Bicycle Therapeutics (BCYC) EBITDA (2018 - 2026)
Bicycle Therapeutics posted quarterly EBITDA of -$62.6 million for Q1 2026, little changed year-on-year from -$62.9 million in Q1 2025, and down 210.08% on a QoQ basis from -$20.2 million in Q4 2025.
Bicycle Therapeutics (BCYC) has 9 years of EBITDA data on file, last reported at -$62.6 million in Q1 2026.
- For the quarter ending Q1 2026, EBITDA changed 0.43% year-over-year to -$62.6 million; the trailing twelve-month figure through Mar 2026 stood at -$222.8 million (down 9.29% YoY), and the FY2025 full-year result was -$222.6 million, down 32.8% from the prior year.
- EBITDA for Q1 2026 stood at -$62.6 million, down from -$20.2 million in the prior quarter.
- Across five years, EBITDA topped out at -$20.2 million in Q4 2025 and bottomed at -$80.9 million in Q2 2025.
- The 5-year median for EBITDA is -$43.6 million (2023), against an average of -$43.8 million.
- Peak annual rise in EBITDA reached 58.42% in 2025, while the deepest fall reached 139.41% in 2025.
- A 5-year view of EBITDA shows it stood at -$30.1 million in 2022, then slumped by 76.92% to -$53.3 million in 2023, then rose by 8.89% to -$48.6 million in 2024, then jumped by 58.42% to -$20.2 million in 2025, then slumped by 210.08% to -$62.6 million in 2026.
- The last three EBITDA figures came in at -$62.6 million (Q1 2026), -$20.2 million (Q4 2025), and -$59.2 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 1,216,509.61 Bn | 1,216,509.61 Bn | - | -13.63 Mn |
| 2 | Alterity Therapeutics | 764,224.41 Bn | 764,224.38 Bn | - | - |
| 3 | Legend Biotech | 2,716.00 Bn | 2,715.71 Bn | 242.10 Mn | -19.70 Mn |
| 4 | Nanobiotix | 2,248.83 Bn | 2,248.77 Bn | - | - |
| 5 | Akari Therapeutics | 1,951.18 Bn | 1,951.17 Bn | - | -14.44 Mn |
| 6 | Vertex Pharmaceuticals | 113.69 Bn | 106.44 Bn | 2.59 Bn | 1.14 Bn |
| 7 | Evaxion A | 64.16 Bn | 64.14 Bn | - | -3.82 Mn |
| 8 | Regeneron Pharmaceuticals | 63.94 Bn | 55.18 Bn | 3.31 Bn | 661.60 Mn |
| 9 | Alnylam Pharmaceuticals | 40.13 Bn | 37.12 Bn | 959.66 Mn | 201.19 Mn |
| 10 | Bicycle Therapeutics | 326.82 Mn | 326.82 Mn | - | -62.60 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -62.60 Mn |
| Dec 31, 2025 | -20.19 Mn |
| Sep 30, 2025 | -59.21 Mn |
| Jun 30, 2025 | -80.85 Mn |
| Mar 31, 2025 | -62.33 Mn |
| Dec 31, 2024 | -48.55 Mn |
| Sep 30, 2024 | -52.90 Mn |
| Jun 30, 2024 | -40.13 Mn |
| Mar 31, 2024 | -26.04 Mn |
| Dec 31, 2023 | -53.29 Mn |
| Sep 30, 2023 | -46.14 Mn |
| Jun 30, 2023 | -43.55 Mn |
| Mar 31, 2023 | -39.38 Mn |
| Dec 31, 2022 | -30.12 Mn |
| Sep 30, 2022 | -27.45 Mn |
| Jun 30, 2022 | -24.73 Mn |
| Mar 31, 2022 | -26.64 Mn |
| Dec 31, 2021 | -18.23 Mn |
| Sep 30, 2021 | -14.37 Mn |
| Jun 30, 2021 | -18.17 Mn |
| Mar 31, 2021 | -16.25 Mn |
| Dec 31, 2020 | -17.65 Mn |
| Sep 30, 2020 | -9.40 Mn |
| Jun 30, 2020 | -12.12 Mn |
| Mar 31, 2020 | -13.51 Mn |
| Dec 31, 2019 | -3.33 Mn |
| Sep 30, 2019 | -9.91 Mn |
| Jun 30, 2019 | -11.73 Mn |
| Mar 31, 2019 | -5.42 Mn |
| Dec 31, 2018 | -7.06 Mn |
| Sep 30, 2018 | -8.23 Mn |
| Jun 30, 2018 | -7.64 Mn |
| Mar 31, 2018 | -2.93 Mn |