBITDA Margin soared 147206 bps; it then sank 643261 bps in 2026.
- A 5-year view of EBITDA Margin shows it stood at 358.56% in 2022, then slumped by 179 bps to 999.59% in 2023, then plunged by 31 bps to 1309.33% in 2024, then jumped by 97 bps to 42.1% in 2025, then tumbled by 16664 bps to 7057.38% in 2026.
- The last three EBITDA Margin figures came in at 7057.38% (Q1 2026), 42.1% (Q4 2025), and 504.58% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 1,216,509.61 Bn | 1,216,509.61 Bn | - | - |
| 2 | Alterity Therapeutics | 764,224.41 Bn | 764,224.38 Bn | - | - |
| 3 | Legend Biotech | 2,716.00 Bn | 2,715.71 Bn | 242.10 Mn | -6.43% |
| 4 | Nanobiotix | 2,248.83 Bn | 2,248.77 Bn | - | - |
| 5 | Akari Therapeutics | 1,951.18 Bn | 1,951.17 Bn | - | - |
| 6 | Vertex Pharmaceuticals | 113.69 Bn | 106.44 Bn | 2.59 Bn | 38.10% |
| 7 | Evaxion A | 64.16 Bn | 64.14 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 63.94 Bn | 55.18 Bn | 3.31 Bn | 18.35% |
| 9 | Alnylam Pharmaceuticals | 40.13 Bn | 37.12 Bn | 959.66 Mn | 17.24% |
| 10 | Bicycle Therapeutics | 326.82 Mn | 326.82 Mn | - | -7,057.38% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -7,057.38% |
| Dec 31, 2025 | -42.10% |
| Sep 30, 2025 | -504.58% |
| Jun 30, 2025 | -2,768.97% |
| Mar 31, 2025 | -624.78% |
| Dec 31, 2024 | -1,309.33% |
| Sep 30, 2024 | -1,976.64% |
| Jun 30, 2024 | -428.65% |
| Mar 31, 2024 | -250.36% |
| Dec 31, 2023 | -999.59% |
| Sep 30, 2023 | -862.03% |
| Jun 30, 2023 | -382.13% |
| Mar 31, 2023 | -804.33% |
| Dec 31, 2022 | -358.56% |
| Sep 30, 2022 | -902.80% |
| Jun 30, 2022 | -294.45% |
| Mar 31, 2022 | -690.26% |
| Dec 31, 2021 | -1,139.50% |
| Sep 30, 2021 | -331.53% |
| Jun 30, 2021 | -1,017.82% |
| Mar 31, 2021 | -898.73% |
| Dec 31, 2020 | -458.65% |
| Sep 30, 2020 | -244.53% |
| Jun 30, 2020 | -771.23% |
| Mar 31, 2020 | -1,196.46% |
| Dec 31, 2019 | -63.13% |
| Sep 30, 2019 | -1,613.36% |
| Jun 30, 2019 | -770.63% |
| Mar 31, 2019 | -84.95% |
| Dec 31, 2018 | -668.21% |
| Sep 30, 2018 | -511.12% |
| Jun 30, 2018 | -459.72% |
| Mar 31, 2018 | -104.34% |