Bicycle Therapeutics (BCYC) EBITDA (2018 - 2026)
Bicycle Therapeutics (BCYC) reported EBITDA of -$62.6 million for Q1 2026, little changed on a YoY basis from -$62.9 million in Q1 2025, and down 210.08% quarter-over-quarter from -$20.2 million in Q4 2025.
Bicycle Therapeutics (BCYC) EBITDA (2018 - 2026) Analysis & Trends
Bicycle Therapeutics has reported EBITDA for 9 years, with the latest figure at -$62.6 million in Q1 2026.
- For the quarter ending Q1 2026, EBITDA changed 0.43% year-over-year to -$62.6 million; the trailing twelve-month figure through Mar 2026 stood at -$222.8 million (down 9.29% YoY), and the FY2025 full-year result was -$222.6 million, down 32.8% from the prior year.
- EBITDA for Q1 2026 stood at -$62.6 million, down from -$20.2 million in the prior quarter.
- The five-year high for EBITDA was -$20.2 million in Q4 2025, with the low at -$80.9 million in Q2 2025.
- Historically, EBITDA has averaged -$43.8 million across 5 years, with a median of -$43.6 million in 2023.
- The largest YoY upside for EBITDA was 58.42% in 2025 against a maximum downside of 139.41% in 2025.
- Bicycle Therapeutics' EBITDA stood at -$30.1 million in 2022, then tumbled by 76.92% to -$53.3 million in 2023, then increased by 8.89% to -$48.6 million in 2024, then soared by 58.42% to -$20.2 million in 2025, then tumbled by 210.08% to -$62.6 million in 2026.
- The last three EBITDA figures came in at -$62.6 million (Q1 2026), -$20.2 million (Q4 2025), and -$59.2 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | -26.92 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -13.63 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -14.44 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | -752,618.00 |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -65.83 Mn |
| 10 | Bicycle Therapeutics | 278.04 Mn | 278.04 Mn | - | -62.60 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -62.60 Mn |
| Dec 31, 2025 | -20.19 Mn |
| Sep 30, 2025 | -59.21 Mn |
| Jun 30, 2025 | -80.85 Mn |
| Mar 31, 2025 | -62.33 Mn |
| Dec 31, 2024 | -48.55 Mn |
| Sep 30, 2024 | -52.90 Mn |
| Jun 30, 2024 | -40.13 Mn |
| Mar 31, 2024 | -26.04 Mn |
| Dec 31, 2023 | -53.29 Mn |
| Sep 30, 2023 | -46.14 Mn |
| Jun 30, 2023 | -43.55 Mn |
| Mar 31, 2023 | -39.38 Mn |
| Dec 31, 2022 | -30.12 Mn |
| Sep 30, 2022 | -27.45 Mn |
| Jun 30, 2022 | -24.73 Mn |
| Mar 31, 2022 | -26.64 Mn |
| Dec 31, 2021 | -18.23 Mn |
| Sep 30, 2021 | -14.37 Mn |
| Jun 30, 2021 | -18.17 Mn |