Bicycle Therapeutics (BCYC) EBIT (2018 - 2026)

Bicycle Therapeutics posted quarterly EBIT of -$65.5 million for Q1 2026, up 6.73% year-on-year from -$61.4 million in Q1 2025, and down 165.02% on a QoQ basis from -$24.7 million in Q4 2025.

Bicycle Therapeutics (BCYC) has 9 years of EBIT data on file, last reported at -$65.5 million in Q1 2026.

  • For the quarter ending Q1 2026, EBIT rose 6.73% year-over-year to -$65.5 million; the trailing twelve-month figure through Mar 2026 stood at -$242.3 million (up 2.42% YoY), and the FY2025 full-year result was -$247.1 million, down 17.72% from the prior year.
  • EBIT for Q1 2026 stood at -$65.5 million, down from -$24.7 million in the prior quarter.
  • Across five years, EBIT topped out at -$24.7 million in Q4 2025 and bottomed at -$86.6 million in Q2 2025.
  • The 5-year median for EBIT is -$46.6 million (2024), against an average of -$48.8 million.
  • Peak annual rise in EBIT reached 63.48% in 2025, while the deepest fall reached 121.35% in 2025.
  • A 5-year view of EBIT shows it stood at -$32.2 million in 2022, then slumped by 68.37% to -$54.2 million in 2023, then decreased by 24.76% to -$67.7 million in 2024, then soared by 63.48% to -$24.7 million in 2025, then tumbled by 165.02% to -$65.5 million in 2026.
  • The last three EBIT figures came in at -$65.5 million (Q1 2026), -$24.7 million (Q4 2025), and -$65.6 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -2.97 Mn
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -15.76 Mn
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 64.16 Bn 64.14 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 642.90 Mn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 268.64 Mn
10 Bicycle Therapeutics 326.82 Mn 326.82 Mn - -65.48 Mn

Historic Data

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DateValue
Mar 31, 2026 -65.48 Mn
Dec 31, 2025 -24.71 Mn
Sep 30, 2025 -65.55 Mn
Jun 30, 2025 -86.60 Mn
Mar 31, 2025 -70.20 Mn
Dec 31, 2024 -67.66 Mn
Sep 30, 2024 -63.85 Mn
Jun 30, 2024 -46.65 Mn
Mar 31, 2024 -31.72 Mn
Dec 31, 2023 -54.24 Mn
Sep 30, 2023 -50.80 Mn
Jun 30, 2023 -43.11 Mn
Mar 31, 2023 -41.80 Mn
Dec 31, 2022 -32.21 Mn
Sep 30, 2022 -29.76 Mn
Jun 30, 2022 -27.30 Mn
Mar 31, 2022 -27.38 Mn
Dec 31, 2021 -18.02 Mn
Sep 30, 2021 -14.29 Mn
Jun 30, 2021 -17.28 Mn
Mar 31, 2021 -16.02 Mn
Dec 31, 2020 -17.06 Mn
Sep 30, 2020 -10.68 Mn
Jun 30, 2020 -12.58 Mn
Mar 31, 2020 -11.64 Mn
Dec 31, 2019 -4.76 Mn
Sep 30, 2019 -10.25 Mn
Jun 30, 2019 -7.99 Mn
Mar 31, 2019 -3.29 Mn
Dec 31, 2018 -7.54 Mn
Sep 30, 2018 -6.36 Mn
Jun 30, 2018 -4.96 Mn
Mar 31, 2018 -2.93 Mn